Literature DB >> 23520410

Intermolecular C-O Addition of Carboxylic Acids to Arynes: Synthesis of o-Hydroxyaryl Ketones, Xanthones, 4-Chromanones, and Flavones.

Anton V Dubrovskiy1, Richard C Larock.   

Abstract

An efficient and simple route to biologically and pharmaceutically important o-hydroxyaryl ketones, xanthones, 4-chromanones, and flavones has been developed utilizing readily available carboxylic acids and commercially available o-(trimethylsilyl)aryl triflates.

Entities:  

Year:  2013        PMID： 23520410      PMCID： PMC3600654          DOI： 10.1016/j.tet.2013.01.078

Source DB:  PubMed          Journal:  Tetrahedron        ISSN： 0040-4020            Impact factor:   2.457


  37 in total

1.  Synthesis of xanthones, thioxanthones, and acridones by the coupling of arynes and substituted benzoates.

Authors:  Jian Zhao; Richard C Larock
Journal:  J Org Chem       Date:  2007-01-19       Impact factor: 4.354

2.  Catalytic enantioselective synthesis of flavanones and chromanones.

Authors:  Margaret M Biddle; Michael Lin; Karl A Scheidt
Journal:  J Am Chem Soc       Date:  2007-03-10       Impact factor: 15.419

3.  Discovery of insect anti-juvenile hormones in plants.?2U.

Authors:  W S Bowers; T Ohta; J S Cleere; P A Marsella
Journal:  Science       Date:  1976-08-13       Impact factor: 47.728

4.  Reaction of arynes with amino acid esters.

Authors:  Kentaro Okuma; Nahoko Matsunaga; Noriyoshi Nagahora; Kosei Shioji; Yoshinobu Yokomori
Journal:  Chem Commun (Camb)       Date:  2011-04-12       Impact factor: 6.222

5.  Reversal of chloroquine resistance in Plasmodium falciparum by 9H-xanthene derivatives.

Authors:  Chung-Pu Wu; Donelly A van Schalkwyk; Dale Taylor; Peter J Smith; Kelly Chibale
Journal:  Int J Antimicrob Agents       Date:  2005-08       Impact factor: 5.283

6.  The direct acyl-alkylation of arynes.

Authors:  Uttam K Tambar; Brian M Stoltz
Journal:  J Am Chem Soc       Date:  2005-04-20       Impact factor: 15.419

7.  Microwave-assisted, boron trichloride mediated acylation of phenols-synthesis of (o-hydroxyaryl)(aryl)methanones and xanthones.

Authors:  Lei Zhang; John Y Zhang
Journal:  J Comb Chem       Date:  2006 May-Jun

8.  A 2:1 coupling reaction of arynes with aldehydes via o-quinone methides: straightforward synthesis of 9-arylxanthenes.

Authors:  Hiroto Yoshida; Masahiko Watanabe; Hiroyuki Fukushima; Joji Ohshita; Atsutaka Kunai
Journal:  Org Lett       Date:  2004-10-28       Impact factor: 6.005

9.  Synthesis of pyrido[1,2-a]indole malonates and amines through aryne annulation.

Authors:  Donald C Rogness; Nataliya A Markina; Jesse P Waldo; Richard C Larock
Journal:  J Org Chem       Date:  2012-03-06       Impact factor: 4.354

10.  Rhodium fluorapatite catalyst for the synthesis of trisubstituted olefins via cross coupling of Baylis-Hillman adducts and arylboronic acids.

Authors:  M Lakshmi Kantam; K B Shiva Kumar; B Sreedhar
Journal:  J Org Chem       Date:  2007-12-12       Impact factor: 4.354
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