Literature DB >> 21487614

Reaction of arynes with amino acid esters.

Kentaro Okuma1, Nahoko Matsunaga, Noriyoshi Nagahora, Kosei Shioji, Yoshinobu Yokomori.   

Abstract

An efficient route to a variety of 2-phenylindolin-3-ones from amino acid methyl esters has been developed. The reaction of amino acid methyl esters with benzyne prepared from 2-(trimethylsilyl)phenyl triflate and CsF gave 2-phenylindolin-3-ones in moderate to good yields. © The Royal Society of Chemistry 2011

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Year:  2011        PMID: 21487614     DOI: 10.1039/c1cc11234a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  3 in total

1.  Synthesis of pyrido[1,2-a]indole malonates and amines through aryne annulation.

Authors:  Donald C Rogness; Nataliya A Markina; Jesse P Waldo; Richard C Larock
Journal:  J Org Chem       Date:  2012-03-06       Impact factor: 4.354

2.  A facile approach to 2-alkoxyindolin-3-one and its application to the synthesis of N-benzyl matemone.

Authors:  Makoto Shimizu; Hayao Imazato; Isao Mizota; Yusong Zhu
Journal:  RSC Adv       Date:  2019-06-03       Impact factor: 4.036

3.  Intermolecular C-O Addition of Carboxylic Acids to Arynes: Synthesis of o-Hydroxyaryl Ketones, Xanthones, 4-Chromanones, and Flavones.

Authors:  Anton V Dubrovskiy; Richard C Larock
Journal:  Tetrahedron       Date:  2013-02-04       Impact factor: 2.457

  3 in total

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