Literature DB >> 16677006

Microwave-assisted, boron trichloride mediated acylation of phenols-synthesis of (o-hydroxyaryl)(aryl)methanones and xanthones.

Lei Zhang1, John Y Zhang.   

Abstract

A novel and efficient microwave-assisted, BCl(3) mediated coupling reaction to synthesize o-(hydroxyaryl)(aryl)methanone structures from phenols and acyl chlorides is described. This reaction was further incorporated into a two-step synthesis of biologically interesting xanthones.

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Year:  2006        PMID： 16677006     DOI： 10.1021/cc0501007

Source DB:  PubMed          Journal:  J Comb Chem        ISSN： 1520-4766


  4 in total

Review 1.  Controlled microwave heating in modern organic synthesis: highlights from the 2004-2008 literature.

Authors:  C Oliver Kappe; Doris Dallinger
Journal:  Mol Divers       Date:  2009-04-21       Impact factor: 2.943

2.  Intermolecular C-O Addition of Carboxylic Acids to Arynes: Synthesis of o-Hydroxyaryl Ketones, Xanthones, 4-Chromanones, and Flavones.

Authors:  Anton V Dubrovskiy; Richard C Larock
Journal:  Tetrahedron       Date:  2013-02-04       Impact factor: 2.457

3.  Copper-catalyzed ortho-acylation of phenols with aryl aldehydes and its application in one-step preparation of xanthones.

Authors:  Jun Hu; Enoch A Adogla; Yong Ju; Daping Fan; Qian Wang
Journal:  Chem Commun (Camb)       Date:  2012-10-15       Impact factor: 6.222

4.  Ester dance reaction on the aromatic ring.

Authors:  Kaoru Matsushita; Ryosuke Takise; Kei Muto; Junichiro Yamaguchi
Journal:  Sci Adv       Date:  2020-07-08       Impact factor: 14.136
  4 in total

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