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Literature DB >> 23508175

Translational synthetic chemistry.

Sarathy Kesavan¹, Lisa A Marcaurelle.

Abstract

Mesh：

Substances：

Year: 2013 PMID： 23508175 DOI： 10.1038/nchembio.1207

Source DB: PubMed Journal: Nat Chem Biol ISSN： 1552-4450 Impact factor: 15.040

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22 in total

1. Synthesis of cell-permeable stapled peptide dual inhibitors of the p53-Mdm2/Mdmx interactions via photoinduced cycloaddition.

Authors: Michael M Madden; Avinash Muppidi; Zhenyu Li; Xiaolong Li; Jiandong Chen; Qing Lin
Journal: Bioorg Med Chem Lett Date: 2011-01-07 Impact factor: 2.823

Review 2. Diversity-oriented synthesis: producing chemical tools for dissecting biology.

Authors: Cornelius J O' Connor; Henning S G Beckmann; David R Spring
Journal: Chem Soc Rev Date: 2012-04-10 Impact factor: 54.564

3. A stapled p53 helix overcomes HDMX-mediated suppression of p53.

Authors: Federico Bernal; Mark Wade; Marina Godes; Tina N Davis; David G Whitehead; Andrew L Kung; Geoffrey M Wahl; Loren D Walensky
Journal: Cancer Cell Date: 2010-11-16 Impact factor: 31.743

Review 4. Recent progress in fragment-based lead discovery.

Authors: Michèle N Schulz; Roderick E Hubbard
Journal: Curr Opin Pharmacol Date: 2009-05-27 Impact factor: 5.547

5. Quantifying structure and performance diversity for sets of small molecules comprising small-molecule screening collections.

Authors: Paul A Clemons; J Anthony Wilson; Vlado Dančík; Sandrine Muller; Hyman A Carrinski; Bridget K Wagner; Angela N Koehler; Stuart L Schreiber
Journal: Proc Natl Acad Sci U S A Date: 2011-04-11 Impact factor: 11.205

6. Drug discovery: A question of library design.

Authors: Philip J Hajduk; Warren R J D Galloway; David R Spring
Journal: Nature Date: 2011-02-03 Impact factor: 49.962

7. An analog of the natural steroidal alkaloid cortistatin A potently suppresses Tat-dependent HIV transcription.

Authors: Guillaume Mousseau; Mark A Clementz; Wendy N Bakeman; Nisha Nagarsheth; Michael Cameron; Jun Shi; Phil Baran; Rémi Fromentin; Nicolas Chomont; Susana T Valente
Journal: Cell Host Microbe Date: 2012-07-19 Impact factor: 21.023

8. Route to three-dimensional fragments using diversity-oriented synthesis.

Authors: Alvin W Hung; Alex Ramek; Yikai Wang; Taner Kaya; J Anthony Wilson; Paul A Clemons; Damian W Young
Journal: Proc Natl Acad Sci U S A Date: 2011-04-11 Impact factor: 11.205

9. Fragment-based discovery of bromodomain inhibitors part 2: optimization of phenylisoxazole sulfonamides.

Authors: Paul Bamborough; Hawa Diallo; Jonathan D Goodacre; Laurie Gordon; Antonia Lewis; Jonathan T Seal; David M Wilson; Michael D Woodrow; Chun-Wa Chung
Journal: J Med Chem Date: 2012-01-11 Impact factor: 7.446

10. An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.

Authors: Lisa A Marcaurelle; Eamon Comer; Sivaraman Dandapani; Jeremy R Duvall; Baudouin Gerard; Sarathy Kesavan; Maurice D Lee; Haibo Liu; Jason T Lowe; Jean-Charles Marie; Carol A Mulrooney; Bhaumik A Pandya; Ann Rowley; Troy D Ryba; Byung-Chul Suh; Jingqiang Wei; Damian W Young; Lakshmi B Akella; Nathan T Ross; Yan-Ling Zhang; Daniel M Fass; Surya A Reis; Wen-Ning Zhao; Stephen J Haggarty; Michelle Palmer; Michael A Foley
Journal: J Am Chem Soc Date: 2010-11-10 Impact factor: 15.419

3 in total