OBJECTIVE: The objective of this study was to determine the effect of Sinogram-Affirmed Iterative Reconstruction (SAFIRE) on radiological detection, diagnostic confidence, and image quality at half-dose, contrast-enhanced abdominopelvic computed tomography. METHODS: Forty dual-source examinations were reconstructed using routine-dose with filtered back projection, half-dose filtered back projection, and half-dose SAFIRE. Three radiologists detected lesions in abdominopelvic organs, reporting findings of potential medical significance, diagnostic confidence, and image quality. RESULTS: There was greater than 78% concordance between full- and half-dose images ± SAFIRE, and no difference in the detection of lesions within organs between half-dose images ± SAFIRE (P = 0.22 - 1.0). Detection of potentially important findings varied by reader, but not between dose/reconstruction methods. Diagnostic confidence varied widely (P < 0.001 to P > 0.91). Sinogram-Affirmed Iterative Reconstruction significantly improved image quality in the pelvis (P ≤ 0.04). CONCLUSIONS: Half-dose images ± SAFIRE had organ-specific detections similar to routine-dose images. Sinogram-Affirmed Iterative Reconstruction improved image quality in the pelvis, but diagnostic confidence and image quality scores in the abdomen depended on the reader.
OBJECTIVE: The objective of this study was to determine the effect of Sinogram-Affirmed Iterative Reconstruction (SAFIRE) on radiological detection, diagnostic confidence, and image quality at half-dose, contrast-enhanced abdominopelvic computed tomography. METHODS: Forty dual-source examinations were reconstructed using routine-dose with filtered back projection, half-dose filtered back projection, and half-dose SAFIRE. Three radiologists detected lesions in abdominopelvic organs, reporting findings of potential medical significance, diagnostic confidence, and image quality. RESULTS: There was greater than 78% concordance between full- and half-dose images ± SAFIRE, and no difference in the detection of lesions within organs between half-dose images ± SAFIRE (P = 0.22 - 1.0). Detection of potentially important findings varied by reader, but not between dose/reconstruction methods. Diagnostic confidence varied widely (P < 0.001 to P > 0.91). Sinogram-Affirmed Iterative Reconstruction significantly improved image quality in the pelvis (P ≤ 0.04). CONCLUSIONS: Half-dose images ± SAFIRE had organ-specific detections similar to routine-dose images. Sinogram-Affirmed Iterative Reconstruction improved image quality in the pelvis, but diagnostic confidence and image quality scores in the abdomen depended on the reader.
Authors: Christopher P Favazza; Andrea Ferrero; Lifeng Yu; Shuai Leng; Kyle L McMillan; Cynthia H McCollough Journal: J Med Imaging (Bellingham) Date: 2017-10-03
Authors: Joel G Fletcher; Lifeng Yu; Zhoubo Li; Armando Manduca; Daniel J Blezek; David M Hough; Sudhakar K Venkatesh; Gregory C Brickner; Joseph C Cernigliaro; Amy K Hara; Jeff L Fidler; David S Lake; Maria Shiung; David Lewis; Shuai Leng; Kurt E Augustine; Rickey E Carter; David R Holmes; Cynthia H McCollough Journal: Radiology Date: 2015-05-26 Impact factor: 11.105
Authors: Joel G Fletcher; David L Levin; Anne-Marie G Sykes; Rebecca M Lindell; Darin B White; Ronald S Kuzo; Vighnesh Suresh; Lifeng Yu; Shuai Leng; David R Holmes; Akitoshi Inoue; Matthew P Johnson; Rickey E Carter; Cynthia H McCollough Journal: Radiology Date: 2020-09-29 Impact factor: 11.105