| Literature DB >> 23479275 |
H Nieß1, A Kleespies, J Andrassy, S Pratschke, P Pratschke, M K Angele, M Guba, K-W Jauch, C J Bruns.
Abstract
The considerable increase of the aged population in western civilisation within the next years will result in a rising incidence of pancreatic cancer. Until the year 2020 an increment of 20 % of patients beyond 65 years old can be anticipated. Therefore, the focus will be on management of old and geriatric surgical patients leading to strategical re-evaluation of surgical indications under critical consideration of feasibility and purpose. Even under modern interdisciplinary therapy concepts the prognosis of ductal adenocarcinoma of the pancreas remains poor with an overall 5-year survival rate of less than 5 %. The surgical resection is still considered as the only potential curative treatment option with extended life expectancy; however, it is technically demanding and furthermore associated with significant morbidity. In particular, the quality of surgery of the now interdisciplinary therapy of pancreatic cancer is markedly improved when performed at a high-volume centres. Until now only a few retrospective data analyses evaluating the perioperative and long-term outcome after pancreatic tumor resections in geriatric patients exist. The available results, however, support radical surgical procedures even beyond the age of 75 years.Entities:
Mesh:
Year: 2013 PMID: 23479275 DOI: 10.1007/s00104-012-2455-y
Source DB: PubMed Journal: Chirurg ISSN: 0009-4722 Impact factor: 0.955