Literature DB >> 25234504

[Pancreatic resection in the elderly : Is the risk justified?].

K Feilhauer1, R Hennig, S Lenz, J Köninger.   

Abstract

BACKGROUND: Due to demographic changes and improved diagnostic and therapeutic options surgery in the elderly is an essential field of discussion in medicine. Working groups are becoming increasingly more concerned with the question whether old age is a risk factor for complex surgical procedures.
OBJECTIVE: This study was carried out to help assess and evaluate the risk of pancreatic resection in the elderly.
MATERIAL AND METHODS: In a retrospective analysis of a prospectively maintained database of pancreatic resections, data from a 4-year period were evaluated and analyzed. A division into two age groups was defined according to the literature with the age of 75 years being the dividing line.
RESULTS: During the 4 years of the study 209 pancreatic resections were performed in 146 patients under the age of 75 years and 63 patients over the age of 75 years. A pancreatic head resection was performed in 133 patients, distal pancreatectomy in 57, pancreatectomy in 16 and segmental resection in 3 patients. The overall mortality rate was 2.4 %, only patients over the age of 75 years were affected and was not directly related to surgery in any of the cases. The risk of patients dying perioperatively was significantly increased over the age of 75 years as was the comorbidity rate. Regarding surgically related complications there were no differences between the two groups.
CONCLUSION: Pancreatic resection in elderly patients > 75 years is justified because of the very low surgical morbidity and mortality which can now be achieved in experienced centers if comorbidities of patients are taken into account in the decision-making process. The age per se does not constitute a contraindication.

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Mesh:

Year:  2015        PMID: 25234504     DOI: 10.1007/s00104-014-2869-9

Source DB:  PubMed          Journal:  Chirurg        ISSN: 0009-4722            Impact factor:   0.955


  14 in total

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Authors:  Prashant Sukharamwala; Sukharamwala Prashant; Jonathan Thoens; Thoens Jonathan; Mauricio Szuchmacher; Szuchmacher Mauricio; James Smith; Smith James; Peter DeVito; DeVito Peter
Journal:  HPB (Oxford)       Date:  2012-06-27       Impact factor: 3.647

2.  Risk factors for surgical complications in distal pancreatectomy.

Authors:  Hendrik Seeliger; Simone Christians; Martin K Angele; Axel Kleespies; Martin E Eichhorn; Ivan Ischenko; Stefan Boeck; Volker Heinemann; Karl-Walter Jauch; Christiane J Bruns
Journal:  Am J Surg       Date:  2010-04-09       Impact factor: 2.565

3.  Outcome after pancreaticoduodenectomy for cancer in elderly patients.

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Journal:  J Gastrointest Surg       Date:  2006-06       Impact factor: 3.452

4.  Is pancreaticoduodenectomy justified in elderly patients?

Authors:  A W C Kow; N A Sadayan; A Ernest; B Wang; C Y Chan; C K Ho; K H Liau
Journal:  Surgeon       Date:  2011-03-25       Impact factor: 2.392

5.  Pancreatoduodenectomy for ductal adenocarcinoma in the very elderly; is it safe and justified?

Authors:  Saboor Khan; Guido Sclabas; Kaye Reid Lombardo; Michael G Sarr; David Nagorney; Michael L Kendrick; John H Donohue; Florencia G Que; Michael B Farnell
Journal:  J Gastrointest Surg       Date:  2010-08-17       Impact factor: 3.452

6.  The safety of a pancreaticoduodenectomy in patients older than 80 years: risk vs. benefits.

Authors:  Marcovalerio Melis; Francesca Marcon; Antonio Masi; Antonio Pinna; Umut Sarpel; George Miller; Harvey Moore; Steven Cohen; Russell Berman; H Leon Pachter; Elliot Newman
Journal:  HPB (Oxford)       Date:  2012-05-29       Impact factor: 3.647

7.  Results of pancreatic surgery in the elderly: is age a barrier?

Authors:  Melissa Oliveira-Cunha; Deep J Malde; Amer Aldouri; Gareth Morris-Stiff; Krishna V Menon; Andrew Malvern Smith
Journal:  HPB (Oxford)       Date:  2012-08-26       Impact factor: 3.647

Review 8.  What is the effect of age on pancreatic resection?

Authors:  Taylor S Riall
Journal:  Adv Surg       Date:  2009

9.  Surgical treatment of pancreatic head carcinoma in elderly patients.

Authors:  Stefania Brozzetti; Gianluca Mazzoni; Michelangelo Miccini; Francesco Puma; Monica De Angelis; Diletta Cassini; Elia Bettelli; Adriano Tocchi; Antonino Cavallaro
Journal:  Arch Surg       Date:  2006-02

10.  Pancreaticoduodenectomy of pancreatic ductal adenocarcinoma in the elderly.

Authors:  Chang Moo Kang; Jun Young Kim; Gi Hong Choi; Kyung Sik Kim; Jin Sub Choi; Woo Jung Lee; Byong Ro Kim
Journal:  Yonsei Med J       Date:  2007-06-30       Impact factor: 2.759

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Authors:  Thorben W Fründt; Christian Casar; Johann von Felden; Ulrike Schöler; Maximilian Priebe; Jenny Kraczyk; Hannes Ahrend; Johannes Salamon; Gerhard Adam; Samuel Huber; Ansgar W Lohse; Henning Wege; Kornelius Schulze
Journal:  Cancers (Basel)       Date:  2022-02-01       Impact factor: 6.639

2.  Short- and Long-Term Outcomes of Pancreatic Cancer Resection in Elderly Patients: A Nationwide Analysis.

Authors:  I Quintus Molenaar; Hjalmar C van Santvoort; Anne Claire Henry; Thijs J Schouten; Lois A Daamen; Marieke S Walma; Peter Noordzij; Geert A Cirkel; Maartje Los; Marc G Besselink; Olivier R Busch; Bert A Bonsing; Koop Bosscha; Ronald M van Dam; Sebastiaan Festen; Bas Groot Koerkamp; Erwin van der Harst; Ignace H J T de Hingh; Geert Kazemier; Mike S Liem; Vincent E de Meijer; Vincent B Nieuwenhuijs; Daphne Roos; Jennifer M J Schreinemakers; Martijn W J Stommel
Journal:  Ann Surg Oncol       Date:  2022-06-02       Impact factor: 4.339

  2 in total

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