Literature DB >> 23477423

Release of metal ions from fixed orthodontic appliance: an in vitro study in continuous flow system.

Marcin Mikulewicz1, Katarzyna Chojnacka, Paulina Wołowiec.   

Abstract

OBJECTIVE: To evaluate the release of metal ions from fixed orthodontic appliances.
MATERIALS AND METHODS: A new system for in vitro testing of dental materials was constructed and consisted of a thermostatic glass reactor that enabled immersion of the studied material. Experimental conditions reflected the human oral cavity, with a temperature of 37°C and a saliva flow rate of 0.5mL/min. The simulated fixed orthodontic appliance made of stainless steel was evaluated. Sampling was performed at several time points during the 28-day study, and the metal ion concentration was determined by inductively coupled plasma optical emission spectrometry.
RESULTS: The total mass of released metal ions from the appliance during 4 weeks of the experiment was as follows nickel 18.7 μg, chromium 5.47 μg, copper 31.3 μg.
CONCLUSIONS: The estimated doses of nickel, chromium, and copper determined by extrapolation of experimental data released during the treatment period were far below the toxic dose to humans. This shows that orthodontic treatment might not be a significant source of exposure to these metal ions.

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Year:  2013        PMID: 23477423      PMCID: PMC8683050          DOI: 10.2319/113012-911.1

Source DB:  PubMed          Journal:  Angle Orthod        ISSN: 0003-3219            Impact factor:   2.079


  23 in total

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Authors:  Robert P Kusy
Journal:  Angle Orthod       Date:  2002-12       Impact factor: 2.079

2.  The unstimulated salivary flow rate after prolonged gum chewing.

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Journal:  Arch Oral Biol       Date:  2004-12-10       Impact factor: 2.633

Review 3.  Intraoral aging of orthodontic materials: the picture we miss and its clinical relevance.

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Journal:  Am J Orthod Dentofacial Orthop       Date:  2005-04       Impact factor: 2.650

4.  Change in nickel levels in the saliva of patients with fixed orthodontic appliances.

Authors:  Lahcen Ousehal; Laila Lazrak
Journal:  Int Orthod       Date:  2012-04-24

5.  Evaluation of the genotoxic effects of fixed appliances on oral mucosal cells and the relationship to nickel and chromium concentrations: an in-vivo study.

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Journal:  Am J Orthod Dentofacial Orthop       Date:  2011-09       Impact factor: 2.650

6.  Salivary nickel and chromium in patients with fixed orthodontic appliances.

Authors:  L Kocadereli; P A Ataç; P S Kale; D Ozer
Journal:  Angle Orthod       Date:  2000-12       Impact factor: 2.079

7.  Nickel and chromium levels in the saliva and serum of patients with fixed orthodontic appliances.

Authors:  G Ağaoğlu; T Arun; B Izgi; A Yarat; B Izgü
Journal:  Angle Orthod       Date:  2001-10       Impact factor: 2.079

8.  Metal release from simulated fixed orthodontic appliances.

Authors:  C J Hwang; J S Shin; J Y Cha
Journal:  Am J Orthod Dentofacial Orthop       Date:  2001-10       Impact factor: 2.650

9.  In vivo study of metal content of oral mucosa cells in patients with and without fixed orthodontic appliances.

Authors:  F Amini; A Borzabadi Farahani; A Jafari; M Rabbani
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10.  Release of nickel ions from stainless steel alloys used in dental braces and their patch test reactivity in nickel-sensitive individuals.

Authors:  Christian Stab Jensen; Steen Lisby; Ole Baadsgaard; Kirsten Byrialsen; Torkil Menné
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4.  Mapping chemical elements on the surface of orthodontic appliance by SEM-EDX.

Authors:  Marcin Mikulewicz; Paulina Wołowiec; Izabela Michalak; Katarzyna Chojnacka; Wojciech Czopor; Adam Berniczei-Royko; Andras Vegh; Thomas Gedrange
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6.  Trace Elements in Living Systems: From Beneficial to Toxic Effects.

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7.  Metals and Metalloids Release from Orthodontic Elastomeric and Stainless Steel Ligatures: In Vitro Risk Assessment of Human Exposure.

Authors:  Aneta Olszewska; Anetta Hanć; Danuta Barałkiewicz; Piotr Rzymski
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8.  Comparative Toxicological In Vitro and In Ovo Screening of Different Orthodontic Implants Currently Used in Dentistry.

Authors:  Camelia A Szuhanek; Claudia G Watz; Ștefana Avram; Elena-Alina Moacă; Ciprian V Mihali; Adelina Popa; Andrada A Campan; Mirela Nicolov; Cristina A Dehelean
Journal:  Materials (Basel)       Date:  2020-12-13       Impact factor: 3.623

9.  Are Metal Ions That Make up Orthodontic Alloys Cytotoxic, and Do They Induce Oxidative Stress in a Yeast Cell Model?

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10.  Metallurgical and electrochemical characterization of contemporary silver-based soldering alloys.

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  10 in total

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