Literature DB >> 23471191

THE ROLE OF POROUS MEDIA IN MODELING FLUID FLOW WITHIN HOLLOW FIBER MEMBRANES OF THE TOTAL ARTIFICIAL LUNG.

Khalil Khanafer1, Keith Cook, Alia Marafie.   

Abstract

A numerical study was conducted to analyze fluid flow within hollow fiber membranes of the artificial lungs. The hollow fiber bundle was approximated using a porous media model. In addition, the transport equations were solved using the finite-element formulation based on the Galerkin method of weighted residuals. Comparisons with previously published work on the basis of special cases were performed and found to be in excellent agreement. A Newtonian viscous fluid model for the blood was used. Different flow models for porous media, such as the Brinkman-extended Darcy model, Darcy's law model, and the generalized flow model, were considered. Results were obtained in terms of streamlines, velocity vectors, and pressure distribution for various Reynolds numbers and Darcy numbers. The results from this investigation showed that the pressure drop across the artificial lung device increased with an increase in the Reynolds number. In addition, the pressure drop was found to increase significantly for small Darcy numbers.

Entities:  

Keywords:  artificial lung; blood oxygenation; hollow fiber membrane

Year:  2010        PMID: 23471191      PMCID: PMC3587718          DOI: 10.1615/JPorMedia.v15.i2.20

Source DB:  PubMed          Journal:  J Porous Media        ISSN: 1091-028X            Impact factor:   1.663


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