| Literature DB >> 234627 |
R J Wyatt, E Erdelyi, J R DoAmaral, G R Elliott, J Renson, J D Barchas.
Abstract
An enzymatic preparation from human brain converts tryptamine to tryptoline (9H-1,2,3,4-tetrahydropyrido[3,4-b]indole) in the presence of 5-methyltetrahydrofolic acid. Similarly, N-methyltryptamine and 5-hydroxytryptamine yield 1-methyltryptoline and 5-hydroxytryptoline, respectively. Neither in vitro nor in vivo formation of these compounds by human tissues has been described.Entities:
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Year: 1975 PMID： 234627 DOI： 10.1126/science.234627
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728