Literature DB >> 23456639

A simple route for the synthesis of novel N-alkyl-2-(alkylthio)-1H-imidazole derivatives.

Ebrahim Kianmehr1, Narges Shamsaei Zafarghandi, Mohammad Ghanbari.   

Abstract

Novel N-alkyl-2-(alkylthio)-1H-imidazole derivatives were synthesized in a single step by an efficient and simple method in high yields. Readily available starting materials, mild reaction conditions, operational simplicity and novelty are the key advantages of this method. Besides their novel structures, these compounds may have important biological activities and industrial applications.

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Year:  2013        PMID: 23456639     DOI: 10.1007/s11030-013-9430-5

Source DB:  PubMed          Journal:  Mol Divers        ISSN: 1381-1991            Impact factor:   2.943


  12 in total

Review 1.  Imidazole, oxazole and thiazole alkaloids.

Authors:  Zhong Jin
Journal:  Nat Prod Rep       Date:  2006-03-28       Impact factor: 13.423

2.  Novel one-pot three component reaction for the synthesis of [2-(alkylsulfanyl)imidazo[1,2-a]pyridin-3-yl](aryl)methanone.

Authors:  Ebrahim Kianmehr; Mohammad Ghanbari; Mehri Nadiri Niri; Reza Faramarzi
Journal:  J Comb Chem       Date:  2010 Jan-Feb

3.  Novel annulation reactions of aryl methyl ketenes with zwitterions derived from dimethyl acetylenedicarboxylate and N-alkylimidazoles.

Authors:  Cheng Ma; Hanfeng Ding; Yanguang Wang
Journal:  Org Lett       Date:  2006-07-06       Impact factor: 6.005

4.  Benzimidazoles as non-peptide luteinizing hormone-releasing hormone (LHRH) antagonists. Part 3: Discovery of 1-(1H-benzimidazol-5-yl)-3-tert-butylurea derivatives.

Authors:  Miyuki Tatsuta; Mikayo Kataoka; Kayo Yasoshima; Sachiko Sakakibara; Yuka Shogase; Makoto Shimazaki; Takeshi Yura; Yingfu Li; Noriyuki Yamamoto; Jang Gupta; Klaus Urbahns
Journal:  Bioorg Med Chem Lett       Date:  2005-05-02       Impact factor: 2.823

Review 5.  Omeprazole. An updated review of its pharmacology and therapeutic use in acid-related disorders.

Authors:  D McTavish; M M Buckley; R C Heel
Journal:  Drugs       Date:  1991-07       Impact factor: 9.546

Review 6.  Imidazole and benzimidazole derivatives as chemotherapeutic agents.

Authors:  Mariana Boiani; Mercedes González
Journal:  Mini Rev Med Chem       Date:  2005-04       Impact factor: 3.862

Review 7.  Lansoprazole. A review of its pharmacodynamic and pharmacokinetic properties and its therapeutic efficacy in acid-related disorders.

Authors:  L B Barradell; D Faulds; D McTavish
Journal:  Drugs       Date:  1992-08       Impact factor: 9.546

8.  One-pot microwave-assisted protocol for the synthesis of substituted 2-amino-1H-imidazoles.

Authors:  D S Ermolat'ev; B Savaliya; A Shah; E Van der Eycken
Journal:  Mol Divers       Date:  2010-08-26       Impact factor: 2.943

9.  Wells-Dawson heteropolyacid supported on silica: a highly efficient catalyst for synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles.

Authors:  Ali Reza Karimi; Zahra Alimohammadi; Mostafa M Amini
Journal:  Mol Divers       Date:  2009-10-29       Impact factor: 2.943

10.  Structure-activity relationships among 2-substituted 5,6-dichloro-, 4,6-dichloro-, and 4,5-dichloro-1-[(2-hydroxyethoxy) methyl]- and -1-[(1,3-dihydroxy-2-propoxy) methyl]benzimidazoles.

Authors:  S Saluja; R Zou; J C Drach; L B Townsend
Journal:  J Med Chem       Date:  1996-02-16       Impact factor: 7.446

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