Literature DB >> 23440931

Improving adverse drug event detection in critically ill patients through screening intensive care unit transfer summaries.

Ananth M Anthes1, Lisa M Harinstein, Pamela L Smithburger, Amy L Seybert, Sandra L Kane-Gill.   

Abstract

PURPOSE: This study aimed to determine the frequency and type of adverse drug events (ADEs) identified in intensive care unit (ICU) transfer summaries and in the hospital discharge summaries to demonstrate the effectiveness of ICU transfer summary surveillance in the identification of ADEs.
METHODS: A retrospective electronic medical record review was conducted for medical ICU patients admitted between January 2009 and April 2009 to a large, academic medical center. The Harvard Practice Scale and the modified Leonard Assessment Scale were used to evaluate the presence of an ADE from the ICU transfer and hospital discharge summaries.
RESULTS: Two hundred and fifty-four patients were identified for inclusion with a median medical ICU length of stay of 4.5 days and hospital length of stay of 13 days. The ICU transfer summary review revealed 173 ADEs among 124 unique patients with a rate of 33.9 ADEs per 1000 hospital patient days. Sixty-nine ADEs among 63 unique patients were identified through the hospital discharge summary with a rate of 13.5 ADEs per 1000 hospital patient days. Only 23.1% of ADEs discussed in the ICU transfer summary were also discussed in the hospital discharge summary.
CONCLUSIONS: The use of ICU transfer summaries is an effective tool to increase ADE detection. The use of an ICU transfer summary should be considered as an adjunct method to an existing ADE surveillance system for heightened pharmacovigilance.
Copyright © 2013 John Wiley & Sons, Ltd.

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Year:  2013        PMID: 23440931     DOI: 10.1002/pds.3422

Source DB:  PubMed          Journal:  Pharmacoepidemiol Drug Saf        ISSN: 1053-8569            Impact factor:   2.890


  8 in total

1.  Dense Annotation of Free-Text Critical Care Discharge Summaries from an Indian Hospital and Associated Performance of a Clinical NLP Annotator.

Authors:  S V Ramanan; Kedar Radhakrishna; Abijeet Waghmare; Tony Raj; Senthil P Nathan; Sai Madhukar Sreerama; Sriram Sampath
Journal:  J Med Syst       Date:  2016-06-24       Impact factor: 4.460

2.  Use of Text Searching for Trigger Words in Medical Records to Identify Adverse Drug Reactions within an Intensive Care Unit Discharge Summary.

Authors:  Sandra L Kane-Gill; Adam M MacLasco; Melissa I Saul; Tiffany R Politz Smith; Megan A Kloet; Catherine Kim; Ananth M Anthes; Pamela L Smithburger; Amy L Seybert
Journal:  Appl Clin Inform       Date:  2016-07-13       Impact factor: 2.342

3.  A Multicenter Evaluation of Off-Label Medication Use and Associated Adverse Drug Reactions in Adult Medical ICUs.

Authors:  Pamela L Smithburger; Mitchell S Buckley; Mark A Culver; Sarah Sokol; Ishaq Lat; Steven M Handler; Levent Kirisci; Sandra L Kane-Gill
Journal:  Crit Care Med       Date:  2015-08       Impact factor: 7.598

4.  Determining the incidence of drug-associated acute kidney injury in nursing home residents.

Authors:  Steven M Handler; Pui Wen Cheung; Colleen M Culley; Subashan Perera; Sandra L Kane-Gill; John A Kellum; Zachary A Marcum
Journal:  J Am Med Dir Assoc       Date:  2014-05-10       Impact factor: 4.669

5.  Implementation of pharmacists' interventions and assessment of medication errors in an intensive care unit of a Chinese tertiary hospital.

Authors:  Sai-Ping Jiang; Jian Chen; Xing-Guo Zhang; Xiao-Yang Lu; Qing-Wei Zhao
Journal:  Ther Clin Risk Manag       Date:  2014-10-09       Impact factor: 2.423

Review 6.  Clinical decision support for drug related events: Moving towards better prevention.

Authors:  Sandra L Kane-Gill; Archita Achanta; John A Kellum; Steven M Handler
Journal:  World J Crit Care Med       Date:  2016-11-04

7.  Impact of targeted educational interventions on appropriateness of stress ulcer prophylaxis in critically ill adults.

Authors:  Drayton A Hammond; Catherine A Killingsworth; Jacob T Painter; Rose E Pennick; Kshitij Chatterjee; Bradley Boye; Nikhil Meena
Journal:  Pharm Pract (Granada)       Date:  2017-08-15

8.  Trigger tools are as effective as non-targeted chart review for adverse drug event detection in intensive care units.

Authors:  Renato R Martins; Lunara T Silva; Gabriela G Bessa; Flavio M Lopes
Journal:  Saudi Pharm J       Date:  2018-07-20       Impact factor: 4.330

  8 in total

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