Literature DB >> 23410017

Oral cancer in India continues in epidemic proportions: evidence base and policy initiatives.

Bhawna Gupta1, Anura Ariyawardana, Newell W Johnson.   

Abstract

OBJECTIVES: India has the highest number of cases of oral cancer in the world and this is increasing. This burden is not fully appreciated even within India, despite the high incidence and poor survival associated with this disease. Because the aetiology of oral cancer is predominantly tobacco-related, the immense public health challenge can be ameliorated through habit intervention.
METHODS: We reviewed current rates of incidence, mortality and survival, and investigated the determinants of disease and current prevention strategies.
RESULTS: In addition to tobacco smoking and the myriad other forms of tobacco use prevalent in India, risk factors include areca nut consumption, alcohol consumption, human papillomavirus, increasing age, male gender and socioeconomic factors. Although India has world-leading cancer treatment centres, access to these is limited. Further, the focus of health care services remains clinical and is either curative or palliative.
CONCLUSIONS: Although the efforts of agencies such as the Ministry of Health and Family Welfare and the Indian Dental Association are laudable, enhanced strategies should be based on common risk factors, focusing on primary prevention, health education, early detection and the earliest possible therapeutic intervention. A multi-agency approach is required.
© 2012 FDI World Dental Federation.

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Mesh:

Year:  2012        PMID: 23410017      PMCID: PMC9374955          DOI: 10.1111/j.1875-595x.2012.00131.x

Source DB:  PubMed          Journal:  Int Dent J        ISSN: 0020-6539            Impact factor:   2.607


  53 in total

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3.  Bidi smoking and health.

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4.  Tobacco control policies in India: implementation and challenges.

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Review 5.  Epidemiology of betel quid usage.

Authors:  P C Gupta; C S Ray
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Review 6.  Chemoprevention of oral squamous cell carcinomas.

Authors:  M Scheer; A C Kuebler; J E Zöller
Journal:  Onkologie       Date:  2004-04

7.  Quality of life in oral carcinoma: a 5-year prospective study.

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8.  Cost-effectiveness of oral cancer screening: results from a cluster randomized controlled trial in India.

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9.  Human papillomavirus and risk of oral cancer.

Authors:  E M Smith; H T Hoffman; K S Summersgill; H L Kirchner; L P Turek; T H Haugen
Journal:  Laryngoscope       Date:  1998-07       Impact factor: 3.325

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Authors:  Susan Furness; Anne-Marie Glenny; Helen V Worthington; Sue Pavitt; Richard Oliver; Jan E Clarkson; Michaelina Macluskey; Kelvin Kw Chan; David I Conway
Journal:  Cochrane Database Syst Rev       Date:  2011-04-13
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  36 in total

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Review 2.  Cancer of the gingiva.

Authors:  Rusana Bark; Claes Mercke; Eva Munck-Wikland; Natalie Ann Wisniewski; Lalle Hammarstedt-Nordenvall
Journal:  Eur Arch Otorhinolaryngol       Date:  2015-02-04       Impact factor: 2.503

3.  Parthenolide attenuates 7,12-dimethylbenz[a]anthracene induced hamster buccal pouch carcinogenesis.

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Journal:  Mol Cell Biochem       Date:  2017-08-12       Impact factor: 3.396

4.  Genome-wide mitochondrial DNA sequence variations and lower expression of OXPHOS genes predict mitochondrial dysfunction in oral cancer tissue.

Authors:  Esita Chattopadhyay; Navonil De Sarkar; Richa Singh; Anindita Ray; Roshni Roy; Ranjan Rashmi Paul; Mousumi Pal; Sandip Ghose; Subhrendu Ghosh; Debajyoti Kabiraj; Raja Banerjee; Bidyut Roy
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5.  Human ex-vivo oral tissue imaging using spectral domain polarization sensitive optical coherence tomography.

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Journal:  Lasers Med Sci       Date:  2016-11-02       Impact factor: 3.161

6.  Oral cancer incidence and mortality in China, 2011.

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Journal:  Chin J Cancer Res       Date:  2015-02       Impact factor: 5.087

7.  Integrated genomic analyses identify KDM1A's role in cell proliferation via modulating E2F signaling activity and associate with poor clinical outcome in oral cancer.

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Review 8.  Assessment of the Status of National Oral Health Policy in India.

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Review 9.  Life course models for upper aero-digestive tract cancer.

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Journal:  Int Dent J       Date:  2015-05-01       Impact factor: 2.607

10.  Effects of interleukin-18 promoter (C607A and G137C) gene polymorphisms and their association with oral squamous cell carcinoma (OSCC) in northern India.

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