| Literature DB >> 27807650 |
Priyanka Sharma1,2, Yogesh Verma3,4, Khageswar Sahu3, Sudhir Kumar3, Amit V Varma5, Jyoti Kumawat3, Pradeep Kumar Gupta6.
Abstract
We report the use of spectral domain polarization sensitive optical coherence tomography for ex-vivo imaging of human oral mandibular tissue samples. Our results show that compared to the changes observed in the epithelium thickness and the decay constant of A-scan intensity profile, a much larger degree of change was observed in the phase retardation for tissue sites progressing from normal to the malignant state. These results suggest that monitoring of tissue retardance can help in better differentiation of normal and cancerous oral tissue sites.Entities:
Keywords: Collagen; Optical coherence tomography; Oral cancer; Spectral domain polarization sensitive optical coherence tomography; Submucosal fibrosis; Trichrome staining
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Year: 2016 PMID: 27807650 DOI: 10.1007/s10103-016-2096-3
Source DB: PubMed Journal: Lasers Med Sci ISSN: 0268-8921 Impact factor: 3.161