Takumi Hori1, Nobuo Sanjo, Makoto Tomita, Hidehiro Mizusawa. 1. Department of Neurology and Neurological Science, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Tokyo, Japan.
Abstract
BACKGROUND: The Visual Reproduction (VR) test is used to assess mild cognitive impairment (MCI), but the characteristics of visual memory in Japanese MCI patients remain unclear. METHODS: VR scores of 27 MCI patients were evaluated using the Wechsler Memory Scale-Revised. Scores of MCI, no-dementia, and Alzheimer's disease (AD) groups were then compared. RESULTS: The annual conversion rate of MCI to AD was 18.8%. Mean VR-I and VR-II baseline scores for MCI patients were 33.3 ± 5.6 and 20.5 ± 14.0, respectively. Mean VR-II scores for converted and nonconverted MCI patients were 7.2 ± 8.7 and 29.8 ± 9.3, respectively. CONCLUSIONS: It is likely that VR-II and VR-II/I scores are more sensitive for predicting conversion to AD in Japanese than in American MCI patients. Our results indicate that VR is a sensitive and useful measure for predicting the conversion of Japanese MCI patients to AD within 2 years.
BACKGROUND: The Visual Reproduction (VR) test is used to assess mild cognitive impairment (MCI), but the characteristics of visual memory in Japanese MCI patients remain unclear. METHODS: VR scores of 27 MCI patients were evaluated using the Wechsler Memory Scale-Revised. Scores of MCI, no-dementia, and Alzheimer's disease (AD) groups were then compared. RESULTS: The annual conversion rate of MCI to AD was 18.8%. Mean VR-I and VR-II baseline scores for MCI patients were 33.3 ± 5.6 and 20.5 ± 14.0, respectively. Mean VR-II scores for converted and nonconverted MCI patients were 7.2 ± 8.7 and 29.8 ± 9.3, respectively. CONCLUSIONS: It is likely that VR-II and VR-II/I scores are more sensitive for predicting conversion to AD in Japanese than in American MCI patients. Our results indicate that VR is a sensitive and useful measure for predicting the conversion of Japanese MCI patients to AD within 2 years.
Authors: B S Yogeetha; L M Haupt; K McKenzie; H G Sutherland; R K Okolicsyani; R A Lea; B H Maher; R C K Chan; D H K Shum; L R Griffiths Journal: Mol Biol Rep Date: 2013-08-06 Impact factor: 2.316
Authors: Yee Xing You; Nurul Fatin Malek Rivan; Devinder Kaur Ajit Singh; Nor Fadilah Rajab; Arimi Fitri Mat Ludin; Normah Che Din; Ai-Vyrn Chin; Michael Fenech; Mohd Zul Amin Kamaruddin; Suzana Shahar Journal: Int J Environ Res Public Health Date: 2022-07-22 Impact factor: 4.614