Literature DB >> 23403433

Activities of systemically administered echinocandins against in vivo mature Candida albicans biofilms developed in a rat subcutaneous model.

Sona Kucharíková1, Nidhi Sharma, Isabel Spriet, Johan Maertens, Patrick Van Dijck, Katrien Lagrou.   

Abstract

This study addresses the effects of micafungin, caspofungin, and anidulafungin against Candida albicans biofilms developed in a subcutaneous catheter rat model system. Doses of 5, 10, and 30 mg/kg (of body weight)/day (the last only for micafungin) were given intravenously for 5, 7, and 10 days. All three echinocandins caused a significant reduction of the Candida cell numbers on the implanted catheters and are thus promising for the treatment of biofilm-related infections.

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Year:  2013        PMID： 23403433      PMCID： PMC3632894          DOI： 10.1128/AAC.02288-12

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  14 in total

1.  Pharmacokinetics and tissue distribution of anidulafungin in rats.

Authors:  Bharat Damle; Martin Stogniew; James Dowell
Journal:  Antimicrob Agents Chemother       Date:  2008-04-28       Impact factor: 5.191

2.  Preliminary animal pharmacokinetics of the parenteral antifungal agent MK-0991 (L-743,872).

Authors:  R Hajdu; R Thompson; J G Sundelof; B A Pelak; F A Bouffard; J F Dropinski; H Kropp
Journal:  Antimicrob Agents Chemother       Date:  1997-11       Impact factor: 5.191

3.  In vitro activity of caspofungin against Candida albicans biofilms.

Authors:  Stefano P Bachmann; Kacy VandeWalle; Gordon Ramage; Thomas F Patterson; Brian L Wickes; John R Graybill; José L López-Ribot
Journal:  Antimicrob Agents Chemother       Date:  2002-11       Impact factor: 5.191

4.  Antifungal susceptibility of Candida biofilms: unique efficacy of amphotericin B lipid formulations and echinocandins.

Authors:  D M Kuhn; T George; J Chandra; P K Mukherjee; M A Ghannoum
Journal:  Antimicrob Agents Chemother       Date:  2002-06       Impact factor: 5.191

Review 5.  Pharmacokinetics/pharmacodynamics of echinocandins.

Authors:  U Theuretzbacher
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2004-10-14       Impact factor: 3.267

6.  In vivo efficacy of anidulafungin against mature Candida albicans biofilms in a novel rat model of catheter-associated Candidiasis.

Authors:  Sona Kucharíková; Hélène Tournu; Michelle Holtappels; Patrick Van Dijck; Katrien Lagrou
Journal:  Antimicrob Agents Chemother       Date:  2010-07-26       Impact factor: 5.191

7.  Tissue distribution after intravenous dosing of micafungin, an antifungal drug, to rats.

Authors:  Toshiro Niwa; Yoshiko Yokota; Akira Tokunaga; Yasuhiro Yamato; Akira Kagayama; Tomoichi Fujiwara; Junko Hatakeyama; Masaharu Anezaki; Yuko Ohtsuka; Akira Takagi
Journal:  Biol Pharm Bull       Date:  2004-07       Impact factor: 2.233

8.  Treatment and prevention of Candida albicans biofilms with caspofungin in a novel central venous catheter murine model of candidiasis.

Authors:  Anna L Lazzell; Ashok K Chaturvedi; Christopher G Pierce; Deepthi Prasad; Priya Uppuluri; Jose L Lopez-Ribot
Journal:  J Antimicrob Chemother       Date:  2009-07-07       Impact factor: 5.790

9.  Isolation of the Candida albicans gene for orotidine-5'-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations.

Authors:  A M Gillum; E Y Tsay; D R Kirsch
Journal:  Mol Gen Genet       Date:  1984

10.  Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America.

Authors:  Peter G Pappas; Carol A Kauffman; David Andes; Daniel K Benjamin; Thierry F Calandra; John E Edwards; Scott G Filler; John F Fisher; Bart-Jan Kullberg; Luis Ostrosky-Zeichner; Annette C Reboli; John H Rex; Thomas J Walsh; Jack D Sobel
Journal:  Clin Infect Dis       Date:  2009-03-01       Impact factor: 9.079
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  16 in total

Review 1.  Mechanisms of Candida biofilm drug resistance.

Authors:  Heather T Taff; Kaitlin F Mitchell; Jessica A Edward; David R Andes
Journal:  Future Microbiol       Date:  2013-10       Impact factor: 3.165

2.  Candida albicans biofilm development on medically-relevant foreign bodies in a mouse subcutaneous model followed by bioluminescence imaging.

Authors:  Soňa Kucharíková; Greetje Vande Velde; Uwe Himmelreich; Patrick Van Dijck
Journal:  J Vis Exp       Date:  2015-01-27       Impact factor: 1.355

3.  In vitro study of sequential fluconazole and caspofungin treatment against Candida albicans biofilms.

Authors:  Semanti Sarkar; Priya Uppuluri; Christopher G Pierce; Jose L Lopez-Ribot
Journal:  Antimicrob Agents Chemother       Date:  2013-11-11       Impact factor: 5.191

4.  Antifungal Activity of Oleylphosphocholine on In Vitro and In Vivo Candida albicans Biofilms.

Authors:  Michelle Holtappels; Erwin Swinnen; Lies De Groef; Jurgen Wuyts; Lieve Moons; Katrien Lagrou; Patrick Van Dijck; Soňa Kucharíková
Journal:  Antimicrob Agents Chemother       Date:  2017-12-21       Impact factor: 5.191

5.  High-content phenotypic screenings to identify inhibitors of Candida albicans biofilm formation and filamentation.

Authors:  Christopher G Pierce; Stephen P Saville; Jose L Lopez-Ribot
Journal:  Pathog Dis       Date:  2014-03-11       Impact factor: 3.166

6.  Pharmacodynamic and Immunomodulatory Effects of Micafungin on Host Responses against Biofilms of Candida parapsilosis in Comparison to Those of Candida albicans.

Authors:  Maria Simitsopoulou; Katerina Chlichlia; Daniela Kyrpitzi; Thomas J Walsh; Emmanuel Roilides
Journal:  Antimicrob Agents Chemother       Date:  2018-07-27       Impact factor: 5.191

Review 7.  Recent insights into Candida albicans biofilm resistance mechanisms.

Authors:  Lotte Mathé; Patrick Van Dijck
Journal:  Curr Genet       Date:  2013-08-25       Impact factor: 3.886

8.  Towards non-invasive monitoring of pathogen-host interactions during Candida albicans biofilm formation using in vivo bioluminescence.

Authors:  Greetje Vande Velde; Soňa Kucharíková; Sanne Schrevens; Uwe Himmelreich; Patrick Van Dijck
Journal:  Cell Microbiol       Date:  2013-09-12       Impact factor: 3.715

9.  Inhibitory Effect of Sophorolipid on Candida albicans Biofilm Formation and Hyphal Growth.

Authors:  Farazul Haque; Md Alfatah; K Ganesan; Mani Shankar Bhattacharyya
Journal:  Sci Rep       Date:  2016-03-31       Impact factor: 4.379

Review 10.  The Role of Antifungals against Candida Biofilm in Catheter-Related Candidemia.

Authors:  Emilio Bouza; Jesús Guinea; María Guembe
Journal:  Antibiotics (Basel)       Date:  2014-12-25
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