Literature DB >> 23402848

Into the valley of death: research to innovation.

John Hudson1, Hanan F Khazragui.   

Abstract

The phase between research and successful innovation is known as the valley of death. Increasingly, researchers from the pharmaceutical industry and academia are working together, often encouraged by governments, to cross this 'valley' as they seek to bring basic research to the market. This is consistent with newer models of innovation policy that stress interaction between the different agents across the innovation process. Here, we examine this interaction in the UK, the EU and the USA using several specific examples, suggesting that cooperation is still far from perfect and that the return for academia on its research investment is relatively small. Countries are also beginning to use research as a tool of industrial economic policy.
Copyright © 2013 Elsevier Ltd. All rights reserved.

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Year:  2013        PMID: 23402848     DOI: 10.1016/j.drudis.2013.01.012

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN: 1359-6446            Impact factor:   7.851


  9 in total

Review 1.  DNA microarray-based gene expression profiling of estrogenic chemicals.

Authors:  Ryoiti Kiyama; Yun Zhu
Journal:  Cell Mol Life Sci       Date:  2014-01-08       Impact factor: 9.261

2.  Corporate venture capital and Cambridge.

Authors:  Margaret G McCammon; Edwina Pio; Shima Barakat; Shailendra Vyakarnam
Journal:  Nat Biotechnol       Date:  2014-10       Impact factor: 54.908

3.  Data Augmentation and Transfer Learning to Improve Generalizability of an Automated Prostate Segmentation Model.

Authors:  Thomas H Sanford; Ling Zhang; Stephanie A Harmon; Jonathan Sackett; Dong Yang; Holger Roth; Ziyue Xu; Deepak Kesani; Sherif Mehralivand; Ronaldo H Baroni; Tristan Barrett; Rossano Girometti; Aytekin Oto; Andrei S Purysko; Sheng Xu; Peter A Pinto; Daguang Xu; Bradford J Wood; Peter L Choyke; Baris Turkbey
Journal:  AJR Am J Roentgenol       Date:  2020-10-14       Impact factor: 3.959

4.  The price of progress: Funding and financing Alzheimer's disease drug development.

Authors:  Jeffrey Cummings; Carl Reiber; Parvesh Kumar
Journal:  Alzheimers Dement (N Y)       Date:  2018-06-13

Review 5.  Metal Sulfide Nanoparticle Synthesis with Ionic Liquids - State of the Art and Future Perspectives.

Authors:  Christian Balischewski; Hyung-Seok Choi; Karsten Behrens; Alkit Beqiraj; Thomas Körzdörfer; André Geßner; Armin Wedel; Andreas Taubert
Journal:  ChemistryOpen       Date:  2021-02       Impact factor: 2.911

6.  Identification of β-Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions.

Authors:  Ben Gold; Jun Zhang; Landys Lopez Quezada; Julia Roberts; Yan Ling; Madeleine Wood; Wasima Shinwari; Laurent Goullieux; Christine Roubert; Laurent Fraisse; Eric Bacqué; Sophie Lagrange; Bruno Filoche-Rommé; Michal Vieth; Philip A Hipskind; Louis N Jungheim; Jeffrey Aubé; Sarah M Scarry; Stacey L McDonald; Kelin Li; Andrew Perkowski; Quyen Nguyen; Véronique Dartois; Matthew Zimmerman; David B Olsen; Katherine Young; Shilah Bonnett; Douglas Joerss; Tanya Parish; Helena I Boshoff; Kriti Arora; Clifton E Barry; Laura Guijarro; Sara Anca; Joaquín Rullas; Beatriz Rodríguez-Salguero; Maria S Martínez-Martínez; Esther Porras-De Francisco; Monica Cacho; David Barros-Aguirre; Paul Smith; Steven J Berthel; Carl Nathan; Robert H Bates
Journal:  ACS Infect Dis       Date:  2022-02-22       Impact factor: 5.084

7.  A novel maturity index for assessing medical device startups.

Authors:  Brian Green; Sowmya Lokappa; Katy Rudnick; Frances J Richmond; Grzegorz Zapotoczny; Juan Espinoza
Journal:  J Clin Transl Sci       Date:  2022-08-01

8.  Molecular genetics to genomic medicine practice: at the heart of value-based delivery of healthcare.

Authors:  Charis Eng
Journal:  Mol Genet Genomic Med       Date:  2013-05       Impact factor: 2.183

9.  Parallel universes of Black Six biology.

Authors:  Alexander Kraev
Journal:  Biol Direct       Date:  2014-07-19       Impact factor: 4.540

  9 in total

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