Literature DB >> 23399356

Ultrasonography-guided central venous catheterisation in haematological patients with severe thrombocytopenia.

Mariasanta Napolitano1, Alessandra Malato1, Francesco Raffaele2, Manuela Palazzolo2, Giorgio Lo Iacono2, Roberto Pinna2, Girolamo Geraci2, Giuseppe Modica2, Giorgia Saccullo1, Sergio Siragusa1, Massimo Cajozzo2.   

Abstract

BACKGROUND: Cannulation of the internal jugular vein (CVC) is a blind surface landmark-guided technique that could be potentially dangerous in patients with very low platelet counts. In such patients, ultrasonography (US)-guided CVC may be a valid approach. There is a lack of published data on the efficacy and safety of urgent US-guided CVC performed in haematological patients with severe thrombocytopenia.
MATERIALS AND METHODS: We retrospectively studied the safety of urgent CVC procedures in haematological patients including those with severe thrombocytopenia (platelet count <30×10(9)/L). From January 1999 to June 2009, 431 CVC insertional procedures in 431 consecutive patients were evaluated. Patients were included in the study if they had a haematological disorder and required urgent CVC insertion. Patients were placed in Trendelenburg's position, an 18-gauge needle and guide-wire were advanced under real-time US guidance into the last part of the internal jugular vein; central venous cannulation of the internal jugular vein was performed using the Seldinger technique in all the procedures. Major and minor procedure-related complications were recorded.
RESULTS: All 431 patients studied had haematological disorders: 39 had severe thrombocytopenia, refractory to platelet transfusion (group 1), while 392 did not have severe thrombocytopenia (group 2). The general characteristics of the patients in the two groups differed only for platelet count. The average time taken to perform the procedure was 4 minutes. Success rates were 97.4% and 97.9% in group 1 and group 2, respectively. No major complications occurred in either group. DISCUSSION: US-guided CVC is a safe and effective approach in haematological patients with severe thrombocytopenia requiring urgent cannulation for life support, plasma-exchange, chemotherapy and transfusion.

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Year:  2013        PMID: 23399356      PMCID: PMC3827393          DOI: 10.2450/2013.0129-12

Source DB:  PubMed          Journal:  Blood Transfus        ISSN: 1723-2007            Impact factor:   3.443


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  4 in total

Review 1.  Ultrasound-guided central vascular interventions, comments on the European Federation of Societies for Ultrasound in Medicine and Biology guidelines on interventional ultrasound.

Authors:  Christoph F Dietrich; Rudolf Horn; Susanne Morf; Liliana Chiorean; Yi Dong; Xin-Wu Cui; Nathan S S Atkinson; Christian Jenssen
Journal:  J Thorac Dis       Date:  2016-09       Impact factor: 2.895

Review 2.  Comparison of different platelet transfusion thresholds prior to insertion of central lines in patients with thrombocytopenia.

Authors:  Lise J Estcourt; Michael Desborough; Sally Hopewell; Carolyn Doree; Simon J Stanworth
Journal:  Cochrane Database Syst Rev       Date:  2015-12-02

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Authors:  Emma K van de Weerdt; Bart J Biemond; Sacha S Zeerleder; Krijn P van Lienden; Jan M Binnekade; Alexander P J Vlaar
Journal:  Trials       Date:  2018-02-20       Impact factor: 2.279

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Journal:  West J Emerg Med       Date:  2014-02
  4 in total

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