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Literature DB >> 23385957

Dual-channel electrospray microchip.

Yu Lu¹, Fang Liu, Niels Lion, Hubert H Girault.

Abstract

A dual-channel electrospray microchip has been developed for electrospray ionization mass spectrometry (ESI-MS) where aqueous samples are mixed at the Taylor cone with an organic buffer. Due to the fast and effective mixing in the Taylor cone, the aqueous sample can be well ionized with a high ion intensity. The influence of geometric parameters such as the distance between the two microchannels at their junction at the tip of the emitter has been investigated together with chemical parameters such as the organic buffer composition.

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Year: 2013 PMID： 23385957 DOI： 10.1007/s13361-012-0547-z

Source DB: PubMed Journal: J Am Soc Mass Spectrom ISSN： 1044-0305 Impact factor: 3.109

12 in total

Dual-channel electrospray microchip.

Review 1. Practical implications of some recent studies in electrospray ionization fundamentals.

2. Microfabricated polymer injector for direct mass spectrometry coupling.

3. On-chip protein sample desalting and preparation for direct coupling with electrospray ionization mass spectrometry.

4. Biphasic electrospray ionization for the study of interfacial complexes.

5. In-spray supercharging of peptides and proteins in electrospray ionization mass spectrometry.

6. Micro-electrospray mass spectrometry: Ultra-high-sensitivity analysis of peptides and proteins.

7. Microstructured photonic fibers as multichannel electrospray emitters.

8. Analytical properties of the nanoelectrospray ion source.

9. Peptide-phospholipid complex formation at liquid-liquid interfaces.

10. Microfabricated dual sprayer for on-line mass tagging of phosphopeptides.

1. Induced dual-nanospray: a novel internal calibration method for convenient and accurate mass measurement.

Review 2. Microfluidics-to-mass spectrometry: a review of coupling methods and applications.

3. Coaxial Electrospray Ionization for the Study of Rapid In-source Chemistry.

4. Multi-channel microfluidic chip coupling with mass spectrometry for simultaneous electro-sprays and extraction.