Literature DB >> 23381484

Brief report: is cognitive rehabilitation needed in verbal adults with autism? Insights from initial enrollment in a trial of cognitive enhancement therapy.

Shaun M Eack1, Amber L Bahorik, Susan S Hogarty, Deborah P Greenwald, Maralee Y Litschge, Carla A Mazefsky, Nancy J Minshew.   

Abstract

Cognitive rehabilitation is an emerging set of potentially effective interventions for the treatment of autism spectrum disorder, yet the applicability of these approaches for "high functioning" adults who have normative levels of intelligence remains unexplored. This study examined the initial cognitive performance characteristics of 40 verbal adults with autism enrolled in a pilot trial of Cognitive Enhancement Therapy to investigate the need for cognitive rehabilitation in this population. Results revealed marked and broad deficits across neurocognitive and social-cognitive domains, despite above-average IQ. Areas of greatest impairment included processing speed, cognitive flexibility, and emotion perception and management. These findings indicate the need for comprehensive interventions designed to enhance cognition among verbal adults with autism who have intact intellectual functioning.

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Year:  2013        PMID: 23381484      PMCID: PMC3686872          DOI: 10.1007/s10803-013-1774-2

Source DB:  PubMed          Journal:  J Autism Dev Disord        ISSN: 0162-3257


  15 in total

1.  Neuroprotective effects of cognitive enhancement therapy against gray matter loss in early schizophrenia: results from a 2-year randomized controlled trial.

Authors:  Shaun M Eack; Gerard E Hogarty; Raymond Y Cho; Konasale M R Prasad; Deborah P Greenwald; Susan S Hogarty; Matcheri S Keshavan
Journal:  Arch Gen Psychiatry       Date:  2010-05-03

2.  Follow-up study of eleven autistic children originally reported in 1943.

Authors:  L Kanner
Journal:  J Autism Child Schizophr       Date:  1971 Apr-Jun

3.  The autism diagnostic observation schedule-generic: a standard measure of social and communication deficits associated with the spectrum of autism.

Authors:  C Lord; S Risi; L Lambrecht; E H Cook; B L Leventhal; P C DiLavore; A Pickles; M Rutter
Journal:  J Autism Dev Disord       Date:  2000-06

4.  A meta-analysis of cognitive remediation for schizophrenia: methodology and effect sizes.

Authors:  Til Wykes; Vyv Huddy; Caroline Cellard; Susan R McGurk; Pál Czobor
Journal:  Am J Psychiatry       Date:  2011-03-15       Impact factor: 18.112

5.  Facial emotion recognition in schizophrenia: intensity effects and error pattern.

Authors:  Christian G Kohler; Travis H Turner; Warren B Bilker; Colleen M Brensinger; Steven J Siegel; Stephen J Kanes; Raquel E Gur; Ruben C Gur
Journal:  Am J Psychiatry       Date:  2003-10       Impact factor: 18.112

Review 6.  Approaching a consensus cognitive battery for clinical trials in schizophrenia: the NIMH-MATRICS conference to select cognitive domains and test criteria.

Authors:  Michael F Green; Keith H Nuechterlein; James M Gold; Deanna M Barch; Jonathan Cohen; Susan Essock; Wayne S Fenton; Fred Frese; Terry E Goldberg; Robert K Heaton; Richard S E Keefe; Robert S Kern; Helena Kraemer; Ellen Stover; Daniel R Weinberger; Steven Zalcman; Stephen R Marder
Journal:  Biol Psychiatry       Date:  2004-09-01       Impact factor: 13.382

7.  Cognitive enhancement therapy for schizophrenia: effects of a 2-year randomized trial on cognition and behavior.

Authors:  Gerard E Hogarty; Samuel Flesher; Richard Ulrich; Mary Carter; Deborah Greenwald; Michael Pogue-Geile; Matcheri Kechavan; Susan Cooley; Ann Louise DiBarry; Ann Garrett; Haranath Parepally; Rebecca Zoretich
Journal:  Arch Gen Psychiatry       Date:  2004-09

Review 8.  CNTRICS final task selection: social cognitive and affective neuroscience-based measures.

Authors:  Cameron S Carter; Deanna M Barch; Ruben Gur; Raquel Gur; Amy Pinkham; Kevin Ochsner
Journal:  Schizophr Bull       Date:  2008-11-14       Impact factor: 9.306

9.  Assessing social-cognitive deficits in schizophrenia with the Mayer-Salovey-Caruso Emotional Intelligence Test.

Authors:  Shaun M Eack; Catherine G Greeno; Michael F Pogue-Geile; Christina E Newhill; Gerard E Hogarty; Matcheri S Keshavan
Journal:  Schizophr Bull       Date:  2008-07-22       Impact factor: 9.306

Review 10.  New directions in behavioral treatment of autism spectrum disorders.

Authors:  Connie Kasari; Kathy Lawton
Journal:  Curr Opin Neurol       Date:  2010-04       Impact factor: 5.710

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  7 in total

1.  Repetitive Transcranial Magnetic Stimulation for the Treatment of Executive Function Deficits in Autism Spectrum Disorder: Clinical Trial Approach.

Authors:  Stephanie H Ameis; Zafiris J Daskalakis; Daniel M Blumberger; Pushpal Desarkar; Irene Drmic; Donald J Mabbott; Meng-Chuan Lai; Paul E Croarkin; Peter Szatmari
Journal:  J Child Adolesc Psychopharmacol       Date:  2017-03-27       Impact factor: 2.576

2.  Cognitive enhancement therapy for adult autism spectrum disorder: Results of an 18-month randomized clinical trial.

Authors:  Shaun M Eack; Susan S Hogarty; Deborah P Greenwald; Maralee Y Litschge; Shannondora A Porton; Carla A Mazefsky; Nancy J Minshew
Journal:  Autism Res       Date:  2017-12-29       Impact factor: 5.216

3.  Development of the Supported Employment, Comprehensive Cognitive Enhancement, and Social Skills program for adults on the autism spectrum: Results of initial study.

Authors:  Mary J Baker-Ericzén; Meghan A Fitch; Mikaela Kinnear; Melissa M Jenkins; Elizabeth W Twamley; Linda Smith; Gabriel Montano; Joshua Feder; Pamela J Crooke; Michelle G Winner; Juan Leon
Journal:  Autism       Date:  2017-10-14

4.  Processing Speed is Impaired in Adults with Autism Spectrum Disorder, and Relates to Social Communication Abilities.

Authors:  Sarah M Haigh; Jennifer A Walsh; Carla A Mazefsky; Nancy J Minshew; Shaun M Eack
Journal:  J Autism Dev Disord       Date:  2018-08

5.  Assessing Trial-to-Trial Variability in Auditory ERPs in Autism and Schizophrenia.

Authors:  Sarah M Haigh; Laura Van Key; Pat Brosseau; Shaun M Eack; David I Leitman; Dean F Salisbury; Marlene Behrmann
Journal:  J Autism Dev Disord       Date:  2022-10-07

6.  Misinterpretation of facial expressions of emotion in verbal adults with autism spectrum disorder.

Authors:  Shaun M Eack; Carla A Mazefsky; Nancy J Minshew
Journal:  Autism       Date:  2014-02-17

7.  Cognitive flexibility training intervention among children with autism: a longitudinal study.

Authors:  Cristina de Andrade Varanda; Fernanda Dreux Miranda Fernandes
Journal:  Psicol Reflex Crit       Date:  2017-07-25
  7 in total

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