Literature DB >> 23377371

Carbohydrate-containing Triton X-100 analogues for membrane protein solubilization and stabilization.

Pil Seok Chae1, Marc J Wander, Kyung Ho Cho, Philip D Laible, Samuel H Gellman.   

Abstract

Membrane protein manipulation is a challenging task owing to limited tertiary and quaternary structural stability once the protein has been removed from a lipid bilayer. Such instability can be overcome by embedding membrane proteins in detergent micelles formed from amphiphiles with carefully tuned properties. This study introduces a class of easy-to-synthesize amphiphiles, which are designated CGT (Chae's Glyco-Triton) detergents. Some of the agents are well suited for membrane protein solubilization and stabilization.

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Year:  2013        PMID： 23377371      PMCID： PMC3593792          DOI： 10.1039/c3mb25584k

Source DB:  PubMed          Journal:  Mol Biosyst        ISSN： 1742-2051


  45 in total

1.  Rigid Amphiphiles for Membrane Protein Manipulation.

Authors: 
Journal:  Angew Chem Int Ed Engl       Date:  2000-02       Impact factor: 15.336

2.  Lipopeptide detergents designed for the structural study of membrane proteins.

Authors:  Clare-Louise McGregor; Lu Chen; Neil C Pomroy; Peter Hwang; Sandy Go; Avijit Chakrabartty; Gilbert G Privé
Journal:  Nat Biotechnol       Date:  2003-01-13       Impact factor: 54.908

Review 3.  How many drug targets are there?

Authors:  John P Overington; Bissan Al-Lazikani; Andrew L Hopkins
Journal:  Nat Rev Drug Discov       Date:  2006-12       Impact factor: 84.694

4.  Tandem facial amphiphiles for membrane protein stabilization.

Authors:  Pil Seok Chae; Kamil Gotfryd; Jennifer Pacyna; Larry J W Miercke; Søren G F Rasmussen; Rebecca A Robbins; Rohini R Rana; Claus J Loland; Brian Kobilka; Robert Stroud; Bernadette Byrne; Ulrik Gether; Samuel H Gellman
Journal:  J Am Chem Soc       Date:  2010-11-04       Impact factor: 15.419

5.  The structure and catalytic cycle of a sodium-pumping pyrophosphatase.

Authors:  Juho Kellosalo; Tommi Kajander; Konstantin Kogan; Kisun Pokharel; Adrian Goldman
Journal:  Science       Date:  2012-07-27       Impact factor: 47.728

6.  A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins.

Authors:  Pil Seok Chae; Søren G F Rasmussen; Rohini R Rana; Kamil Gotfryd; Andrew C Kruse; Aashish Manglik; Kyung Ho Cho; Shailika Nurva; Ulrik Gether; Lan Guan; Claus J Loland; Bernadette Byrne; Brian K Kobilka; Samuel H Gellman
Journal:  Chemistry       Date:  2012-06-22       Impact factor: 5.236

7.  Calcium-regulated DNA binding and oligomerization of the neuronal calcium-sensing protein, calsenilin/DREAM/KChIP3.

Authors:  M Osawa; K I Tong; C Lilliehook; W Wasco; J D Buxbaum; H Y Cheng; J M Penninger; M Ikura; J B Ames
Journal:  J Biol Chem       Date:  2001-09-04       Impact factor: 5.157

Review 8.  Environmental fate of alkylphenols and alkylphenol ethoxylates--a review.

Authors:  Guang-Guo Ying; Brian Williams; Rai Kookana
Journal:  Environ Int       Date:  2002-07       Impact factor: 9.621

9.  Triton X-100 solubilization of mitochondrial inner and outer membranes.

Authors:  J I Gurtubay; F M Goñi; J C Gómez-Fernández; J J Otamendi; J M Macarulla
Journal:  J Bioenerg Biomembr       Date:  1980-04       Impact factor: 2.945

10.  Structure and dynamics of the M3 muscarinic acetylcholine receptor.

Authors:  Andrew C Kruse; Jianxin Hu; Albert C Pan; Daniel H Arlow; Daniel M Rosenbaum; Erica Rosemond; Hillary F Green; Tong Liu; Pil Seok Chae; Ron O Dror; David E Shaw; William I Weis; Jürgen Wess; Brian K Kobilka
Journal:  Nature       Date:  2012-02-22       Impact factor: 49.962
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  8 in total

1.  Novel tripod amphiphiles for membrane protein analysis.

Authors:  Pil Seok Chae; Andrew C Kruse; Kamil Gotfryd; Rohini R Rana; Kyung Ho Cho; Søren G F Rasmussen; Hyoung Eun Bae; Richa Chandra; Ulrik Gether; Lan Guan; Brian K Kobilka; Claus J Loland; Bernadette Byrne; Samuel H Gellman
Journal:  Chemistry       Date:  2013-10-02       Impact factor: 5.236

2.  Maltose neopentyl glycol-3 (MNG-3) analogues for membrane protein study.

Authors:  Kyung Ho Cho; Mohd Husri; Anowarul Amin; Kamil Gotfryd; Ho Jin Lee; Juyeon Go; Jin Woong Kim; Claus J Loland; Lan Guan; Bernadette Byrne; Pil Seok Chae
Journal:  Analyst       Date:  2015-03-27       Impact factor: 4.616

3.  1,3,5-Triazine-Cored Maltoside Amphiphiles for Membrane Protein Extraction and Stabilization.

Authors:  Lubna Ghani; Chastine F Munk; Xiang Zhang; Satoshi Katsube; Yang Du; Cristina Cecchetti; Weijiao Huang; Hyoung Eun Bae; Savvas Saouros; Muhammad Ehsan; Lan Guan; Xiangyu Liu; Claus J Loland; Brian K Kobilka; Bernadette Byrne; Pil Seok Chae
Journal:  J Am Chem Soc       Date:  2019-12-06       Impact factor: 15.419

4.  Novel Xylene-Linked Maltoside Amphiphiles (XMAs) for Membrane Protein Stabilisation.

Authors:  Kyung Ho Cho; Yang Du; Nicola J Scull; Parameswaran Hariharan; Kamil Gotfryd; Claus J Loland; Lan Guan; Bernadette Byrne; Brian K Kobilka; Pil Seok Chae
Journal:  Chemistry       Date:  2015-05-26       Impact factor: 5.236

5.  Hydrophobic variants of ganglio-tripod amphiphiles for membrane protein manipulation.

Authors:  Pil Seok Chae; Kyung Ho Cho; Marc J Wander; Hyoung Eun Bae; Samuel H Gellman; Philip D Laible
Journal:  Biochim Biophys Acta       Date:  2013-09-21

6.  Asymmetric maltose neopentyl glycol amphiphiles for a membrane protein study: effect of detergent asymmetricity on protein stability.

Authors:  Hyoung Eun Bae; Yang Du; Parameswaran Hariharan; Jonas S Mortensen; Kaavya K Kumar; Betty Ha; Manabendra Das; Hyun Sung Lee; Claus J Loland; Lan Guan; Brian K Kobilka; Pil Seok Chae
Journal:  Chem Sci       Date:  2018-11-05       Impact factor: 9.825

7.  A Class of Rigid Linker-bearing Glucosides for Membrane Protein Structural Study.

Authors:  Aiman Sadaf; Jonas S Mortensen; Stefano Capaldi; Elena Tikhonova; Parameswaran Hariharan; Orquidea de Castro Ribeiro; Claus J Loland; Lan Guan; Bernadette Byrne; Pil Seok Chae
Journal:  Chem Sci       Date:  2015-12-16       Impact factor: 9.825

8.  Dendronic trimaltoside amphiphiles (DTMs) for membrane protein study.

Authors:  Aiman Sadaf; Yang Du; Claudia Santillan; Jonas S Mortensen; Iago Molist; Alpay B Seven; Parameswaran Hariharan; Georgios Skiniotis; Claus J Loland; Brian K Kobilka; Lan Guan; Bernadette Byrne; Pil Seok Chae
Journal:  Chem Sci       Date:  2017-10-25       Impact factor: 9.825
  8 in total

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