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Literature DB >> 23371801

Selective fluorogenic chemosensors for distinct classes of nucleases.

Jong-Wha Jung¹, Sarah K Edwards, Eric T Kool.

Abstract

NUCLEASE SENSOR TRIO: Fluorogenic DNA sensors were developed for distinct classes of nucleases: 3'-exonucleases, 5'-exonucleases, and endonucleases. The highly selective sensors, built from very small modified DNA oligomers containing the unnatural fluorescent base pyrene, and employing thymine as a quencher, were found to function in a variety of complex biological media.

Entities: CellLine Chemical Disease Gene Species

Mesh：

Substances：

Year: 2013 PMID： 23371801 PMCID： PMC3770146 DOI： 10.1002/cbic.201300001

Source DB: PubMed Journal: Chembiochem ISSN： 1439-4227 Impact factor: 3.164

40 in total

1. Absence of muscarinic cholinergic airway responses in mice deficient in the cyclic nucleotide phosphodiesterase PDE4D.

Authors: G Hansen; S Jin; D T Umetsu; M Conti
Journal: Proc Natl Acad Sci U S A Date: 2000-06-06 Impact factor: 11.205

2. Gold nanoparticle based FRET assay for the detection of DNA cleavage.

Authors: Paresh Chandra Ray; Angela Fortner; Gopala Krishna Darbha
Journal: J Phys Chem B Date: 2006-10-26 Impact factor: 2.991

3. In situ, real-time monitoring of the 3' to 5' exonucleases secreted by living cells.

Authors: Xin Su; Xiaocui Zhu; Chen Zhang; Xianjin Xiao; Meiping Zhao
Journal: Anal Chem Date: 2012-05-14 Impact factor: 6.986

4. Nucleic acid-induced self-assembly of a platinum(II) terpyridyl complex: detection of G-quadruplex formation and nuclease activity.

Authors: Cong Yu; Kenneth Hoi-Yiu Chan; Keith Man-Chung Wong; Vivian Wing-Wah Yam
Journal: Chem Commun (Camb) Date: 2009-05-12 Impact factor: 6.222

5. DNA-polyfluorophore excimers as sensitive reporters for esterases and lipases.

Authors: Nan Dai; Yin Nah Teo; Eric T Kool
Journal: Chem Commun (Camb) Date: 2010-01-22 Impact factor: 6.222

6. Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes.

Authors: S A Ballard; C J Gingell; K Tang; L A Turner; M E Price; A M Naylor
Journal: J Urol Date: 1998-06 Impact factor: 7.450

Review 1. Fluorescent Probes of DNA Repair.

Authors: David L Wilson; Eric T Kool
Journal: ACS Chem Biol Date: 2017-11-30 Impact factor: 5.100

Review 2. Recent Advances in Nucleic Acid Targeting Probes and Supramolecular Constructs Based on Pyrene-Modified Oligonucleotides.

Authors: Olga A Krasheninina; Darya S Novopashina; Evgeny K Apartsin; Alya G Venyaminova
Journal: Molecules Date: 2017-11-30 Impact factor: 4.411

2 in total

Selective fluorogenic chemosensors for distinct classes of nucleases.

1. Absence of muscarinic cholinergic airway responses in mice deficient in the cyclic nucleotide phosphodiesterase PDE4D.

2. Gold nanoparticle based FRET assay for the detection of DNA cleavage.

3. In situ, real-time monitoring of the 3' to 5' exonucleases secreted by living cells.

4. Nucleic acid-induced self-assembly of a platinum(II) terpyridyl complex: detection of G-quadruplex formation and nuclease activity.

5. DNA-polyfluorophore excimers as sensitive reporters for esterases and lipases.

6. Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes.

7. A nuclease specific for heat-denatured DNA in isolated from a product of Aspergillus oryzae.

8. Positive inotropic effect of amrinone in relation to cyclic nucleotide metabolism in the canine ventricular muscle.

9. Oligodeoxyfluorosides: Strong Sequence Dependence of Fluorescence Emission.

10. RecJ exonuclease: substrates, products and interaction with SSB.

Review 1. Fluorescent Probes of DNA Repair.

Review 2. Recent Advances in Nucleic Acid Targeting Probes and Supramolecular Constructs Based on Pyrene-Modified Oligonucleotides.