| Literature DB >> 23371510 |
William G Sharp1, Rashelle C Berry, Courtney McCracken, Nadrat N Nuhu, Elizabeth Marvel, Celine A Saulnier, Ami Klin, Warren Jones, David L Jaquess.
Abstract
We conducted a comprehensive review and meta-analysis of research regarding feeding problems and nutrient status among children with autism spectrum disorders (ASD). The systematic search yielded 17 prospective studies involving a comparison group. Using rigorous meta-analysis techniques, we calculated the standardized mean difference (SMD) with standard error and corresponding odds ratio (OR) with 95 % confidence intervals (CI). Results indicated children with ASD experienced significantly more feeding problems versus peers, with an overall SMD of 0.89 (0.08) and a corresponding OR of 5.11, 95 % CI 3.74-6.97. Nutrient analyses indicated significantly lower intake of calcium (SMD: -0.65 [0.29]; OR: 0.31, 95 % CI 0.11-0.85) and protein (SMD: -0.58 [0.25]; OR: 0.35, 95 % CI: 0.14-0.56) in ASD. Future research must address critical questions regarding the cause, long-term impact, and remediation of atypical feeding in this population.Entities:
Mesh:
Year: 2013 PMID: 23371510 DOI: 10.1007/s10803-013-1771-5
Source DB: PubMed Journal: J Autism Dev Disord ISSN: 0162-3257