Literature DB >> 23360543

Asperterpenoid A, a new sesterterpenoid as an inhibitor of Mycobacterium tuberculosis protein tyrosine phosphatase B from the culture of Aspergillus sp. 16-5c.

Xishan Huang1, Hongbo Huang, Hanxiang Li, Xuefeng Sun, Huarong Huang, Yongjun Lu, Yongcheng Lin, Yuhua Long, Zhigang She.   

Abstract

Asperterpenoid A (1), a novel sesterterpenoid with a new carbon skeleton, has been isolated from a mangrove endophytic fungus Aspergillus sp. 16-5c. Its structure was characterized by extensive spectroscopic methods, and the absolute configuration was determined by single crystal X-ray diffraction analysis. Asperterpenoid A (1) exhibited strong inhibitory activity against Mycobacterium tuberculosis protein tyrosine phosphatase B (mPTPB) with an IC(50) value of 2.2 μM.

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Year:  2013        PMID： 23360543     DOI： 10.1021/ol303549c

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  24 in total

1.  Bioactive Metabolites from Mangrove Endophytic Fungus Aspergillus sp. 16-5B.

Authors:  Yayue Liu; Senhua Chen; Zhaoming Liu; Yongjun Lu; Guoping Xia; Hongju Liu; Lei He; Zhigang She
Journal:  Mar Drugs       Date:  2015-05-19       Impact factor: 5.118

Review 2.  Bioactive terpenes from marine-derived fungi.

Authors:  Ahmed M Elissawy; Mohamed El-Shazly; Sherif S Ebada; AbdelNasser B Singab; Peter Proksch
Journal:  Mar Drugs       Date:  2015-04-03       Impact factor: 5.118

3.  New depsidones and isoindolinones from the mangrove endophytic fungus Meyerozyma guilliermondii (HZ-Y2) isolated from the South China Sea.

Authors:  Senhua Chen; Zhaoming Liu; Yayue Liu; Yongjun Lu; Lei He; Zhigang She
Journal:  Beilstein J Org Chem       Date:  2015-07-16       Impact factor: 2.883

4.  New dimeric members of the phomoxanthone family: phomolactonexanthones A, B and deacetylphomoxanthone C isolated from the fungus Phomopsis sp.

Authors:  Bo Ding; Jie Yuan; Xishan Huang; Weitao Wen; Xu Zhu; Yayue Liu; Hanxiang Li; Yongjun Lu; Lei He; Hongmei Tan; Zhigang She
Journal:  Mar Drugs       Date:  2013-12-11       Impact factor: 5.118

5.  Eurothiocin A and B, sulfur-containing benzofurans from a soft coral-derived fungus Eurotium rubrum SH-823.

Authors:  Zhaoming Liu; Guoping Xia; Senhua Chen; Yayue Liu; Hanxiang Li; Zhigang She
Journal:  Mar Drugs       Date:  2014-06-20       Impact factor: 5.118

6.  Alterporriol-type dimers from the mangrove endophytic fungus, Alternaria sp. (SK11), and their MptpB inhibitions.

Authors:  Guoping Xia; Jia Li; Hanxiang Li; Yuhua Long; Shao'e Lin; Yongjun Lu; Lei He; Yongcheng Lin; Lan Liu; Zhigang She
Journal:  Mar Drugs       Date:  2014-05-16       Impact factor: 5.118

7.  Asperlones A and B, dinaphthalenone derivatives from a mangrove endophytic fungus Aspergillus sp. 16-5C.

Authors:  Ze'en Xiao; Shao'e Lin; Chunbing Tan; Yongjun Lu; Lei He; Xishan Huang; Zhigang She
Journal:  Mar Drugs       Date:  2015-01-13       Impact factor: 5.118

8.  Sesterterpene ophiobolin biosynthesis involving multiple gene clusters in Aspergillus ustus.

Authors:  Hangzhen Chai; Ru Yin; Yongfeng Liu; Huiying Meng; Xianqiang Zhou; Guolin Zhou; Xupeng Bi; Xue Yang; Tonghan Zhu; Weiming Zhu; Zixin Deng; Kui Hong
Journal:  Sci Rep       Date:  2016-06-07       Impact factor: 4.379

Review 9.  Advances in the study of the structures and bioactivities of metabolites isolated from mangrove-derived fungi in the South China Sea.

Authors:  Xin Wang; Zhi-Gang Mao; Bing-Bing Song; Chun-Hua Chen; Wei-Wei Xiao; Bin Hu; Ji-Wen Wang; Xiao-Bing Jiang; Yong-Hong Zhu; Hai-Jun Wang
Journal:  Mar Drugs       Date:  2013-09-30       Impact factor: 5.118

10.  Isolation, Structural Characterization and Antidiabetic Activity of New Diketopiperazine Alkaloids from Mangrove Endophytic Fungus Aspergillus sp. 16-5c.

Authors:  Geting Ye; Cuiying Huang; Jialin Li; Tao Chen; Jing Tang; Wenbin Liu; Yuhua Long
Journal:  Mar Drugs       Date:  2021-07-20       Impact factor: 5.118
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