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Literature DB >> 23360291

Synthesis of biotinylated c-di-gmp and c-di-amp using click conjugation.

Barbara L Gaffney¹, Nicholas D Stebbins, Roger A Jones.

Abstract

The biotinylated c-di-GMP and c-di-AMP conjugates 10a/b were synthesized by a straightforward set of procedures from standard, commercially available phosphoramidites. Their availability should allow isolation and characterization of new protein and RNA receptors for these key bacterial signaling molecules.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2013 PMID： 23360291 PMCID： PMC3561633 DOI： 10.1080/15257770.2012.748196

Source DB: PubMed Journal: Nucleosides Nucleotides Nucleic Acids ISSN： 1525-7770 Impact factor: 1.381

32 in total

1. Great times for small molecules: c-di-AMP, a second messenger candidate in Bacteria and Archaea.

Authors: Ute Römling
Journal: Sci Signal Date: 2008-08-19 Impact factor: 8.192

Review 2. Sensing the messenger: the diverse ways that bacteria signal through c-di-GMP.

Authors: Petya Violinova Krasteva; Krista Michelle Giglio; Holger Sondermann
Journal: Protein Sci Date: 2012-06-05 Impact factor: 6.725

3. Bacterial c-di-GMP is an immunostimulatory molecule.

Authors: David K R Karaolis; Terry K Means; De Yang; Munehisa Takahashi; Teizo Yoshimura; Eric Muraille; Dana Philpott; John T Schroeder; Mamoru Hyodo; Yoshihiro Hayakawa; Brian G Talbot; Eric Brouillette; François Malouin
Journal: J Immunol Date: 2007-02-15 Impact factor: 5.422

4. Polymorphism of the signaling molecule c-di-GMP.

Authors: Zhaoying Zhang; Seho Kim; Barbara L Gaffney; Roger A Jones
Journal: J Am Chem Soc Date: 2006-05-31 Impact factor: 15.419

Review 5. Principles of c-di-GMP signalling in bacteria.

Authors: Regine Hengge
Journal: Nat Rev Microbiol Date: 2009-04 Impact factor: 60.633

Review 6. Structural and mechanistic determinants of c-di-GMP signalling.

Authors: Tilman Schirmer; Urs Jenal
Journal: Nat Rev Microbiol Date: 2009-10 Impact factor: 60.633

7. Structural biochemistry of a bacterial checkpoint protein reveals diadenylate cyclase activity regulated by DNA recombination intermediates.

Authors: Gregor Witte; Sophia Hartung; Katharina Büttner; Karl-Peter Hopfner
Journal: Mol Cell Date: 2008-04-25 Impact factor: 17.970

Synthesis of biotinylated c-di-gmp and c-di-amp using click conjugation.

1. Great times for small molecules: c-di-AMP, a second messenger candidate in Bacteria and Archaea.

Review 2. Sensing the messenger: the diverse ways that bacteria signal through c-di-GMP.

3. Bacterial c-di-GMP is an immunostimulatory molecule.

4. Polymorphism of the signaling molecule c-di-GMP.

Review 5. Principles of c-di-GMP signalling in bacteria.

Review 6. Structural and mechanistic determinants of c-di-GMP signalling.

7. Structural biochemistry of a bacterial checkpoint protein reveals diadenylate cyclase activity regulated by DNA recombination intermediates.

8. Riboswitches in eubacteria sense the second messenger cyclic di-GMP.

Review 9. The growing applications of click chemistry.

Review 10. 'Life-style' control networks in Escherichia coli: signaling by the second messenger c-di-GMP.

1. Catalytic Promiscuity of cGAS: A Facile Enzymatic Synthesis of 2'-3'-Linked Cyclic Dinucleotides.