Literature DB >> 23359702

Second act: Drug repurposing gets a boost as academic researchers join the search for novel uses of existing drugs.

Prashant Nair.   

Abstract

Mesh：

Year:  2013        PMID： 23359702      PMCID： PMC3574921          DOI： 10.1073/pnas.201300188

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  7 in total

1.  Algorithm discovery by protein folding game players.

Authors:  Firas Khatib; Seth Cooper; Michael D Tyka; Kefan Xu; Ilya Makedon; Zoran Popovic; David Baker; Foldit Players
Journal:  Proc Natl Acad Sci U S A       Date:  2011-11-07       Impact factor: 11.205

2.  The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.

Authors:  Justin Lamb; Emily D Crawford; David Peck; Joshua W Modell; Irene C Blat; Matthew J Wrobel; Jim Lerner; Jean-Philippe Brunet; Aravind Subramanian; Kenneth N Ross; Michael Reich; Haley Hieronymus; Guo Wei; Scott A Armstrong; Stephen J Haggarty; Paul A Clemons; Ru Wei; Steven A Carr; Eric S Lander; Todd R Golub
Journal:  Science       Date:  2006-09-29       Impact factor: 47.728

3.  Straight talk with...Mac Cowell and Jason Bobe. Interview by Prashant Nair.

Authors:  Mac Cowell; Jason Bobe
Journal:  Nat Med       Date:  2009-03       Impact factor: 53.440

Review 4.  Exploiting drug-disease relationships for computational drug repositioning.

Authors:  Joel T Dudley; Tarangini Deshpande; Atul J Butte
Journal:  Brief Bioinform       Date:  2011-06-20       Impact factor: 11.622

5.  Discovery and preclinical validation of drug indications using compendia of public gene expression data.

Authors:  Marina Sirota; Joel T Dudley; Jeewon Kim; Annie P Chiang; Alex A Morgan; Alejandro Sweet-Cordero; Julien Sage; Atul J Butte
Journal:  Sci Transl Med       Date:  2011-08-17       Impact factor: 17.956

6.  Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease.

Authors:  Joel T Dudley; Marina Sirota; Mohan Shenoy; Reetesh K Pai; Silke Roedder; Annie P Chiang; Alex A Morgan; Minnie M Sarwal; Pankaj Jay Pasricha; Atul J Butte
Journal:  Sci Transl Med       Date:  2011-08-17       Impact factor: 17.956

7.  Endothelin-1 is elevated in Alzheimer's disease and upregulated by amyloid-β.

Authors:  Jennifer C Palmer; Rachel Barker; Patrick G Kehoe; Seth Love
Journal:  J Alzheimers Dis       Date:  2012       Impact factor: 4.472
  7 in total
  6 in total

1.  Overcoming Drug Development Bottlenecks With Repurposing: Old drugs learn new tricks.

Authors:  Stephen M Strittmatter
Journal:  Nat Med       Date:  2014-06       Impact factor: 53.440

Review 2.  Using Big Data to Discover Diagnostics and Therapeutics for Gastrointestinal and Liver Diseases.

Authors:  Benjamin Wooden; Nicolas Goossens; Yujin Hoshida; Scott L Friedman
Journal:  Gastroenterology       Date:  2016-10-20       Impact factor: 33.883

Review 3.  Biomarker-guided repurposing of chemotherapeutic drugs for cancer therapy: a novel strategy in drug development.

Authors:  Jan Stenvang; Iben Kümler; Sune Boris Nygård; David Hersi Smith; Dorte Nielsen; Nils Brünner; José M A Moreira
Journal:  Front Oncol       Date:  2013-12-25       Impact factor: 6.244

4.  Pathway analysis for drug repositioning based on public database mining.

Authors:  Yongmei Pan; Tiejun Cheng; Yanli Wang; Stephen H Bryant
Journal:  J Chem Inf Model       Date:  2014-02-05       Impact factor: 4.956

5.  Identification of MALT1 as both a prognostic factor and a potential therapeutic target of regorafenib in cholangiocarcinoma patients.

Authors:  Chun-Nan Yeh; Yu-Chan Chang; Yeu Su; Dennis Shin-Shian Hsu; Chi-Tung Cheng; Ren-Chin Wu; Yi-Hsiu Chung; Kun-Chun Chiang; Ta-Sen Yeh; Meng-Lun Lu; Chun-Yu Liu; Peter Mu-Hsin Chang; Ming-Han Chen; Chi-Ying F Huang; Michael Hsiao; Ming-Huang Chen
Journal:  Oncotarget       Date:  2017-12-08

6.  Fighting viruses with antibiotics: an overlooked path.

Authors:  Philippe Colson; Didier Raoult
Journal:  Int J Antimicrob Agents       Date:  2016-08-05       Impact factor: 5.283
  6 in total

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