OBJECTIVES: The authors sought to study the characteristics and outcomes of patients with contralateral carotid artery occlusions (CCOs) undergoing elective carotid artery stenting (CAS). BACKGROUND: CCOs are associated with adverse neurological events following carotid endarterectomy. METHODS: In-hospital outcomes were examined in patients with and without CCO undergoing elective CAS in the Carotid Artery Revascularization and Endarterectomy (CARE) registry. A CCO was defined as a 100% occlusion of the contralateral internal carotid artery. To minimize differences in measured comorbidities, a 3:1 propensity matching analysis was performed comparing 42 clinical and demographic variables between CCO and non-CCO patients from the CARE registry. The primary endpoint was a composite of in-hospital death, nonfatal myocardial infarction, and nonfatal stroke. RESULTS: Between April 2005 and January 2012, 13,993 eligible patients underwent elective CAS, of whom 1,450 (10%) had CCO. There were 5,500 CAS procedures (1,375 CCO and 4,125 non-CCO) identified in the propensity analysis. The primary composite endpoint occurred in 29 (2.1%) and 107 (2.6%) patients with and without CCO, respectively (adjusted odds ratio: 0.81, 95% confidence interval: 0.53 to 1.23, p = 0.316). CONCLUSIONS: In the CARE registry, there was no evidence that the presence of a CCO was associated with an increased risk of in-hospital death, nonfatal myocardial infarction, or nonfatal stroke in patients undergoing elective CAS. These findings may have implications on the selection of carotid revascularization procedures for such patients.
OBJECTIVES: The authors sought to study the characteristics and outcomes of patients with contralateral carotid artery occlusions (CCOs) undergoing elective carotid artery stenting (CAS). BACKGROUND: CCOs are associated with adverse neurological events following carotid endarterectomy. METHODS: In-hospital outcomes were examined in patients with and without CCO undergoing elective CAS in the Carotid Artery Revascularization and Endarterectomy (CARE) registry. A CCO was defined as a 100% occlusion of the contralateral internal carotid artery. To minimize differences in measured comorbidities, a 3:1 propensity matching analysis was performed comparing 42 clinical and demographic variables between CCO and non-CCOpatients from the CARE registry. The primary endpoint was a composite of in-hospital death, nonfatal myocardial infarction, and nonfatal stroke. RESULTS: Between April 2005 and January 2012, 13,993 eligible patients underwent elective CAS, of whom 1,450 (10%) had CCO. There were 5,500 CAS procedures (1,375 CCO and 4,125 non-CCO) identified in the propensity analysis. The primary composite endpoint occurred in 29 (2.1%) and 107 (2.6%) patients with and without CCO, respectively (adjusted odds ratio: 0.81, 95% confidence interval: 0.53 to 1.23, p = 0.316). CONCLUSIONS: In the CARE registry, there was no evidence that the presence of a CCO was associated with an increased risk of in-hospital death, nonfatal myocardial infarction, or nonfatal stroke in patients undergoing elective CAS. These findings may have implications on the selection of carotid revascularization procedures for such patients.
Authors: Alejandro González; Jose Ramón González-Marcos; Eva Martínez; Fernando Boza; Aurelio Cayuela; Antonio Mayol; Alberto Gil-Peralta Journal: Cerebrovasc Dis Date: 2005-12-02 Impact factor: 2.762
Authors: Christopher J White; Surendra B Avula; Randy T Mintz; Ayman Iskander; Arun Chervu; Robert L Feldman; Marc L Schermerhorn; Henry H Woo; L Nelson Hopkins Journal: Catheter Cardiovasc Interv Date: 2011-10-05 Impact factor: 2.692
Authors: A Mathur; G S Roubin; C R Gomez; S S Iyer; P M Wong; C Piamsomboon; S S Yadav; L S Dean; J J Vitek Journal: Am J Cardiol Date: 1998-06-01 Impact factor: 2.778
Authors: Anna K Krawisz; Kenneth Rosenfield; Christopher J White; Michael R Jaff; Joseph Campbell; Kevin Kennedy; Thomas Tsai; Beau Hawkins; Schuyler Jones; Eric A Secemsky Journal: J Am Coll Cardiol Date: 2021-02-23 Impact factor: 24.094