Literature DB >> 23345907

Energy landscape and dynamics of biomolecules extended abstract.

Hans Frauenfelder1.   

Abstract

Proteins are not isolated homogeneous systems. Each protein can exist in a very large number of conformations (conformational substates) that are characterized by an energy landscape. The main conformational motions, similar to the α and β fluctuations in glasses, are linked to fluctuations in the bulk solvent and the hydration shell.

Keywords:  alpha and beta relaxations; protein dynamics; protein energy landscape; protein fluctuations; slaving

Year:  2005        PMID： 23345907      PMCID： PMC3456333          DOI： 10.1007/s10867-005-0696-4

Source DB:  PubMed          Journal:  J Biol Phys        ISSN： 0092-0606            Impact factor:   1.365


  11 in total

1.  Solvent effects on conformational dynamics of Zn-substituted myoglobin observed by time-resolved hole-burning spectroscopy.

Authors:  Y Shibata; A Kurita; T Kushida
Journal:  Biochemistry       Date:  1999-02-09       Impact factor: 3.162

2.  Slaving: solvent fluctuations dominate protein dynamics and functions.

Authors:  P W Fenimore; H Frauenfelder; B H McMahon; F G Parak
Journal:  Proc Natl Acad Sci U S A       Date:  2002-11-20       Impact factor: 11.205

3.  Glassy behavior of a protein.

Authors: 
Journal:  Phys Rev Lett       Date:  1989-04-17       Impact factor: 9.161

4.  Mosaic energy landscapes of liquids and the control of protein conformational dynamics by glass-forming solvents.

Authors:  Vassiliy Lubchenko; Peter G Wolynes; Hans Frauenfelder
Journal:  J Phys Chem B       Date:  2005-04-21       Impact factor: 2.991

5.  The energy landscapes and motions of proteins.

Authors:  H Frauenfelder; S G Sligar; P G Wolynes
Journal:  Science       Date:  1991-12-13       Impact factor: 47.728

6.  Relaxation behavior in atomic and molecular glasses.

Authors: 
Journal:  Phys Rev B Condens Matter       Date:  1990-02-01

7.  Solvent composition and viscosity effects on the kinetics of CO binding to horse myoglobin.

Authors:  T Kleinert; W Doster; H Leyser; W Petry; V Schwarz; M Settles
Journal:  Biochemistry       Date:  1998-01-13       Impact factor: 3.162

8.  Temperature-dependent X-ray diffraction as a probe of protein structural dynamics.

Authors:  H Frauenfelder; G A Petsko; D Tsernoglou
Journal:  Nature       Date:  1979-08-16       Impact factor: 49.962

9.  Protein states and proteinquakes.

Authors:  A Ansari; J Berendzen; S F Bowne; H Frauenfelder; I E Iben; T B Sauke; E Shyamsunder; R D Young
Journal:  Proc Natl Acad Sci U S A       Date:  1985-08       Impact factor: 11.205

10.  Dynamics of ligand binding to myoglobin.

Authors:  R H Austin; K W Beeson; L Eisenstein; H Frauenfelder; I C Gunsalus
Journal:  Biochemistry       Date:  1975-12-02       Impact factor: 3.162
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  3 in total

1.  Temperature and solvent dependence of the dynamical landscape of tau protein conformations.

Authors:  Antonio Bianconi; Gabriele Ciasca; Alexander Tenenbaum; Anna Battisti; Gaetano Campi
Journal:  J Biol Phys       Date:  2011-11-16       Impact factor: 1.365

2.  Fitness landscapes for coupled map lattices.

Authors:  Noelle Driver; Michael Frame
Journal:  J Biol Phys       Date:  2021-09-08       Impact factor: 1.560

3.  Methodological notes on pandemic virus SARS-CoV-2 research.

Authors:  Gianluigi Zangari Del Balzo
Journal:  Theory Biosci       Date:  2021-09-08       Impact factor: 1.919
  3 in total

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