Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Isolation of fatty acid amide as an angiogenic principle from bovine mesentery.

Literature DB >> 2334413

Isolation of fatty acid amide as an angiogenic principle from bovine mesentery.

K Wakamatsu¹, T Masaki, F Itoh, K Kondo, K Sudo.

Abstract

Erucamide (13-docosenamide) was found to be the major bovine mesentery angiogenic lipid as assessed by chorioallantoic membrane (CAM) assay. Two micrograms of this lipid caused angiogenesis in the assay. Angiogenic activity of this naturally occurring lipid was also found by rat corneal micropocket and mouse dorsal air-sac assays. Specificity of the chemical structure which elicited activity was low, however. The mechanism of angiogenic activity is unknown and this lipid does not promote proliferation of endothelial cells or induce inflammatory effects.

Entities: Chemical Species

Mesh：

Substances：

Year: 1990 PMID： 2334413 DOI： 10.1016/0006-291x(90)92338-z

Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575

Keyword Cloud
Cited

15 in total

1. Endocannabinoid-like N-arachidonoyl serine is a novel pro-angiogenic mediator.

Authors: X Zhang; Y Maor; J F Wang; G Kunos; J E Groopman
Journal: Br J Pharmacol Date: 2010-08 Impact factor: 8.739

Review 2. Biosynthesis, degradation and pharmacological importance of the fatty acid amides.

Authors: Emma K Farrell; David J Merkler
Journal: Drug Discov Today Date: 2008-04-03 Impact factor: 7.851

3. Chemical requirements for inhibition of gap junction communication by the biologically active lipid oleamide.

Authors: D L Boger; J E Patterson; X Guan; B F Cravatt; R A Lerner; N B Gilula
Journal: Proc Natl Acad Sci U S A Date: 1998-04-28 Impact factor: 11.205

4. Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide.

Authors: D L Boger; H Sato; A E Lerner; M P Hedrick; R A Fecik; H Miyauchi; G D Wilkie; B J Austin; M P Patricelli; B F Cravatt
Journal: Proc Natl Acad Sci U S A Date: 2000-05-09 Impact factor: 11.205

Review 5. Fatty acid amide signaling molecules.

Authors: Cyrine Ezzili; Katerina Otrubova; Dale L Boger
Journal: Bioorg Med Chem Lett Date: 2010-08-13 Impact factor: 2.823

6. Structural requirements for 5-HT2A and 5-HT1A serotonin receptor potentiation by the biologically active lipid oleamide.

Authors: D L Boger; J E Patterson; Q Jin
Journal: Proc Natl Acad Sci U S A Date: 1998-04-14 Impact factor: 11.205

Isolation of fatty acid amide as an angiogenic principle from bovine mesentery.

1. Endocannabinoid-like N-arachidonoyl serine is a novel pro-angiogenic mediator.

Review 2. Biosynthesis, degradation and pharmacological importance of the fatty acid amides.

3. Chemical requirements for inhibition of gap junction communication by the biologically active lipid oleamide.

4. Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide.

Review 5. Fatty acid amide signaling molecules.

6. Structural requirements for 5-HT2A and 5-HT1A serotonin receptor potentiation by the biologically active lipid oleamide.

7. Molecular characterization of human and mouse fatty acid amide hydrolases.

8. Primary fatty acid amide metabolism: conversion of fatty acids and an ethanolamine in N18TG2 and SCP cells.

9. Erucamide as a modulator of water balance: new function of a fatty acid amide.

10. Stimulation of nitrogen removal in the rhizosphere of aquatic duckweed by root exudate components.