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Literature DB >> 20817522

Fatty acid amide signaling molecules.

Cyrine Ezzili¹, Katerina Otrubova, Dale L Boger.

Abstract

Key studies leading to the discovery and definition of the role of endogenous fatty acid amide signaling molecules are summarized.

Entities: CellLine Chemical Disease Gene Species

Mesh：

Substances：
Amides
Fatty Acids

Year: 2010 PMID： 20817522 PMCID： PMC2942981 DOI： 10.1016/j.bmcl.2010.08.048

Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823

191 in total

1. Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide.

Authors: P M Zygmunt; J Petersson; D A Andersson; H Chuang; M Sørgård; V Di Marzo; D Julius; E D Högestätt
Journal: Nature Date: 1999-07-29 Impact factor: 49.962

2. Differential regulation of peptide alpha-amidation by dexamethasone and disulfiram.

Authors: W J Driscoll; S A Mueller; B A Eipper; G P Mueller
Journal: Mol Pharmacol Date: 1999-06 Impact factor: 4.436

3. The endogenous lipid oleamide activates serotonin 5-HT7 neurons in mouse thalamus and hypothalamus.

Authors: E A Thomas; B F Cravatt; J G Sutcliffe
Journal: J Neurochem Date: 1999-06 Impact factor: 5.372

4. Analogues and homologues of N-palmitoylethanolamide, a putative endogenous CB(2) cannabinoid, as potential ligands for the cannabinoid receptors.

Authors: D M Lambert; F G DiPaolo; P Sonveaux; M Kanyonyo; S J Govaerts; E Hermans; J Bueb; N M Delzenne; E J Tschirhart
Journal: Biochim Biophys Acta Date: 1999-09-22

Review 5. Metabolism of anandamide and 2-arachidonoylglycerol: an historical overview and some recent developments.

Authors: V Di Marzo; L De Petrocellis; T Bisogno; D Melck
Journal: Lipids Date: 1999 Impact factor: 1.880

Review 6. The palmitoylethanolamide and oleamide enigmas : are these two fatty acid amides cannabimimetic?

Authors: D M Lambert; V Di Marzo
Journal: Curr Med Chem Date: 1999-08 Impact factor: 4.530

Review 7. Discovery and characterization of endogenous cannabinoids.

Authors: B R Martin; R Mechoulam; R K Razdan
Journal: Life Sci Date: 1999 Impact factor: 5.037

Review 8. Cannabimimetic fatty acid derivatives: the anandamide family and other endocannabinoids.

Authors: V Di Marzo; T Bisogno; L De Petrocellis; D Melck; B R Martin
Journal: Curr Med Chem Date: 1999-08 Impact factor: 4.530

Review 9. Pharmacology of cannabinoid receptor ligands.

Authors: R G Pertwee
Journal: Curr Med Chem Date: 1999-08 Impact factor: 4.530

10. Pain modulation by release of the endogenous cannabinoid anandamide.

Authors: J M Walker; S M Huang; N M Strangman; K Tsou; M C Sañudo-Peña
Journal: Proc Natl Acad Sci U S A Date: 1999-10-12 Impact factor: 11.205

33 in total

1. Structural basis for the acyltransferase activity of lecithin:retinol acyltransferase-like proteins.

Authors: Marcin Golczak; Philip D Kiser; Avery E Sears; David T Lodowski; William S Blaner; Krzysztof Palczewski
Journal: J Biol Chem Date: 2012-05-17 Impact factor: 5.157

2. Modulation of Glucagon-like Peptide-1 (GLP-1) Potency by Endocannabinoid-like Lipids Represents a Novel Mode of Regulating GLP-1 Receptor Signaling.

Authors: Yu-Hong Cheng; Mei-Shang Ho; Wei-Ting Huang; Ying-Ting Chou; Klim King
Journal: J Biol Chem Date: 2015-04-22 Impact factor: 5.157

3. Discovery of PF-04457845: A Highly Potent, Orally Bioavailable, and Selective Urea FAAH Inhibitor.

Authors: Douglas S Johnson; Cory Stiff; Scott E Lazerwith; Suzanne R Kesten; Lorraine K Fay; Mark Morris; David Beidler; Marya B Liimatta; Sarah E Smith; David T Dudley; Nalini Sadagopan; Shobha N Bhattachar; Stephen J Kesten; Tyzoon K Nomanbhoy; Benjamin F Cravatt; Kay Ahn
Journal: ACS Med Chem Lett Date: 2011-02-10 Impact factor: 4.345

Review 4. The discovery and development of inhibitors of fatty acid amide hydrolase (FAAH).

Authors: Katerina Otrubova; Cyrine Ezzili; Dale L Boger
Journal: Bioorg Med Chem Lett Date: 2011-06-28 Impact factor: 2.823

5. Preclinical Characterization of the FAAH Inhibitor JNJ-42165279.

Authors: John M Keith; William M Jones; Mark Tichenor; Jing Liu; Mark Seierstad; James A Palmer; Michael Webb; Mark Karbarz; Brian P Scott; Sandy J Wilson; Lin Luo; Michelle L Wennerholm; Leon Chang; Michele Rizzolio; Raymond Rynberg; Sandra R Chaplan; J Guy Breitenbucher
Journal: ACS Med Chem Lett Date: 2015-11-02 Impact factor: 4.345

6. Fluoride-mediated capture of a noncovalent bound state of a reversible covalent enzyme inhibitor: X-ray crystallographic analysis of an exceptionally potent α-ketoheterocycle inhibitor of fatty acid amide hydrolase.

Authors: Mauro Mileni; Joie Garfunkle; Cyrine Ezzili; Benjamin F Cravatt; Raymond C Stevens; Dale L Boger
Journal: J Am Chem Soc Date: 2011-02-28 Impact factor: 15.419

7. Saccharin induced liver inflammation in mice by altering the gut microbiota and its metabolic functions.

Authors: Xiaoming Bian; Pengcheng Tu; Liang Chi; Bei Gao; Hongyu Ru; Kun Lu
Journal: Food Chem Toxicol Date: 2017-05-01 Impact factor: 6.023

8. Rational design of fatty acid amide hydrolase inhibitors that act by covalently bonding to two active site residues.

Authors: Katerina Otrubova; Monica Brown; Michael S McCormick; Gye W Han; Scott T O'Neal; Benjamin F Cravatt; Raymond C Stevens; Aron H Lichtman; Dale L Boger
Journal: J Am Chem Soc Date: 2013-04-12 Impact factor: 15.419

9. Lipidomics profile of a NAPE-PLD KO mouse provides evidence of a broader role of this enzyme in lipid metabolism in the brain.

Authors: Emma Leishman; Ken Mackie; Serge Luquet; Heather B Bradshaw
Journal: Biochim Biophys Acta Date: 2016-03-05

10. Discovery libraries targeting the major enzyme classes: the serine hydrolases.

Authors: Katerina Otrubova; Venkat Srinivasan; Dale L Boger
Journal: Bioorg Med Chem Lett Date: 2014-06-27 Impact factor: 2.823