Literature DB >> 23335811

Carbene Complexes in the Synthesis of Complex Natural Products: Total Synthesis of the Calphostins.

Craig A Merlic1, Courtney C Aldrich, Jennifer Albaneze-Walker, Alan Saghatelian.   

Abstract

Entities:  

Year:  2000        PMID: 23335811      PMCID: PMC3548573          DOI: 10.1021/ja994313+

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


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  9 in total

1.  Inhibition of protein kinase C by calphostin C is light-dependent.

Authors:  R F Bruns; F D Miller; R L Merriman; J J Howbert; W F Heath; E Kobayashi; I Takahashi; T Tamaoki; H Nakano
Journal:  Biochem Biophys Res Commun       Date:  1991-04-15       Impact factor: 3.575

2.  Studies and prospectives of the protein kinase c family for cellular regulation.

Authors:  Y Nishizuka
Journal:  Cancer       Date:  1989-05-15       Impact factor: 6.860

Review 3.  The potential for isoenzyme-selective modulation of protein kinase C.

Authors:  J Hofmann
Journal:  FASEB J       Date:  1997-07       Impact factor: 5.191

4.  UCN-1028A, a novel and specific inhibitor of protein kinase C, from Cladosporium.

Authors:  E Kobayashi; K Ando; H Nakano; T Tamaoki
Journal:  J Antibiot (Tokyo)       Date:  1989-01       Impact factor: 2.649

5.  Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C.

Authors:  E Kobayashi; H Nakano; M Morimoto; T Tamaoki
Journal:  Biochem Biophys Res Commun       Date:  1989-03-15       Impact factor: 3.575

Review 6.  Naturally occurring perylenequinones.

Authors:  U Weiss; L Merlini; G Nasini
Journal:  Fortschr Chem Org Naturst       Date:  1987

7.  Calphostins, novel and specific inhibitors of protein kinase C. II. Chemical structures.

Authors:  T Iida; E Kobayashi; M Yoshida; H Sano
Journal:  J Antibiot (Tokyo)       Date:  1989-10       Impact factor: 2.649

8.  Calphostins (UCN-1028), novel and specific inhibitors of protein kinase C. I. Fermentation, isolation, physico-chemical properties and biological activities.

Authors:  E Kobayashi; K Ando; H Nakano; T Iida; H Ohno; M Morimoto; T Tamaoki
Journal:  J Antibiot (Tokyo)       Date:  1989-10       Impact factor: 2.649

Review 9.  Therapeutic potential of protein kinase C inhibitors.

Authors:  D Bradshaw; C H Hill; J S Nixon; S E Wilkinson
Journal:  Agents Actions       Date:  1993-01
  9 in total
  6 in total

1.  Perylenequinone natural products: evolution of the total synthesis of cercosporin.

Authors:  Barbara J Morgan; Carol A Mulrooney; Marisa C Kozlowski
Journal:  J Org Chem       Date:  2010-01-01       Impact factor: 4.354

2.  Perylenequinone natural products: enantioselective synthesis of the oxidized pentacyclic core.

Authors:  Carol A Mulrooney; Barbara J Morgan; Xiaolin Li; Marisa C Kozlowski
Journal:  J Org Chem       Date:  2010-01-01       Impact factor: 4.354

3.  Perylenequinone natural products: total syntheses of the diastereomers (+)-phleichrome and (+)-calphostin D by assembly of centrochiral and axial chiral fragments.

Authors:  Barbara J Morgan; Carol A Mulrooney; Erin M O'Brien; Marisa C Kozlowski
Journal:  J Org Chem       Date:  2010-01-01       Impact factor: 4.354

4.  Perylenequinone natural products: total synthesis of hypocrellin A.

Authors:  Erin M O'Brien; Barbara J Morgan; Carol A Mulrooney; Patrick J Carroll; Marisa C Kozlowski
Journal:  J Org Chem       Date:  2010-01-01       Impact factor: 4.354

5.  Design, synthesis, and investigation of protein kinase C inhibitors: total syntheses of (+)-calphostin D, (+)-phleichrome, cercosporin, and new photoactive perylenequinones.

Authors:  Barbara J Morgan; Sangeeta Dey; Steven W Johnson; Marisa C Kozlowski
Journal:  J Am Chem Soc       Date:  2009-07-08       Impact factor: 15.419

6.  Perylenequinones: Isolation, Synthesis, and Biological Activity.

Authors:  Carol A Mulrooey; Erin M O'Brien; Barbara J Morgan; Marisa C Kozlowski
Journal:  European J Org Chem       Date:  2012-07-01
  6 in total

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