| Literature DB >> 23327523 |
Anne B C Cherry1, George Q Daley.
Abstract
The conversion of somatic cells into pluripotent cells is transforming the way diseases are researched and treated. Induced pluripotent stem (iPS) cells' promise may soon be realized in the field of hematology, as hematopoietic stem cell transplants are already commonplace in clinics around the world. We provide a current comparison between induced pluripotent and embryonic stem cells, describe progress toward modeling hematological disorders using iPS cells, and illustrate the hurdles that must be overcome before iPS cell therapies will be available in clinics.Entities:
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Year: 2013 PMID: 23327523 PMCID: PMC3629705 DOI: 10.1146/annurev-med-050311-163324
Source DB: PubMed Journal: Annu Rev Med ISSN: 0066-4219 Impact factor: 13.739