Literature DB >> 23326156

Tumor-infiltrating B cells come into vogue.

Michael Linnebacher1.   

Abstract

Lymphocyte infiltration into solid tumors has been recognized as a main determinator of positive prognosis. For the most part this is attributed to cytotoxic T cells capable of directly destroying malignant cells. However, when considering the complex composition of the human immune system, recent findings of Nielsen et al on a potentially central role of tumor-infiltrating B cells is not really surprising. In this commentary article, I want to highlight the enormous potential impact of this observation for basic and translational research, prognostic procedures and ultimately for the development of future therapeutic concepts.

Entities:  

Keywords:  CD20+ tumor-infiltrating lymphocytes; Functional immunology; Immunotherapy; Prognosis; Tumor-infiltrating B cells

Mesh：

Substances：

Year:  2013        PMID： 23326156      PMCID： PMC3542760          DOI： 10.3748/wjg.v19.i1.8

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN： 1007-9327            Impact factor:   5.742


  25 in total

1.  Tumor-infiltrating B cell immunoglobulin variable region gene usage in invasive ductal breast carcinoma.

Authors:  Peter Simsa; Jean-Luc Teillaud; David I Stott; József Tóth; Beatrix Kotlan
Journal:  Pathol Oncol Res       Date:  2005-07-01       Impact factor: 3.201

2.  Novel ganglioside antigen identified by B cells in human medullary breast carcinomas: the proof of principle concerning the tumor-infiltrating B lymphocytes.

Authors:  Beatrix Kotlan; Peter Simsa; Jean-Luc Teillaud; Wolf Herman Fridman; Jozsef Toth; Michael McKnight; Mark C Glassy
Journal:  J Immunol       Date:  2005-08-15       Impact factor: 5.422

Review 3.  CD20+ B cells: the other tumor-infiltrating lymphocytes.

Authors:  Brad H Nelson
Journal:  J Immunol       Date:  2010-11-01       Impact factor: 5.422

4.  B lymphocytes promote lymphogenous metastasis of lymphoma and melanoma.

Authors:  Alanna Ruddell; Maria I Harrell; Momoko Furuya; Sara B Kirschbaum; Brian M Iritani
Journal:  Neoplasia       Date:  2011-08       Impact factor: 5.715

5.  Cryopreservation of human colorectal carcinomas prior to xenografting.

Authors:  Michael Linnebacher; Claudia Maletzki; Christiane Ostwald; Ulrike Klier; Mathias Krohn; Ernst Klar; Friedrich Prall
Journal:  BMC Cancer       Date:  2010-07-08       Impact factor: 4.430

6.  The humoral immune system has a key prognostic impact in node-negative breast cancer.

Authors:  Marcus Schmidt; Daniel Böhm; Christian von Törne; Eric Steiner; Alexander Puhl; Henryk Pilch; Hans-Anton Lehr; Jan G Hengstler; Heinz Kölbl; Mathias Gehrmann
Journal:  Cancer Res       Date:  2008-07-01       Impact factor: 12.701

7.  Microsatellite instability in colorectal cancer is associated with local lymphocyte infiltration and low frequency of distant metastases.

Authors:  A Buckowitz; H-P Knaebel; A Benner; H Bläker; J Gebert; P Kienle; M von Knebel Doeberitz; M Kloor
Journal:  Br J Cancer       Date:  2005-05-09       Impact factor: 7.640

8.  Distribution of immune cells in head and neck cancer: CD8+ T-cells and CD20+ B-cells in metastatic lymph nodes are associated with favourable outcome in patients with oro- and hypopharyngeal carcinoma.

Authors:  Dominik Pretscher; Luitpold V Distel; Gerhard G Grabenbauer; Michael Wittlinger; Maike Buettner; Gerald Niedobitek
Journal:  BMC Cancer       Date:  2009-08-22       Impact factor: 4.430

9.  Tumor-infiltrating B cells: The ignored players in tumor immunology.

Authors:  Michael Linnebacher; Claudia Maletzki
Journal:  Oncoimmunology       Date:  2012-10-01       Impact factor: 8.110

10.  Tumor-infiltrating B lymphocytes as an efficient source of highly specific immunoglobulins recognizing tumor cells.

Authors:  Emiliano Pavoni; Giorgia Monteriù; Daniela Santapaola; Fiorella Petronzelli; Anna Maria Anastasi; Angela Pelliccia; Valeria D'Alessio; Rita De Santis; Olga Minenkova
Journal:  BMC Biotechnol       Date:  2007-10-18       Impact factor: 2.563
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  9 in total

1.  Plasma cells in primary melanoma. Prognostic significance and possible role of IgA.

Authors:  Francesca M Bosisio; James S Wilmott; Nathalie Volders; Marjorie Mercier; Jasper Wouters; Marguerite Stas; Willeke Am Blokx; Daniela Massi; John F Thompson; Richard A Scolyer; Nicolas van Baren; Joost J van den Oord
Journal:  Mod Pathol       Date:  2016-02-12       Impact factor: 7.842

2.  Advanced Proteogenomic Analysis Reveals Multiple Peptide Mutations and Complex Immunoglobulin Peptides in Colon Cancer.

Authors:  Sunghee Woo; Seong Won Cha; Stefano Bonissone; Seungjin Na; David L Tabb; Pavel A Pevzner; Vineet Bafna
Journal:  J Proteome Res       Date:  2015-07-21       Impact factor: 4.466

Review 3.  B cell-regulated immune responses in tumor models and cancer patients.

Authors:  Carlo Fremd; Florian Schuetz; Christof Sohn; Philipp Beckhove; Christoph Domschke
Journal:  Oncoimmunology       Date:  2013-07-01       Impact factor: 8.110

4.  Gene landscape and correlation between B-cell infiltration and programmed death ligand 1 expression in lung adenocarcinoma patients from The Cancer Genome Atlas data set.

Authors:  Kuo-Hao Ho; Chih-Ju Chang; Tzu-Wen Huang; Chwen-Ming Shih; Ann-Jeng Liu; Peng-Hsu Chen; Kur-Ta Cheng; Ku-Chung Chen
Journal:  PLoS One       Date:  2018-12-06       Impact factor: 3.240

Review 5.  Checkpoint molecules on infiltrating immune cells in colorectal tumor microenvironment.

Authors:  Iman M Talaat; Noha M Elemam; Shroque Zaher; Maha Saber-Ayad
Journal:  Front Med (Lausanne)       Date:  2022-08-22

6.  Upregulation of EMID1 Accelerates to a Favorable Prognosis and Immune Infiltration in Lung Adenocarcinoma.

Authors:  Yufeng Shao; Zhong Zheng; Sen Li; Guangyu Yang; Fuwei Qi; Fan Fei
Journal:  J Oncol       Date:  2022-09-19       Impact factor: 4.501

7.  Tumor infiltrating B-cells are increased in prostate cancer tissue.

Authors:  Jason R Woo; Michael A Liss; Michelle T Muldong; Kerrin Palazzi; Amy Strasner; Massimo Ammirante; Nissi Varki; Ahmed Shabaik; Stephen Howell; Christopher J Kane; Michael Karin; Christina A M Jamieson
Journal:  J Transl Med       Date:  2014-01-30       Impact factor: 5.531

8.  Comparative study of various subpopulations of cytotoxic cells in blood and ascites from patients with ovarian carcinoma.

Authors:  Sarka Lukesova; Vladimira Vroblova; Jindrich Tosner; Jindrich Kopecky; Iva Sedlakova; Eva Čermáková; Doris Vokurkova; Otakar Kopecky
Journal:  Contemp Oncol (Pozn)       Date:  2015-09-18

9.  Tumor-infiltrating B cells producing antitumor active immunoglobulins in resected HCC prolong patient survival.

Authors:  Stefan M Brunner; Timo Itzel; Christoph Rubner; Rebecca Kesselring; Eva Griesshammer; Matthias Evert; Andreas Teufel; Hans J Schlitt; Stefan Fichtner-Feigl
Journal:  Oncotarget       Date:  2017-08-09
  9 in total

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