| Literature DB >> 23318987 |
C Letellier1, F Denis, L A Aguirre.
Abstract
A simple model of three competing cell populations (host, immune and tumor cells) is revisited by using a topological analysis and computing observability coefficients. Our aim is to show that a non-conventional analysis might suggest new trends in understanding the interactions of some tumor cells and their environment. The action of some parameter values on the resulting dynamics is investigated. Our results are related to some clinical features, suggesting that this model thus captures relevant phenomena to cell interactions.Entities:
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Year: 2013 PMID: 23318987 DOI: 10.1016/j.jtbi.2013.01.003
Source DB: PubMed Journal: J Theor Biol ISSN: 0022-5193 Impact factor: 2.691