Literature DB >> 23316878

Treatment of obsessive-compulsive disorder complicated by comorbid eating disorders.

H Blair Simpson1, Chad T Wetterneck, Shawn P Cahill, Joanna E Steinglass, Martin E Franklin, Rachel C Leonard, Theodore E Weltzin, Bradley C Riemann.   

Abstract

PURPOSE: Eating disorders and obsessive-compulsive disorder (OCD) commonly co-occur, but there is little data for how to treat these complex cases. To address this gap, we examined the naturalistic outcome of 56 patients with both disorders, who received a multimodal treatment program designed to address both problems simultaneously.
METHODS: A residential treatment program developed a cognitive-behavioral approach for patients with both OCD and an eating disorder by integrating exposure and response prevention (ERP) treatment for OCD with ERP strategies targeting eating pathology. Patients also received a supervised eating plan, medication management, and social support. At admission and discharge, patients completed validated measures of OCD severity (the Yale-Brown Obsessive-Compulsive Scale--Self Report [Y-BOCS-SR]), eating disorder severity (the Eating Disorders Examination-Questionnaire), and depressive severity (the Beck Depression Inventory II [BDI-II]). Body mass index (BMI) was also measured. Paired-sample t-tests examined change on these measures. MAIN
RESULTS: Between 2006 and 2011, 56 individuals completed all study measures at admission and discharge. Mean length of stay was 57 days (SD = 27). Most (89%) were on psychiatric medications. Significant decreases were observed in OCD severity, eating disorder severity, and depression. Those with bulimia nervosa showed more improvement than those with anorexia nervosa. BMI significantly increased, primarily among those underweight at admission.
CONCLUSION: Simultaneous treatment of OCD and eating disorders using a multimodal approach that emphasizes ERP techniques for both OCD and eating disorders can be an effective treatment strategy for these complex cases.

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Year:  2013        PMID: 23316878      PMCID: PMC3947513          DOI: 10.1080/16506073.2012.751124

Source DB:  PubMed          Journal:  Cogn Behav Ther        ISSN: 1650-6073


  39 in total

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3.  Fear of food as a treatment target: exposure and response prevention for anorexia nervosa in an open series.

Authors:  Joanna Steinglass; Anne Marie Albano; H Blair Simpson; Kenneth Carpenter; Janet Schebendach; Evelyn Attia
Journal:  Int J Eat Disord       Date:  2011-05-03       Impact factor: 4.861

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Review 6.  Rationale for the application of exposure and response prevention to the treatment of anorexia nervosa.

Authors:  Joanna E Steinglass; Robyn Sysko; Deborah Glasofer; Anne Marie Albano; H Blair Simpson; B Timothy Walsh
Journal:  Int J Eat Disord       Date:  2011-03       Impact factor: 4.861

7.  Obsessive-compulsive severity spectrum in the community: prevalence, comorbidity, and course.

Authors:  Jules Angst; Alex Gamma; Jerome Endrass; Renee Goodwin; Vladeta Ajdacic; Dominique Eich; Wulf Rössler
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2004-06       Impact factor: 5.270

8.  Differential response to placebo among patients with social phobia, panic disorder, and obsessive-compulsive disorder.

Authors:  Jonathan D Huppert; Luke T Schultz; Edna B Foa; David H Barlow; Jonathan R T Davidson; Jack M Gorman; M Katherine Shear; H Blair Simpson; Scott W Woods
Journal:  Am J Psychiatry       Date:  2004-08       Impact factor: 18.112

9.  Treatment of depressive and obsessive-compulsive symptoms in OCD by imipramine and behaviour therapy.

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Journal:  Br J Clin Psychol       Date:  1992-09

10.  Bulimia nervosa: group behavior therapy with exposure plus response prevention.

Authors:  J J Gray; C M Hoage
Journal:  Psychol Rep       Date:  1990-04
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  7 in total

1.  Pharmacotherapeutic Considerations in the Treatment of an Adolescent with Anorexia Nervosa and Obsessive Compulsive Disorder.

Authors:  Timothy Rice; Barbara J Coffey
Journal:  J Child Adolesc Psychopharmacol       Date:  2015-06       Impact factor: 2.576

2.  Associations between dimensions of anorexia nervosa and obsessive-compulsive disorder: An examination of personality and psychological factors in patients with anorexia nervosa.

Authors:  Cheri A Levinson; Stephanie C Zerwas; Leigh C Brosof; Laura M Thornton; Michael Strober; Bernadette Pivarunas; James J Crowley; Zeynep Yilmaz; Wade H Berrettini; Harry Brandt; Steven Crawford; Manfred M Fichter; Katherine A Halmi; Craig Johnson; Allan S Kaplan; Maria La Via; James Mitchell; Alessandro Rotondo; D Blake Woodside; Walter H Kaye; Cynthia M Bulik
Journal:  Eur Eat Disord Rev       Date:  2018-08-22

3.  Confronting fear using exposure and response prevention for anorexia nervosa: A randomized controlled pilot study.

Authors:  Joanna E Steinglass; Anne Marie Albano; H Blair Simpson; Yuanjia Wang; Jingjing Zou; Evelyn Attia; B Timothy Walsh
Journal:  Int J Eat Disord       Date:  2013-11-08       Impact factor: 4.861

Review 4.  The clinical basis of orthorexia nervosa: emerging perspectives.

Authors:  Nancy S Koven; Alexandra W Abry
Journal:  Neuropsychiatr Dis Treat       Date:  2015-02-18       Impact factor: 2.570

Review 5.  Psychiatric and medical comorbidities of eating disorders: findings from a rapid review of the literature.

Authors:  Ashlea Hambleton; Genevieve Pepin; Anvi Le; Danielle Maloney; Stephen Touyz; Sarah Maguire
Journal:  J Eat Disord       Date:  2022-09-05

6.  Dissection of the Genetic Association between Anorexia Nervosa and Obsessive-Compulsive Disorder at the Network and Cellular Levels.

Authors:  Weichen Song; Weidi Wang; Shunying Yu; Guan Ning Lin
Journal:  Genes (Basel)       Date:  2021-03-27       Impact factor: 4.096

7.  Obsessive-compulsive symptoms in young women affected with anorexia nervosa, and their relationship with personality, psychopathology, and attachment style.

Authors:  Federico Amianto; Ilaria Secci; Luca Arletti; Chiara Davico; Giovanni Abbate Daga; Benedetto Vitiello
Journal:  Eat Weight Disord       Date:  2021-06-30       Impact factor: 4.652

  7 in total

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