Literature DB >> 23312455

Comparison of the mechanisms responsible for cervical remodeling in preterm and term labor.

Juan M Gonzalez1, Roberto Romero, Guillermina Girardi.   

Abstract

Understanding the mechanisms of term and preterm cervical remodeling is essential to prevent prematurity. Is preterm cervical remodeling caused by the same mechanisms that cause cervical remodeling at term, and are these changes accelerated in time? This question has been pondered by obstetricians seeking strategies to prevent preterm labor for many years. Mice represent an informative model of preterm birth. Thus, in this review we discuss the recent findings from mouse models that identify and characterize the initiators and cellular effectors of cervical remodeling at term and preterm labor/delivery. These studies suggest that similarities and differences exist between term and preterm cervical remodeling. Complement is an initiator or mediator in preterm labor/delivery, but is not involved in the physiological process that leads to term delivery. Therefore, complememt constitutes a specific and selective target for potentially preventing preterm delivery, thus improving neonatal health.
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

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Year:  2013        PMID： 23312455      PMCID： PMC3581722          DOI： 10.1016/j.jri.2012.07.008

Source DB:  PubMed          Journal:  J Reprod Immunol        ISSN： 0165-0378            Impact factor:   4.054


  51 in total

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Journal:  Obstet Gynecol       Date:  1991-07       Impact factor: 7.661

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Journal:  Fertil Steril       Date:  1990-12       Impact factor: 7.329

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Journal:  N Engl J Med       Date:  1996-02-29       Impact factor: 91.245
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  26 in total

1.  Effect of depth on shear-wave elastography estimated in the internal and external cervical os during pregnancy.

Authors:  Edgar Hernandez-Andrade; Alma Aurioles-Garibay; Maynor Garcia; Steven J Korzeniewski; Alyse G Schwartz; Hyunyoung Ahn; Alicia Martinez-Varea; Lami Yeo; Tinnakorn Chaiworapongsa; Sonia S Hassan; Roberto Romero
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Review 2.  Interferons and Proinflammatory Cytokines in Pregnancy and Fetal Development.

Authors:  Laura J Yockey; Akiko Iwasaki
Journal:  Immunity       Date:  2018-09-18       Impact factor: 31.745

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Authors:  Edgar Hernandez-Andrade; Maynor Garcia; Hyunyoung Ahn; Steven J Korzeniewski; Homam Saker; Lami Yeo; Tinnakorn Chaiworapongsa; Sonia S Hassan; Roberto Romero
Journal:  J Perinat Med       Date:  2015-11       Impact factor: 1.901

4.  Cervical strain determined by ultrasound elastography and its association with spontaneous preterm delivery.

Authors:  Edgar Hernandez-Andrade; Roberto Romero; Steven J Korzeniewski; Hyunyoung Ahn; Alma Aurioles-Garibay; Maynor Garcia; Alyse G Schwartz; Lami Yeo; Tinnakorn Chaiworapongsa; Sonia S Hassan
Journal:  J Perinat Med       Date:  2014-03       Impact factor: 1.901

5.  Distinct reorganization of collagen architecture in lipopolysaccharide-mediated premature cervical remodeling.

Authors:  Shanmugasundaram Nallasamy; Meredith Akins; Breanna Tetreault; Kate Luby-Phelps; Mala Mahendroo
Journal:  Biol Reprod       Date:  2018-01-01       Impact factor: 4.285

Review 6.  The complement system and adverse pregnancy outcomes.

Authors:  Jean F Regal; Jeffrey S Gilbert; Richard M Burwick
Journal:  Mol Immunol       Date:  2015-03-21       Impact factor: 4.407

7.  Pregnancy-specific transcriptional changes upon endotoxin exposure in mice.

Authors:  Kenichiro Motomura; Roberto Romero; Adi L Tarca; Jose Galaz; Gaurav Bhatti; Bogdan Done; Marcia Arenas-Hernandez; Dustyn Levenson; Rebecca Slutsky; Chaur-Dong Hsu; Nardhy Gomez-Lopez
Journal:  J Perinat Med       Date:  2020-09-25       Impact factor: 1.901

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Authors:  Hae-Ryung Park; Sean M Harris; Erica Boldenow; Richard C McEachin; Maureen Sartor; Mark Chames; Rita Loch-Caruso
Journal:  Biol Reprod       Date:  2018-03-01       Impact factor: 4.285

9.  Density of Stromal Cells and Macrophages Associated With Collagen Remodeling in the Human Cervix in Preterm and Term Birth.

Authors:  Aurelija Dubicke; Gunvor Ekman-Ordeberg; Patricia Mazurek; Lindsay Miller; Steven M Yellon
Journal:  Reprod Sci       Date:  2015-11-25       Impact factor: 3.060

10.  Vaginal progesterone to prevent preterm birth in pregnant women with a sonographic short cervix: clinical and public health implications.

Authors:  Agustin Conde-Agudelo; Roberto Romero
Journal:  Am J Obstet Gynecol       Date:  2015-10-09       Impact factor: 8.661
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