Literature DB >> 23312031

One protein, at least three structures, and many functions.

Adam Zlotnick1, Zhenning Tan2, Lisa Selzer2.   

Abstract

Hepatitis B virus core gene products can adopt different conformations to perform their functional roles. In this issue of Structure, DiMattia and colleagues show the crystal structure of immuno-modulating HBeAg and thereby reveal the similarities and differences between it and HBcAg, the variant found in virions.
Copyright © 2013 Elsevier Ltd. All rights reserved.

Entities:  

Year:  2013        PMID： 23312031      PMCID： PMC3545281          DOI： 10.1016/j.str.2012.12.003

Source DB:  PubMed          Journal:  Structure        ISSN： 0969-2126            Impact factor:   5.006


  9 in total

1.  The mechanism of an immature secretion phenotype of a highly frequent naturally occurring missense mutation at codon 97 of human hepatitis B virus core antigen.

Authors:  T T Yuan; G K Sahu; W E Whitehead; R Greenberg; C Shih
Journal:  J Virol       Date:  1999-07       Impact factor: 5.103

2.  The crystal structure of the human hepatitis B virus capsid.

Authors:  S A Wynne; R A Crowther; A G Leslie
Journal:  Mol Cell       Date:  1999-06       Impact factor: 17.970

3.  Low-level secretion of human hepatitis B virus virions caused by two independent, naturally occurring mutations (P5T and L60V) in the capsid protein.

Authors:  S Le Pogam; T T Yuan; G K Sahu; S Chatterjee; C Shih
Journal:  J Virol       Date:  2000-10       Impact factor: 5.103

4.  Role of the propeptide in controlling conformation and assembly state of hepatitis B virus e-antigen.

Authors:  Norman R Watts; James F Conway; Naiqian Cheng; Stephen J Stahl; Alasdair C Steven; Paul T Wingfield
Journal:  J Mol Biol       Date:  2011-04-02       Impact factor: 5.469

5.  Immune tolerance split between hepatitis B virus precore and core proteins.

Authors:  Margaret Chen; Matti Sällberg; Janice Hughes; Joyce Jones; Luca G Guidotti; Francis V Chisari; Jean-Noel Billaud; David R Milich
Journal:  J Virol       Date:  2005-03       Impact factor: 5.103

6.  Conformational changes in the hepatitis B virus core protein are consistent with a role for allostery in virus assembly.

Authors:  Charles Packianathan; Sarah P Katen; Charles E Dann; Adam Zlotnick
Journal:  J Virol       Date:  2009-11-25       Impact factor: 5.103

7.  Hepatitis B virus capsid assembly is enhanced by naturally occurring mutation F97L.

Authors:  Pablo Ceres; Stephen J Stray; Adam Zlotnick
Journal:  J Virol       Date:  2004-09       Impact factor: 5.103

8.  A mutant hepatitis B virus core protein mimics inhibitors of icosahedral capsid self-assembly.

Authors:  Christina R Bourne; Sarah P Katen; Matthew R Fulz; Charles Packianathan; Adam Zlotnick
Journal:  Biochemistry       Date:  2009-03-03       Impact factor: 3.162

9.  Antigenic switching of hepatitis B virus by alternative dimerization of the capsid protein.

Authors:  Michael A DiMattia; Norman R Watts; Stephen J Stahl; Jonathan M Grimes; Alasdair C Steven; David I Stuart; Paul T Wingfield
Journal:  Structure       Date:  2012-12-06       Impact factor: 5.006
  9 in total
  8 in total

1.  The interface between hepatitis B virus capsid proteins affects self-assembly, pregenomic RNA packaging, and reverse transcription.

Authors:  Zhenning Tan; Karolyn Pionek; Nuruddin Unchwaniwala; Megan L Maguire; Daniel D Loeb; Adam Zlotnick
Journal:  J Virol       Date:  2015-01-07       Impact factor: 5.103

2.  Assessment of differences in the conformational flexibility of hepatitis B virus core-antigen and e-antigen by hydrogen deuterium exchange-mass spectrometry.

Authors:  Jessica Z Bereszczak; Norman R Watts; Paul T Wingfield; Alasdair C Steven; Albert J R Heck
Journal:  Protein Sci       Date:  2014-04-17       Impact factor: 6.725

3.  Monitoring Assembly of Virus Capsids with Nanofluidic Devices.

Authors:  Zachary D Harms; Lisa Selzer; Adam Zlotnick; Stephen C Jacobson
Journal:  ACS Nano       Date:  2015-08-26       Impact factor: 15.881

4.  Structures of Hepatitis B Virus Core- and e-Antigen Immune Complexes Suggest Multi-point Inhibition.

Authors:  Elif Eren; Norman R Watts; Altaira D Dearborn; Ira W Palmer; Joshua D Kaufman; Alasdair C Steven; Paul T Wingfield
Journal:  Structure       Date:  2018-08-09       Impact factor: 5.006

Review 5.  Assembly and Release of Hepatitis B Virus.

Authors:  Lisa Selzer; Adam Zlotnick
Journal:  Cold Spring Harb Perspect Med       Date:  2015-11-09       Impact factor: 6.915

6.  Production of the HBc Protein from Different HBV Genotypes in E. coli. Use of Reassociated HBc VLPs for Packaging of ss- and dsRNA.

Authors:  Ivars Petrovskis; Ilva Lieknina; Andris Dislers; Juris Jansons; Janis Bogans; Inara Akopjana; Jelena Zakova; Irina Sominskaya
Journal:  Microorganisms       Date:  2021-01-30

Review 7.  The regenerating protein 3A: a crucial molecular with dual roles in cancer.

Authors:  Liying Wang; Yanchun Quan; Yanxi Zhu; Xiaoli Xie; Zhiqiang Wang; Long Wang; Xiuhong Wei; Fengyuan Che
Journal:  Mol Biol Rep       Date:  2021-11-23       Impact factor: 2.316

8.  The hepatitis B virus core protein intradimer interface modulates capsid assembly and stability.

Authors:  Lisa Selzer; Sarah P Katen; Adam Zlotnick
Journal:  Biochemistry       Date:  2014-08-18       Impact factor: 3.162
  8 in total

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