Literature DB >> 23291661

En-route care capability from point of injury impacts mortality after severe wartime injury.

Jonathan J Morrison1, John Oh, Joseph J DuBose, David J O'Reilly, Robert J Russell, Lorne H Blackbourne, Mark J Midwinter, Todd E Rasmussen.   

Abstract

OBJECTIVE: The objective of this study is to characterize modern point-of-injury (POI) en-route care platforms and to compare mortality among casualties evacuated with conventional military retrieval (CMR) methods to those evacuated with an advanced medical retrieval (AMR) capability.
BACKGROUND: Following a decade of war in Afghanistan, the impact of en-route care capabilities from the POI on mortality is unknown.
METHODS: Casualties evacuated from POI to one level III facility in Afghanistan (July 2008-March 2012) were identified from UK and US trauma registries. Groups comprised those evacuated by a medically qualified provider-led, AMR and those by a medic-led CMR capability. Outcomes were compared per incremental Injury Severity Score (ISS) bins.
RESULTS: Most casualties (n = 1054; 61.2%) were in the low-ISS (1-15) bracket in which there was no difference in en-route care time or mortality between AMR and CMR. Casualties in the mid-ISS bracket (16-50) (n = 583; 33.4%) experienced the same median en-route care time (minutes) on AMR and CMR platforms [78 (58) vs 75 (93); P = 0.542] although those on AMR had shorter time to operation [110 (95) vs 117 (126); P < 0.001]. In this mid-ISS bracket, mortality was lower in the AMR than in the CMR group (12.2% vs 18.2%; P = 0.035). In the high-ISS category (51-75) (n = 75; 4.6%), time to operation was lower in the AMR than the CMR group (66 ± 77 vs 113 ± 122; P = 0.013) but there was no difference in mortality.
CONCLUSIONS: This study characterizes en-route care capabilities from POI in modern combat. Conventional platforms are effective in most casualties with low injury severity. However, a definable injury severity exists for which evacuation with an AMR capability is associated with improved survival.

Entities:  

Mesh:

Year:  2013        PMID: 23291661     DOI: 10.1097/SLA.0b013e31827eefcf

Source DB:  PubMed          Journal:  Ann Surg        ISSN: 0003-4932            Impact factor:   12.969


  21 in total

Review 1.  Advances in damage control resuscitation and surgery: implications on the organization of future military field forces.

Authors:  Homer Tien; Andrew Beckett; Naisan Garraway; Max Talbot; Dylan Pannell; Thamer Alabbasi
Journal:  Can J Surg       Date:  2015-06       Impact factor: 2.089

2.  Pre-trauma center red blood cell transfusion is associated with improved early outcomes in air medical trauma patients.

Authors:  Joshua B Brown; Jason L Sperry; Anisleidy Fombona; Timothy R Billiar; Andrew B Peitzman; Francis X Guyette
Journal:  J Am Coll Surg       Date:  2015-01-24       Impact factor: 6.113

3.  Association of Prehospital Plasma Transfusion With Survival in Trauma Patients With Hemorrhagic Shock When Transport Times Are Longer Than 20 Minutes: A Post Hoc Analysis of the PAMPer and COMBAT Clinical Trials.

Authors:  Anthony E Pusateri; Ernest E Moore; Hunter B Moore; Tuan D Le; Francis X Guyette; Michael P Chapman; Angela Sauaia; Arsen Ghasabyan; James Chandler; Kevin McVaney; Joshua B Brown; Brian J Daley; Richard S Miller; Brian G Harbrecht; Jeffrey A Claridge; Herb A Phelan; William R Witham; A Tyler Putnam; Jason L Sperry
Journal:  JAMA Surg       Date:  2020-02-19       Impact factor: 14.766

Review 4.  [Approaches to pre-hospital bleeding management : Current overview on civilian emergency medicine].

Authors:  H Lier; M Bernhard; J Knapp; C Buschmann; I Bretschneider; B Hossfeld
Journal:  Anaesthesist       Date:  2017-11       Impact factor: 1.041

5.  Pretrauma center red blood cell transfusion is associated with reduced mortality and coagulopathy in severely injured patients with blunt trauma.

Authors:  Joshua B Brown; Mitchell J Cohen; Joseph P Minei; Ronald V Maier; Michaela A West; Timothy R Billiar; Andrew B Peitzman; Ernest E Moore; Joseph Cuschieri; Jason L Sperry
Journal:  Ann Surg       Date:  2015-05       Impact factor: 12.969

6.  Multicenter observational prehospital resuscitation on helicopter study.

Authors:  John B Holcomb; Michael D Swartz; Stacia M DeSantis; Thomas J Greene; Erin E Fox; Deborah M Stein; Eileen M Bulger; Jeffrey D Kerby; Michael Goodman; Martin A Schreiber; Martin D Zielinski; Terence O'Keeffe; Kenji Inaba; Jeffrey S Tomasek; Jeanette M Podbielski; Savitri N Appana; Misung Yi; Charles E Wade
Journal:  J Trauma Acute Care Surg       Date:  2017-07       Impact factor: 3.313

7.  Prehospital synergy: Tranexamic acid and blood transfusion in patients at risk for hemorrhage.

Authors:  Andrew-Paul Deeb; Lara Hoteit; Shimena Li; Francis X Guyette; Brian J Eastridge; Raminder Nirula; Gary A Vercruysse; Terence O'Keeffe; Bellal Joseph; Matthew D Neal; Jason L Sperry; Joshua B Brown
Journal:  J Trauma Acute Care Surg       Date:  2022-04-08       Impact factor: 3.697

8.  Hydroxyethyl starch: putting patient safety first.

Authors:  Julian Bion; Rinaldo Bellomo; John Myburgh; Anders Perner; Konrad Reinhart; Simon Finfer
Journal:  Intensive Care Med       Date:  2013-12-19       Impact factor: 17.440

9.  Evaluation of Prehospital Blood Products to Attenuate Acute Coagulopathy of Trauma in a Model of Severe Injury and Shock in Anesthetized Pigs.

Authors:  Sarah Watts; Giles Nordmann; Karim Brohi; Mark Midwinter; Tom Woolley; Robert Gwyther; Callie Wilson; Henrietta Poon; Emrys Kirkman
Journal:  Shock       Date:  2015-08       Impact factor: 3.454

10.  Association of Prehospital Blood Product Transfusion During Medical Evacuation of Combat Casualties in Afghanistan With Acute and 30-Day Survival.

Authors:  Stacy A Shackelford; Deborah J Del Junco; Nicole Powell-Dunford; Edward L Mazuchowski; Jeffrey T Howard; Russ S Kotwal; Jennifer Gurney; Frank K Butler; Kirby Gross; Zsolt T Stockinger
Journal:  JAMA       Date:  2017-10-24       Impact factor: 56.272

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.