Literature DB >> 23284144

Genome-wide association studies in psychiatry: what have we learned?

Ann L Collins, Patrick F Sullivan.   

Abstract

Genome-wide association studies (GWAS) have been the focus of considerable effort in psychiatry. These efforts have markedly increased knowledge of the genetic basis of psychiatric disorders, and yielded empirical data on genetic architecture critical to addressing long-standing debates in the field. There is a now a clear path to increased knowledge of the 'parts lists' for these disorders.

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Year:  2013        PMID： 23284144      PMCID： PMC4188920          DOI： 10.1192/bjp.bp.112.117002

Source DB:  PubMed          Journal:  Br J Psychiatry        ISSN： 0007-1250            Impact factor:   9.319


  8 in total

Review 1.  Five years of GWAS discovery.

Authors:  Peter M Visscher; Matthew A Brown; Mark I McCarthy; Jian Yang
Journal:  Am J Hum Genet       Date:  2012-01-13       Impact factor: 11.025

Review 2.  Genetic architectures of psychiatric disorders: the emerging picture and its implications.

Authors:  Patrick F Sullivan; Mark J Daly; Michael O'Donovan
Journal:  Nat Rev Genet       Date:  2012-07-10       Impact factor: 53.242

3.  Puzzling over schizophrenia: schizophrenia as a pathway disease.

Authors:  Patrick F Sullivan
Journal:  Nat Med       Date:  2012-02-06       Impact factor: 53.440

Review 4.  A framework for interpreting genome-wide association studies of psychiatric disorders.

Authors: 
Journal:  Mol Psychiatry       Date:  2008-11-11       Impact factor: 15.992

5.  Genome-wide association studies: a primer.

Authors:  A Corvin; N Craddock; P F Sullivan
Journal:  Psychol Med       Date:  2009-11-09       Impact factor: 7.723

6.  A mega-analysis of genome-wide association studies for major depressive disorder.

Authors:  Stephan Ripke; Naomi R Wray; Cathryn M Lewis; Steven P Hamilton; Myrna M Weissman; Gerome Breen; Enda M Byrne; Douglas H R Blackwood; Dorret I Boomsma; Sven Cichon; Andrew C Heath; Florian Holsboer; Susanne Lucae; Pamela A F Madden; Nicholas G Martin; Peter McGuffin; Pierandrea Muglia; Markus M Noethen; Brenda P Penninx; Michele L Pergadia; James B Potash; Marcella Rietschel; Danyu Lin; Bertram Müller-Myhsok; Jianxin Shi; Stacy Steinberg; Hans J Grabe; Paul Lichtenstein; Patrik Magnusson; Roy H Perlis; Martin Preisig; Jordan W Smoller; Kari Stefansson; Rudolf Uher; Zoltan Kutalik; Katherine E Tansey; Alexander Teumer; Alexander Viktorin; Michael R Barnes; Thomas Bettecken; Elisabeth B Binder; René Breuer; Victor M Castro; Susanne E Churchill; William H Coryell; Nick Craddock; Ian W Craig; Darina Czamara; Eco J De Geus; Franziska Degenhardt; Anne E Farmer; Maurizio Fava; Josef Frank; Vivian S Gainer; Patience J Gallagher; Scott D Gordon; Sergey Goryachev; Magdalena Gross; Michel Guipponi; Anjali K Henders; Stefan Herms; Ian B Hickie; Susanne Hoefels; Witte Hoogendijk; Jouke Jan Hottenga; Dan V Iosifescu; Marcus Ising; Ian Jones; Lisa Jones; Tzeng Jung-Ying; James A Knowles; Isaac S Kohane; Martin A Kohli; Ania Korszun; Mikael Landen; William B Lawson; Glyn Lewis; Donald Macintyre; Wolfgang Maier; Manuel Mattheisen; Patrick J McGrath; Andrew McIntosh; Alan McLean; Christel M Middeldorp; Lefkos Middleton; Grant M Montgomery; Shawn N Murphy; Matthias Nauck; Willem A Nolen; Dale R Nyholt; Michael O'Donovan; Högni Oskarsson; Nancy Pedersen; William A Scheftner; Andrea Schulz; Thomas G Schulze; Stanley I Shyn; Engilbert Sigurdsson; Susan L Slager; Johannes H Smit; Hreinn Stefansson; Michael Steffens; Thorgeir Thorgeirsson; Federica Tozzi; Jens Treutlein; Manfred Uhr; Edwin J C G van den Oord; Gerard Van Grootheest; Henry Völzke; Jeffrey B Weilburg; Gonneke Willemsen; Frans G Zitman; Benjamin Neale; Mark Daly; Douglas F Levinson; Patrick F Sullivan
Journal:  Mol Psychiatry       Date:  2012-04-03       Impact factor: 15.992

7.  Hypothesis-driven candidate genes for schizophrenia compared to genome-wide association results.

Authors:  A L Collins; Y Kim; P Sklar; M C O'Donovan; P F Sullivan
Journal:  Psychol Med       Date:  2011-08-19       Impact factor: 7.723

8.  Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo.

Authors:  P F Sullivan; E J C de Geus; G Willemsen; M R James; J H Smit; T Zandbelt; V Arolt; B T Baune; D Blackwood; S Cichon; W L Coventry; K Domschke; A Farmer; M Fava; S D Gordon; Q He; A C Heath; P Heutink; F Holsboer; W J Hoogendijk; J J Hottenga; Y Hu; M Kohli; D Lin; S Lucae; D J Macintyre; W Maier; K A McGhee; P McGuffin; G W Montgomery; W J Muir; W A Nolen; M M Nöthen; R H Perlis; K Pirlo; D Posthuma; M Rietschel; P Rizzu; A Schosser; A B Smit; J W Smoller; J-Y Tzeng; R van Dyck; M Verhage; F G Zitman; N G Martin; N R Wray; D I Boomsma; B W J H Penninx
Journal:  Mol Psychiatry       Date:  2008-12-09       Impact factor: 15.992
  8 in total
  13 in total

Review 1.  The Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup: Posttraumatic Stress Disorder Enters the Age of Large-Scale Genomic Collaboration.

Authors:  Mark W Logue; Ananda B Amstadter; Dewleen G Baker; Laramie Duncan; Karestan C Koenen; Israel Liberzon; Mark W Miller; Rajendra A Morey; Caroline M Nievergelt; Kerry J Ressler; Alicia K Smith; Jordan W Smoller; Murray B Stein; Jennifer A Sumner; Monica Uddin
Journal:  Neuropsychopharmacology       Date:  2015-04-23       Impact factor: 7.853

2.  Thinking About Data, Research Methods, and Statistical Analyses: Commentary on Sijtsma's (2014) "Playing with Data".

Authors:  Irwin D Waldman; Scott O Lilienfeld
Journal:  Psychometrika       Date:  2016-03       Impact factor: 2.500

3.  A polygenic risk score associated with measures of depressive symptoms among older adults.

Authors:  Morgan E Levine; Eileen M Crimmins; Carol A Prescott; Drystan Phillips; Thalida E Arpawong; Jinkook Lee
Journal:  Biodemography Soc Biol       Date:  2014

4.  Psychiatry and developmental psychopathology: Unifying themes and future directions.

Authors:  Theodore P Beauchaine; John N Constantino; Elizabeth P Hayden
Journal:  Compr Psychiatry       Date:  2018-11-01       Impact factor: 3.735

5.  Gene-set Enrichment with Mathematical Biology (GEMB).

Authors:  Amy L Cochran; Kenneth J Nieser; Daniel B Forger; Sebastian Zöllner; Melvin G McInnis
Journal:  Gigascience       Date:  2020-10-09       Impact factor: 6.524

6.  Genome-wide linkage on chromosome 10q26 for a dimensional scale of major depression.

Authors:  Emma E M Knowles; Jack W Kent; D Reese McKay; Emma Sprooten; Samuel R Mathias; Joanne E Curran; Melanie A Carless; Marcio A A de Almeida; H H Goring Harald; Tom D Dyer; Rene L Olvera; Peter T Fox; Ravi Duggirala; Laura Almasy; John Blangero; David C Glahn
Journal:  J Affect Disord       Date:  2015-11-17       Impact factor: 4.839

Review 7.  Genetics of Autism Spectrum Disorder: Current Status and Possible Clinical Applications.

Authors:  Heejeong Yoo
Journal:  Exp Neurobiol       Date:  2015-12-16       Impact factor: 3.261

8.  Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders.

Authors:  Jonathan R I Coleman; Kathryn J Lester; Robert Keers; Marcus R Munafò; Gerome Breen; Thalia C Eley
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2017-06-13       Impact factor: 3.568

9.  Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction.

Authors:  Aritra Bhattacherjee; Mohamed Nadhir Djekidel; Renchao Chen; Wenqiang Chen; Luis M Tuesta; Yi Zhang
Journal:  Nat Commun       Date:  2019-09-13       Impact factor: 14.919

Review 10.  Gut Biofactory-Neurocompetent Metabolites within the Gastrointestinal Tract. A Scoping Review.

Authors:  Karolina Skonieczna-Żydecka; Karolina Jakubczyk; Dominika Maciejewska-Markiewicz; Katarzyna Janda; Karolina Kaźmierczak-Siedlecka; Mariusz Kaczmarczyk; Igor Łoniewski; Wojciech Marlicz
Journal:  Nutrients       Date:  2020-11-01       Impact factor: 5.717
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