Literature DB >> 23273288

Is hospital admission for heart failure really necessary?: the role of the emergency department and observation unit in preventing hospitalization and rehospitalization.

Sean P Collins1, Peter S Pang, Gregg C Fonarow, Clyde W Yancy, Robert O Bonow, Mihai Gheorghiade.   

Abstract

Approximately 800,000 times a year, an emergency physician admits a patient with symptomatic heart failure (HF). Yet only a minority of emergency department patients with HF are severely ill as a result of pulmonary edema, myocardial ischemia, or cardiogenic shock. The majority of patients are not in need of an acute intervention beyond decongestion, and few patients during hospitalization undergo invasive diagnostic testing or therapeutic procedures that require intense monitoring. Although hospitalization is clearly an inflection point, marking a threshold that independently predicts a worse outcome, the exact impact of hospitalization on post-discharge events has not been well elucidated. Thus, large subsets of patients with HF are hospitalized without a clear need for time-sensitive therapies or procedures. The authors estimate that up to 50% of emergency department patients with HF could be safely discharged after a brief period of observation, thus avoiding unnecessary admissions and minimizing readmissions. Observation unit management may be beneficial for low-risk and intermediate-risk patients with HF as continued treatment, and more precise risk stratification may ensue, avoiding inpatient admission. Whether observation unit management is comparable with or superior to the current approach must be determined in a randomized clinical trial. Critical end points include time to symptom resolution and discharge, post-discharge event rates, and a cost-effective analysis of each management strategy. It is the authors' strong assertion that now is the time for such a trial and that the results will be critically important if we are to effectively influence hospitalizations for HF in the near future.
Copyright © 2013 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

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Year:  2013        PMID: 23273288      PMCID: PMC3535319          DOI: 10.1016/j.jacc.2012.08.1022

Source DB:  PubMed          Journal:  J Am Coll Cardiol        ISSN: 0735-1097            Impact factor:   24.094


  31 in total

1.  Emergency department observation of heart failure: preliminary analysis of safety and cost.

Authors:  Alan B Storrow; Sean P Collins; Michael S Lyons; Lynne E Wagoner; W Brian Gibler; Christopher J Lindsell
Journal:  Congest Heart Fail       Date:  2005 Mar-Apr

Review 2.  Pathophysiologic targets in the early phase of acute heart failure syndromes.

Authors:  Mihai Gheorghiade; Leonardo De Luca; Gregg C Fonarow; Gerasimos Filippatos; Marco Metra; Gary S Francis
Journal:  Am J Cardiol       Date:  2005-09-19       Impact factor: 2.778

3.  Improving postdischarge outcomes in patients hospitalized for acute heart failure syndromes.

Authors:  Mihai Gheorghiade; Eric D Peterson
Journal:  JAMA       Date:  2011-06-15       Impact factor: 56.272

4.  In-hospital mortality in patients with acute decompensated heart failure requiring intravenous vasoactive medications: an analysis from the Acute Decompensated Heart Failure National Registry (ADHERE).

Authors:  William T Abraham; Kirkwood F Adams; Gregg C Fonarow; Maria Rosa Costanzo; Robert L Berkowitz; Thierry H LeJemtel; Mei L Cheng; Janet Wynne
Journal:  J Am Coll Cardiol       Date:  2005-07-05       Impact factor: 24.094

5.  Characteristics and outcomes of patients hospitalized for heart failure in the United States: rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE).

Authors:  Kirkwood F Adams; Gregg C Fonarow; Charles L Emerman; Thierry H LeJemtel; Maria Rosa Costanzo; William T Abraham; Robert L Berkowitz; Marie Galvao; Darlene P Horton
Journal:  Am Heart J       Date:  2005-02       Impact factor: 4.749

6.  Outcomes after emergency department discharge with a primary diagnosis of heart failure.

Authors:  J E Rame; M A Sheffield; D L Dries; E B Gardner; K H Toto; C W Yancy; M H Drazner
Journal:  Am Heart J       Date:  2001-10       Impact factor: 4.749

7.  EuroHeart Failure Survey II (EHFS II): a survey on hospitalized acute heart failure patients: description of population.

Authors:  Markku S Nieminen; Dirk Brutsaert; Kenneth Dickstein; Helmut Drexler; Ferenc Follath; Veli-Pekka Harjola; Matthias Hochadel; Michel Komajda; Johan Lassus; Jose Luis Lopez-Sendon; Piotr Ponikowski; Luigi Tavazzi
Journal:  Eur Heart J       Date:  2006-09-25       Impact factor: 29.983

8.  Systolic blood pressure at admission, clinical characteristics, and outcomes in patients hospitalized with acute heart failure.

Authors:  Mihai Gheorghiade; William T Abraham; Nancy M Albert; Barry H Greenberg; Christopher M O'Connor; Lilin She; Wendy Gattis Stough; Clyde W Yancy; James B Young; Gregg C Fonarow
Journal:  JAMA       Date:  2006-11-08       Impact factor: 56.272

9.  Characteristics, treatments, and outcomes of patients with preserved systolic function hospitalized for heart failure: a report from the OPTIMIZE-HF Registry.

Authors:  Gregg C Fonarow; Wendy Gattis Stough; William T Abraham; Nancy M Albert; Mihai Gheorghiade; Barry H Greenberg; Christopher M O'Connor; Jie Lena Sun; Clyde W Yancy; James B Young
Journal:  J Am Coll Cardiol       Date:  2007-08-06       Impact factor: 24.094

10.  Repeated hospitalizations predict mortality in the community population with heart failure.

Authors:  Soko Setoguchi; Lynne Warner Stevenson; Sebastian Schneeweiss
Journal:  Am Heart J       Date:  2007-08       Impact factor: 4.749

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  37 in total

Review 1.  Contemporary strategies in the diagnosis and management of heart failure.

Authors:  Shannon M Dunlay; Naveen L Pereira; Sudhir S Kushwaha
Journal:  Mayo Clin Proc       Date:  2014-03-29       Impact factor: 7.616

2.  The burden of acute heart failure on U.S. emergency departments.

Authors:  Alan B Storrow; Cathy A Jenkins; Wesley H Self; Pauline T Alexander; Tyler W Barrett; Jin H Han; Candace D McNaughton; Benjamin S Heavrin; Mihai Gheorghiade; Sean P Collins
Journal:  JACC Heart Fail       Date:  2014-04-30       Impact factor: 12.035

Review 3.  Initial management of patients with acute heart failure.

Authors:  Gregory J Fermann; Sean P Collins
Journal:  Heart Fail Clin       Date:  2013-06-04       Impact factor: 3.179

4.  ACUTE Heart Failure Risk Stratification.

Authors:  Sean P Collins; Peter S Pang
Journal:  Circulation       Date:  2019-02-26       Impact factor: 29.690

5.  Incidence of Heart Failure Observed in Emergency Departments, Ambulatory Clinics, and Hospitals.

Authors:  Ricky Camplain; Anna Kucharska-Newton; Thomas C Keyserling; J Bradley Layton; Laura Loehr; Gerardo Heiss
Journal:  Am J Cardiol       Date:  2018-03-01       Impact factor: 2.778

Review 6.  Clinical trials in hospitalized heart failure patients: targeting interventions to optimal phenotypic subpopulations.

Authors:  Muthiah Vaduganathan; Javed Butler; Lothar Roessig; Gregg C Fonarow; Stephen J Greene; Marco Metra; Gadi Cotter; Stuart Kupfer; Andrew Zalewski; Naoki Sato; Gerasimos Filippatos; Mihai Gheorghiade
Journal:  Heart Fail Rev       Date:  2015-07       Impact factor: 4.214

7.  Cardiovascular Admissions, Readmissions, and Transitions of Care.

Authors:  Anna Marie Chang; Kristin L Rising
Journal:  Curr Emerg Hosp Med Rep       Date:  2014-03-01

8.  Emergency department visits for heart failure and subsequent hospitalization or observation unit admission.

Authors:  Saul Blecker; Joseph A Ladapo; Kelly M Doran; Keith S Goldfeld; Stuart Katz
Journal:  Am Heart J       Date:  2014-08-08       Impact factor: 4.749

9.  African Americans Are Less Likely to Receive Care by a Cardiologist During an Intensive Care Unit Admission for Heart Failure.

Authors:  Khadijah Breathett; Wenhui G Liu; Larry A Allen; Stacie L Daugherty; Irene V Blair; Jacqueline Jones; Gary K Grunwald; Marc Moss; Tyree H Kiser; Ellen Burnham; R William Vandivier; Brendan J Clark; Eldrin F Lewis; Sula Mazimba; Catherine Battaglia; P Michael Ho; Pamela N Peterson
Journal:  JACC Heart Fail       Date:  2018-05       Impact factor: 12.035

10.  Outpatient Worsening Heart Failure as a Target for Therapy: A Review.

Authors:  Stephen J Greene; Robert J Mentz; G Michael Felker
Journal:  JAMA Cardiol       Date:  2018-03-01       Impact factor: 14.676

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