Literature DB >> 23269737

Mechanisms of linezolid resistance among Staphylococci in a tertiary hospital.

Inmaculada Quiles-Melero1, Rosa Gómez-Gil, María Pilar Romero-Gómez, Ana María Sánchez-Díaz, Manuela de Pablos, Julio García-Rodriguez, Avelino Gutiérrez, Jesús Mingorance.   

Abstract

The mechanisms of linezolid resistance among 86 staphylococcal isolates from two intensive care units were investigated. The most frequent was the G2576T mutation in the 23S rRNA (82%). The cfr gene was found in 17% of the isolates, seven S. aureus and eight S. epidermidis isolates. Four of the S. epidermidis isolates had the G2576T mutation and the cfr gene. In four S. haemolyticus isolates, the mechanism could not be identified.

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Year:  2012        PMID: 23269737      PMCID: PMC3592090          DOI: 10.1128/JCM.01598-12

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN: 0095-1137            Impact factor:   5.948


  26 in total

Review 1.  Resistance to linezolid caused by modifications at its binding site on the ribosome.

Authors:  Katherine S Long; Birte Vester
Journal:  Antimicrob Agents Chemother       Date:  2011-12-05       Impact factor: 5.191

2.  Spread of cfr gene among staphylococci conferring resistance to linezolid in a patient under treatment.

Authors:  Concepción Pérez-Jorge; María-Carolina Isea-Peña; Sarah Heili; Jaime Esteban
Journal:  J Antibiot (Tokyo)       Date:  2011-12-21       Impact factor: 2.649

3.  A new multiplex PCR for easy screening of methicillin-resistant Staphylococcus aureus SCCmec types I-V.

Authors:  K Boye; M D Bartels; I S Andersen; J A Møller; H Westh
Journal:  Clin Microbiol Infect       Date:  2007-04-02       Impact factor: 8.067

4.  Linezolid resistance in Staphylococcus aureus: gene dosage effect, stability, fitness costs, and cross-resistances.

Authors:  Silke Besier; Albrecht Ludwig; Johannes Zander; Volker Brade; Thomas A Wichelhaus
Journal:  Antimicrob Agents Chemother       Date:  2008-01-22       Impact factor: 5.191

5.  DNA methylase modifications and other linezolid resistance mutations in coagulase-negative staphylococci in Italy.

Authors:  Dafne Bongiorno; Floriana Campanile; Gino Mongelli; Maria Teresa Baldi; Rosamaria Provenzani; Silvia Reali; Carolina Lo Russo; Maria Santagati; Stefania Stefani
Journal:  J Antimicrob Chemother       Date:  2010-09-18       Impact factor: 5.790

6.  Linezolid-resistant Staphylococcus aureus isolated from 2006 through 2008 at six hospitals in Japan.

Authors:  Yurika Ikeda-Dantsuji; Hideaki Hanaki; Fuminori Sakai; Kazunori Tomono; Yoshio Takesue; Junichi Honda; Yuriko Nonomiya; Akira Suwabe; Osanori Nagura; Katsunori Yanagihara; Hiroshige Mikamo; Kunihiko Fukuchi; Mitsuo Kaku; Shigeru Kohno; Chie Yanagisawa; Taiji Nakae; Koichiro Yoshida; Yoshihito Niki
Journal:  J Infect Chemother       Date:  2010-07-07       Impact factor: 2.211

Review 7.  Linezolid in vitro: mechanism and antibacterial spectrum.

Authors:  David M Livermore
Journal:  J Antimicrob Chemother       Date:  2003-05       Impact factor: 5.790

8.  Nosocomial outbreak of linezolid-resistant Enterococcus faecalis infection in a tertiary care hospital.

Authors:  Rosa Gómez-Gil; Maria Pilar Romero-Gómez; Africa García-Arias; M Gallego Ubeda; M Sota Busselo; Ramón Cisterna; Avelino Gutiérrez-Altés; Jesus Mingorance
Journal:  Diagn Microbiol Infect Dis       Date:  2009-08-29       Impact factor: 2.803

9.  Clinical and microbiological aspects of linezolid resistance mediated by the cfr gene encoding a 23S rRNA methyltransferase.

Authors:  Cesar A Arias; Martha Vallejo; Jinnethe Reyes; Diana Panesso; Jaime Moreno; Elizabeth Castañeda; Maria V Villegas; Barbara E Murray; John P Quinn
Journal:  J Clin Microbiol       Date:  2008-01-03       Impact factor: 5.948

10.  Mutations in ribosomal protein L3 are associated with oxazolidinone resistance in staphylococci of clinical origin.

Authors:  Jeffrey B Locke; Mark Hilgers; Karen Joy Shaw
Journal:  Antimicrob Agents Chemother       Date:  2009-10-05       Impact factor: 5.191

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  8 in total

1.  Dalbavancin Alone and in Combination with Ceftaroline against Four Different Phenotypes of Staphylococcus aureus in a Simulated Pharmacodynamic/Pharmacokinetic Model.

Authors:  Razieh Kebriaei; Seth A Rice; Kyle C Stamper; Michael J Rybak
Journal:  Antimicrob Agents Chemother       Date:  2019-03-27       Impact factor: 5.191

Review 2.  Coagulase-negative staphylococci.

Authors:  Karsten Becker; Christine Heilmann; Georg Peters
Journal:  Clin Microbiol Rev       Date:  2014-10       Impact factor: 26.132

Review 3.  Clinical Infections, Antibiotic Resistance, and Pathogenesis of Staphylococcus haemolyticus.

Authors:  Hala O Eltwisy; Howida Omar Twisy; Mahmoud Hr Hafez; Ibrahim M Sayed; Mohamed A El-Mokhtar
Journal:  Microorganisms       Date:  2022-05-31

Review 4.  Streptomyces as a Prominent Resource of Future Anti-MRSA Drugs.

Authors:  Hefa Mangzira Kemung; Loh Teng-Hern Tan; Tahir Mehmood Khan; Kok-Gan Chan; Priyia Pusparajah; Bey-Hing Goh; Learn-Han Lee
Journal:  Front Microbiol       Date:  2018-09-24       Impact factor: 5.640

5.  Linezolid resistant coagulase negative staphylococci (LRCoNS) with novel mutations causing blood stream infections (BSI) in India.

Authors:  Gajanand Mittal; Vasundhra Bhandari; Rajni Gaind; Vandana Rani; Shimpi Chopra; Reetika Dawar; Raman Sardana; P K Verma
Journal:  BMC Infect Dis       Date:  2019-08-14       Impact factor: 3.090

Review 6.  The global prevalence of Daptomycin, Tigecycline, Quinupristin/Dalfopristin, and Linezolid-resistant Staphylococcus aureus and coagulase-negative staphylococci strains: a systematic review and meta-analysis.

Authors:  Aref Shariati; Masoud Dadashi; Zahra Chegini; Alex van Belkum; Mehdi Mirzaii; Seyed Sajjad Khoramrooz; Davood Darban-Sarokhalil
Journal:  Antimicrob Resist Infect Control       Date:  2020-04-22       Impact factor: 4.887

7.  Effect of spdC gene expression on virulence and antibiotic resistance in clinical Staphylococcus aureus isolates.

Authors:  Mayada E Bakr; Mona T Kashef; Alaa El-Dien M S Hosny; Mohammed A Ramadan
Journal:  Int Microbiol       Date:  2022-05-24       Impact factor: 3.097

8.  Molecular epidemiology of coagulase-negative bloodstream isolates: detection of Staphylococcus epidermidis ST2, ST7 and linezolid-resistant ST23.

Authors:  Adrián Martínez-Meléndez; Rayo Morfín-Otero; Licet Villarreal-Treviño; Adrián Camacho-Ortíz; Gloria González-González; Jorge Llaca-Díaz; Eduardo Rodríguez-Noriega; Elvira Garza-González
Journal:  Braz J Infect Dis       Date:  2016-07-06       Impact factor: 3.257

  8 in total

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