Literature DB >> 23269506

Cladosporium cladosporioides XJ-AC03, an aconitine-producing endophytic fungus isolated from Aconitum leucostomum.

Kai Yang1, Jie Liang, Qinfan Li, Xiangya Kong, Rui Chen, Yimin Jin.   

Abstract

The endophytic fungus XJ-AC03, which was isolated from the healthy roots of Aconitum leucostomum, produced aconitine when grown in potato dextrose agar (PDA) medium. The presence of aconitine was confirmed by the chromatographic and spectroscopic analyses. The yield of aconitine was recorded as 236.4 μg/g by high performance liquid chromatography (HPLC). The mass spectrometry was shown to be identical to authentic aconitine. Further analysis with nuclear magnetic resonance (NMR) spectroscopy to show the chemical structure of the fungal aconitine indicated that the fungal aconitine produced an NMR spectrum identical to that of authentic aconitine. Strain XJ-AC03 was identified as Cladosporium cladosporioides by its characteristic culture morphology and ITS rDNA sequence analysis.

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Year:  2012        PMID： 23269506     DOI： 10.1007/s11274-012-1246-4

Source DB:  PubMed          Journal:  World J Microbiol Biotechnol        ISSN： 0959-3993            Impact factor:   3.312


  11 in total

1.  Analysis of the aconitine alkaloids in traditional Chinese medicines by nonaqueous capillary electrophoresis using a new recording mode.

Authors:  Shengguo Zhao; Zhongwei Pan; Xingguo Chen; Zhide Hu
Journal:  Biomed Chromatogr       Date:  2004-07       Impact factor: 1.902

2.  Anticancer activity of aconitine-containing herbal extract BC1.

Authors:  Galina I Solyanik; Alexander G Fedorchuk; Olga N Pyaskovskaya; Olga I Dasyukevitch; Natalya N Khranovskaya; Gennadiy N Aksenov; Vladimir V Sobetsky
Journal:  Exp Oncol       Date:  2004-12

3.  Determination of aconitine in body fluids by LC-MS-MS.

Authors:  J Beike; L Frommherz; M Wood; B Brinkmann; H Köhler
Journal:  Int J Legal Med       Date:  2004-10       Impact factor: 2.686

4.  Pharmacokinetics of aconitine in rat skin after oral and transdermal gel administrations.

Authors:  Quan-Long Zhang; Jin-Hong Hu; Zheng-Ping Jia; Dan Wang; Quan-Gang Zhu
Journal:  Biomed Chromatogr       Date:  2011-12-02       Impact factor: 1.902

5.  Studies on the constituents of Aconitum species. IX. The pharmacological properties of pyro-type aconitine alkaloids, components of processed aconite powder 'kako-bushi-matsu': analgesic, antiinflammatory and acute toxic activities.

Authors:  M Murayama; T Mori; H Bando; T Amiya
Journal:  J Ethnopharmacol       Date:  1991-12       Impact factor: 4.360

6.  Comparative research of chemical constituents, antifungal and antitumor properties of ether extracts of Panax ginseng and its endophytic fungus.

Authors:  Li-Li Xu; Ting Han; Jin-Zhong Wu; Qiao-Yan Zhang; Hong Zhang; Bao-Kang Huang; Khalid Rahman; Lu-Ping Qin
Journal:  Phytomedicine       Date:  2009-04-28       Impact factor: 5.340

Review 7.  Aconitum in traditional Chinese medicine: a valuable drug or an unpredictable risk?

Authors:  Judith Singhuber; Ming Zhu; Sonja Prinz; Brigitte Kopp
Journal:  J Ethnopharmacol       Date:  2009-08-03       Impact factor: 4.360

8.  Antiarrhythmic effect of newly synthesized compound 44Bu on model of aconitine-induced arrhythmia -- compared to lidocaine.

Authors:  Ladislava Bartosova; Filip Novak; Marketa Bebarova; Marek Frydrych; Vit Brunclik; Radka Opatrilova; Jana Kolevska; Petr Mokry; Peter Kollar; Vera Strnadova; Pavel Suchy
Journal:  Eur J Pharmacol       Date:  2007-07-31       Impact factor: 4.432

9.  An endophytic taxol-producing fungus from Taxus media, Cladosporium cladosporioides MD2.

Authors:  Peng Zhang; Peng-Peng Zhou; Long-Jiang Yu
Journal:  Curr Microbiol       Date:  2009-05-30       Impact factor: 2.188

10.  An endophytic fungus from Camptotheca acuminata that produces camptothecin and analogues.

Authors:  Souvik Kusari; Sebastian Zühlke; Michael Spiteller
Journal:  J Nat Prod       Date:  2009-01       Impact factor: 4.050
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  5 in total

1.  Cytotoxic and antibacterial naphthoquinones from an endophytic fungus, Cladosporium sp.

Authors:  Md Imdadul Huque Khan; Md Hossain Sohrab; Satyajit Roy Rony; Fakir Shahidullah Tareq; Choudhury Mahmood Hasan; Md Abdul Mazid
Journal:  Toxicol Rep       Date:  2016-10-19

2.  Preparation and Bioactivity of Exopolysaccharide from an Endophytic Fungus Chaetomium sp. of the Medicinal Plant Gynostemma Pentaphylla.

Authors:  Huiru Zhang; Xueqin Wang; Ruifang Li; Xincheng Sun; Siwen Sun; Qiang Li; Chunping Xu
Journal:  Pharmacogn Mag       Date:  2017-07-19       Impact factor: 1.085

3.  Seed germination-influencing bioactive secondary metabolites secreted by the endophyte Cladosporium cladosporioides LWL5.

Authors:  Muhammad Waqas; Abdul Latif Khan; Liaqat Ali; Sang-Mo Kang; Yoon-Ha Kim; In-Jung Lee
Journal:  Molecules       Date:  2013-12-13       Impact factor: 4.411

Review 4.  Fungal Endophytes as Efficient Sources of Plant-Derived Bioactive Compounds and Their Prospective Applications in Natural Product Drug Discovery: Insights, Avenues, and Challenges.

Authors:  Archana Singh; Dheeraj K Singh; Ravindra N Kharwar; James F White; Surendra K Gond
Journal:  Microorganisms       Date:  2021-01-19

5.  Metabolomics and microbiome reveal potential root microbiota affecting the alkaloidal metabolome in Aconitum vilmorinianum Kom.

Authors:  Hongrui Li; Hongdi Shi; Peng Xu; Diqiu Yu
Journal:  BMC Microbiol       Date:  2022-03-09       Impact factor: 3.605
  5 in total

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