OBJECTIVE: The goal of this study is to characterize the theta to beta ratio (THBR) obtained from electroencephalogram (EEG) measures, in a large sample of community and clinical participants with regard to (a) ADHD diagnosis and subtypes, (b) common psychiatric comorbidities, and (c) cognitive correlates. METHOD: The sample includes 871 participants (595 youth and 276 adults) with and without ADHD. All participants underwent extensive assessment, including semistructured diagnostic interviews, cognitive testing, and EEG recording. RESULTS: The THBR did not differ significantly by ADHD status for youth but was significantly lower in adults with ADHD compared with controls. ADHD subtype and psychiatric comorbidities such as disruptive behavior disorders and depression have opposing and significant mediating effects on the THBR. CONCLUSION: The THBR is affected by several mediating factors associated with ADHD such as ADHD subtype and psychiatric comorbidity. More research is needed to understand the functional significance of the THBR in ADHD.
OBJECTIVE: The goal of this study is to characterize the theta to beta ratio (THBR) obtained from electroencephalogram (EEG) measures, in a large sample of community and clinical participants with regard to (a) ADHD diagnosis and subtypes, (b) common psychiatric comorbidities, and (c) cognitive correlates. METHOD: The sample includes 871 participants (595 youth and 276 adults) with and without ADHD. All participants underwent extensive assessment, including semistructured diagnostic interviews, cognitive testing, and EEG recording. RESULTS: The THBR did not differ significantly by ADHD status for youth but was significantly lower in adults with ADHD compared with controls. ADHD subtype and psychiatric comorbidities such as disruptive behavior disorders and depression have opposing and significant mediating effects on the THBR. CONCLUSION: The THBR is affected by several mediating factors associated with ADHD such as ADHD subtype and psychiatric comorbidity. More research is needed to understand the functional significance of the THBR in ADHD.
Authors: Brittany R Alperin; Christiana J Smith; Hanna C Gustafsson; McKenzie T Figuracion; Sarah L Karalunas Journal: J Psychiatr Res Date: 2019-06-18 Impact factor: 4.791
Authors: Katleen Geladé; Tieme W P Janssen; Marleen Bink; Jos W R Twisk; Rosa van Mourik; Athanasios Maras; Jaap Oosterlaan Journal: Eur Child Adolesc Psychiatry Date: 2017-11-02 Impact factor: 4.785
Authors: Matti Gärtner; Maria Strauß; Jue Huang; Eike Ahlers; Holger Bogatsch; Pierre Böhme; Thomas Ethofer; Andreas J Fallgatter; Jürgen Gallinat; Ulrich Hegerl; Isabella Heuser; Knut Hoffmann; Sarah Kittel-Schneider; Andreas Reif; Daniel Schöttle; Stefan Unterecker Journal: Eur Arch Psychiatry Clin Neurosci Date: 2022-07-04 Impact factor: 5.270