Literature DB >> 23261481

Obesity triples the radiation dose of stone protocol computerized tomography.

Agnes J Wang1, Zachariah G Goldsmith, Chu Wang, Giao Nguyen, Gastón M Astroza, Andreas Neisius, Muhammad W Iqbal, Amy M Neville, Carolyn Lowry, Greta Toncheva, Terry T Yoshizumi, Glenn M Preminger, Michael N Ferrandino, Michael E Lipkin.   

Abstract

PURPOSE: Patients with recurrent nephrolithiasis are often evaluated and followed with computerized tomography. Obesity is a risk factor for nephrolithiasis. We evaluated the radiation dose of computerized tomography in obese and nonobese adults.
MATERIALS AND METHODS: We scanned a validated, anthropomorphic male phantom according to our institutional renal stone evaluation protocol. The obese model consisted of the phantom wrapped in 2 Custom Fat Layers (CIRS, Norfolk, Virginia), which have been verified to have the same radiographic tissue density as fat. High sensitivity metal oxide semiconductor field effect transistor dosimeters were placed at 20 organ locations in the phantoms to measure organ specific radiation doses. The nonobese and obese models have an approximate body mass index of 24 and 30 kg/m(2), respectively. Three runs of renal stone protocol computerized tomography were performed on each phantom under automatic tube current modulation. Organ specific absorbed doses were measured and effective doses were calculated.
RESULTS: The bone marrow of each model received the highest dose and the skin received the second highest dose. The mean ± SD effective dose for the nonobese and obese models was 3.04 ± 0.34 and 10.22 ± 0.50 mSv, respectively (p <0.0001).
CONCLUSIONS: The effective dose of stone protocol computerized tomography in obese patients is more than threefold higher than the dose in nonobese patients using automatic tube current modulation. The implication of this finding extends beyond the urological stone population and adds to our understanding of radiation exposure from medical imaging.
Copyright © 2013 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 23261481     DOI: 10.1016/j.juro.2012.12.029

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  8 in total

Review 1.  [Urolithiasis 2016 : Reliable, effective and low radiation exposure].

Authors:  A Neisius; C Thomas; F C Roos; W Jäger; I Tsaur; G Bartsch; T Knoll; A Haferkamp
Journal:  Urologe A       Date:  2016-10       Impact factor: 0.639

2.  Severe obesity is associated with 3-fold higher radiation dose rate during ureteroscopy.

Authors:  Ryan S Hsi; David A Zamora; Kalpana M Kanal; Jonathan D Harper
Journal:  Urology       Date:  2013-08-16       Impact factor: 2.649

3.  Radiation dose index of renal colic protocol CT studies in the United States: a report from the American College of Radiology National Radiology Data Registry.

Authors:  Adam Lukasiewicz; Mythreyi Bhargavan-Chatfield; Laura Coombs; Monica Ghita; Jeffrey Weinreb; Gowthaman Gunabushanam; Christopher L Moore
Journal:  Radiology       Date:  2014-01-27       Impact factor: 11.105

4.  Accuracy of reduced-dose computed tomography for ureteral stones in emergency department patients.

Authors:  Christopher L Moore; Brock Daniels; Monica Ghita; Gowthaman Gunabushanam; Seth Luty; Annette M Molinaro; Dinesh Singh; Cary P Gross
Journal:  Ann Emerg Med       Date:  2014-11-04       Impact factor: 5.721

5.  Assessment of image quality and low-contrast detectability in abdominal CT of obese patients: comparison of a novel integrated circuit with a conventional discrete circuit detector at different tube voltages.

Authors:  A Euler; T Heye; M Kekelidze; G Bongartz; Z Szucs-Farkas; C Sommer; B Schmidt; Sebastian T Schindera
Journal:  Eur Radiol       Date:  2014-10-15       Impact factor: 5.315

6.  Chest CT screening in patients with overweight or obesity using spectral shaping at 150 kVp: compared with 120 kVp protocol and spectral shaping at 100 kVp protocol.

Authors:  Jianwen Li; Zhifeng Mai; Zhihong Zhang; Jiamang Cui; Mingjie Yang; Xia Ma; Yan Wang
Journal:  Jpn J Radiol       Date:  2020-02-11       Impact factor: 2.374

7.  Evaluation of ultralow-dose computed tomography on detection of pulmonary nodules in overweight or obese adult patients.

Authors:  Xiaowan Guo; Dezhao Jia; Lei He; Xudong Jia; Danqing Zhang; Yana Dou; Shanshan Shen; Hong Ji; Shuqian Zhang; Yingmin Chen
Journal:  J Appl Clin Med Phys       Date:  2022-03-16       Impact factor: 2.102

8.  Development of a Model of the Acute and Delayed Effects of High Dose Radiation Exposure in Jackson Diversity Outbred Mice; Comparison to Inbred C57BL/6 Mice.

Authors:  Andrea M Patterson; P Artur Plett; Hui Lin Chua; Carol H Sampson; Alexa Fisher; Hailin Feng; Joseph L Unthank; Steven J Miller; Barry P Katz; Thomas J MacVittie; Christie M Orschell
Journal:  Health Phys       Date:  2020-11       Impact factor: 2.922

  8 in total

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