BACKGROUND: Although hospitalization is recognized as an important cause of reduction in physical activity in daily life (PADL) in COPD, there is only one study evaluating this effect, and it was performed in European COPD patients who have a lower PADL than that of South American COPD patients. OBJECTIVES: To investigate the effect of hospitalization due to acute exacerbation of PADL in Brazilian COPD patients and to evaluate the factors that determines the physical activity levels during hospitalization and after discharge. METHODS: PADL was quantified using a 3-axis accelerometer on the 3rd day of hospitalization and 1 month after discharge in Brazilian COPD patients who were hospitalized due to disease exacerbation. Six-minute walking distance (6MWD), lower limb strength and pulmonary function were also evaluated. RESULTS: A total of 20 patients completed the study. During hospitalization, patients spent most of the time (87%) lying down or sitting; however, 1 month after they were walking >40 min/day. In addition, patients with prior hospitalization had a lower level of physical activity compared to those without a previous history of hospitalization. The time spent walking during hospitalization was significantly explained by the quadriceps strength (r(2) = 0.29; p < 0.05), while 1 month after, the time spent walking was only significantly explained by the 6MWD (r(2) = 0.51; p = 0.02). CONCLUSIONS: Brazilian COPD patients are inactive during hospitalization but become active 1 month after discharge. Previously hospitalized are more inactive both during and after exacerbation. The quadriceps strength and 6MWD explain the physical activity levels during hospitalization and at home, respectively.
BACKGROUND: Although hospitalization is recognized as an important cause of reduction in physical activity in daily life (PADL) in COPD, there is only one study evaluating this effect, and it was performed in European COPDpatients who have a lower PADL than that of South American COPDpatients. OBJECTIVES: To investigate the effect of hospitalization due to acute exacerbation of PADL in Brazilian COPDpatients and to evaluate the factors that determines the physical activity levels during hospitalization and after discharge. METHODS: PADL was quantified using a 3-axis accelerometer on the 3rd day of hospitalization and 1 month after discharge in Brazilian COPDpatients who were hospitalized due to disease exacerbation. Six-minute walking distance (6MWD), lower limb strength and pulmonary function were also evaluated. RESULTS: A total of 20 patients completed the study. During hospitalization, patients spent most of the time (87%) lying down or sitting; however, 1 month after they were walking >40 min/day. In addition, patients with prior hospitalization had a lower level of physical activity compared to those without a previous history of hospitalization. The time spent walking during hospitalization was significantly explained by the quadriceps strength (r(2) = 0.29; p < 0.05), while 1 month after, the time spent walking was only significantly explained by the 6MWD (r(2) = 0.51; p = 0.02). CONCLUSIONS: Brazilian COPDpatients are inactive during hospitalization but become active 1 month after discharge. Previously hospitalized are more inactive both during and after exacerbation. The quadriceps strength and 6MWD explain the physical activity levels during hospitalization and at home, respectively.
Authors: Rodrigo Cerqueira Borges; Celso R F Carvalho; Alexandra Siqueira Colombo; Mariucha Pereira da Silva Borges; Francisco Garcia Soriano Journal: Intensive Care Med Date: 2015-06-25 Impact factor: 17.440
Authors: Ayedh D Alahmari; Anant R C Patel; Beverly S Kowlessar; Alex J Mackay; Richa Singh; Jadwiga A Wedzicha; Gavin C Donaldson Journal: BMC Pulm Med Date: 2014-06-02 Impact factor: 3.317
Authors: Anne-Kathrin Rausch-Osthoff; Malcolm Kohler; Noriane A Sievi; Christian F Clarenbach; Arnoldus Jr van Gestel Journal: Multidiscip Respir Med Date: 2014-07-03