Literature DB >> 2324009

Novel antibiotics, furaquinocins A and B. Taxonomy, fermentation, isolation and physico-chemical and biological characteristics.

K Komiyama1, S Funayama, Y Anraku, M Ishibashi, Y Takahashi, S Omura.   

Abstract

Two novel antibiotics, furaquinocins A and B were isolated from the culture broth of Streptomyces sp. KO-3988. These antibiotics possess cytocidal activities against HeLa S3 cells in vitro at concentrations of 3.1 micrograms/ml for A and 1.6 micrograms/ml for B. Neither substance possessed antimicrobial activities against Gram-positive and Gram-negative bacteria, fungi or yeast at a concentration of 1,000 micrograms/ml.

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Year:  1990        PMID: 2324009     DOI: 10.7164/antibiotics.43.247

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  9 in total

1.  Detection of eubacterial 3-hydroxy-3-methylglutaryl coenzyme a reductases from natural populations of actinomycetes.

Authors:  J M Sigmund; D C Clark; F A Rainey; A S Anderson
Journal:  Microb Ecol       Date:  2003-05-21       Impact factor: 4.552

Review 2.  Thom Award Lecture. Trends in the search for bioactive microbial metabolites.

Authors:  S Omura
Journal:  J Ind Microbiol       Date:  1992-09

3.  Meroterpenoid natural products from Streptomyces bacteria - the evolution of chemoenzymatic syntheses.

Authors:  Lauren A M Murray; Shaun M K McKinnie; Bradley S Moore; Jonathan H George
Journal:  Nat Prod Rep       Date:  2020-06-30       Impact factor: 13.423

4.  Identification and dereplication of endophytic Colletotrichum strains by MALDI TOF mass spectrometry and molecular networking.

Authors:  Morgane Barthélemy; Vincent Guérineau; Grégory Genta-Jouve; Mélanie Roy; Jérôme Chave; Régis Guillot; Léonie Pellissier; Jean-Luc Wolfender; Didier Stien; Véronique Eparvier; David Touboul
Journal:  Sci Rep       Date:  2020-11-13       Impact factor: 4.379

5.  Biosynthesis of a natural polyketide-isoprenoid hybrid compound, furaquinocin A: identification and heterologous expression of the gene cluster.

Authors:  Takashi Kawasaki; Yutaka Hayashi; Tomohisa Kuzuyama; Kazuo Furihata; Nobuya Itoh; Haruo Seto; Tohru Dairi
Journal:  J Bacteriol       Date:  2006-02       Impact factor: 3.490

6.  Regiospecificities and prenylation mode specificities of the fungal indole diterpene prenyltransferases AtmD and PaxD.

Authors:  Chengwei Liu; Atsushi Minami; Motoyoshi Noike; Hiroaki Toshima; Hideaki Oikawa; Tohru Dairi
Journal:  Appl Environ Microbiol       Date:  2013-09-13       Impact factor: 4.792

7.  Functional characterization of the promiscuous prenyltransferase responsible for furaquinocin biosynthesis: identification of a physiological polyketide substrate and its prenylated reaction products.

Authors:  Takuto Kumano; Takeo Tomita; Makoto Nishiyama; Tomohisa Kuzuyama
Journal:  J Biol Chem       Date:  2010-10-11       Impact factor: 5.157

Review 8.  Bacterial terpenome.

Authors:  Jeffrey D Rudolf; Tyler A Alsup; Baofu Xu; Zining Li
Journal:  Nat Prod Rep       Date:  2021-05-26       Impact factor: 15.111

Review 9.  Dihydronaphthofurans: synthetic strategies and applications.

Authors:  Abolfazl Olyaei; Mahdieh Sadeghpour
Journal:  RSC Adv       Date:  2020-02-05       Impact factor: 4.036

  9 in total

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