Literature DB >> 23211766

Tyrosyl DNA phosphodiesterase 2, an enzyme fit for purpose.

Keith W Caldecott.   

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Year:  2012        PMID： 23211766     DOI： 10.1038/nsmb.2455

Source DB:  PubMed          Journal:  Nat Struct Mol Biol        ISSN： 1545-9985            Impact factor:   15.369


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  22 in total

1.  26 S proteasome-mediated degradation of topoisomerase II cleavable complexes.

Authors:  Y Mao; S D Desai; C Y Ting; J Hwang; L F Liu
Journal:  J Biol Chem       Date:  2001-08-23       Impact factor: 5.157

2.  The Bloom's syndrome helicase suppresses crossing over during homologous recombination.

Authors:  Leonard Wu; Ian D Hickson
Journal:  Nature       Date:  2003-12-18       Impact factor: 49.962

3.  Human TOP3: a single-copy gene encoding DNA topoisomerase III.

Authors:  R Hanai; P R Caron; J C Wang
Journal:  Proc Natl Acad Sci U S A       Date:  1996-04-16       Impact factor: 11.205

4.  Model for MLL translocations in therapy-related leukemia involving topoisomerase IIβ-mediated DNA strand breaks and gene proximity.

Authors:  Ian G Cowell; Zbyslaw Sondka; Kayleigh Smith; Ka Cheong Lee; Catriona M Manville; Malgorzata Sidorczuk-Lesthuruge; Holly Ashlene Rance; Kay Padget; Graham Hunter Jackson; Noritaka Adachi; Caroline A Austin
Journal:  Proc Natl Acad Sci U S A       Date:  2012-05-21       Impact factor: 11.205

5.  TTRAP, a novel protein that associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor-associated factors (TRAFs), and that inhibits nuclear factor-kappa B activation.

Authors:  S Pype; W Declercq; A Ibrahimi; C Michiels; J G Van Rietschoten; N Dewulf; M de Boer; P Vandenabeele; D Huylebroeck; J E Remacle
Journal:  J Biol Chem       Date:  2000-06-16       Impact factor: 5.157

6.  An RNA virus hijacks an incognito function of a DNA repair enzyme.

Authors:  Richard Virgen-Slane; Janet M Rozovics; Kerry D Fitzgerald; Tuan Ngo; Wayne Chou; Gerbrand J van der Heden van Noort; Dmitri V Filippov; Paul D Gershon; Bert L Semler
Journal:  Proc Natl Acad Sci U S A       Date:  2012-08-20       Impact factor: 11.205

7.  Crystal structure of the human ubiquitin-activating enzyme 5 (UBA5) bound to ATP: mechanistic insights into a minimalistic E1 enzyme.

Authors:  John-Paul Bacik; John R Walker; Mohsin Ali; Aaron D Schimmer; Sirano Dhe-Paganon
Journal:  J Biol Chem       Date:  2010-04-05       Impact factor: 5.157

8.  EAPII interacts with ETS1 and modulates its transcriptional function.

Authors:  Huiping Pei; John S Yordy; Qixin Leng; Qinghua Zhao; Dennis K Watson; Runzhao Li
Journal:  Oncogene       Date:  2003-05-08       Impact factor: 9.867

9.  TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1.

Authors:  Zhihong Zeng; Abhishek Sharma; Limei Ju; Junko Murai; Lieve Umans; Liesbeth Vermeire; Yves Pommier; Shunichi Takeda; Danny Huylebroeck; Keith W Caldecott; Sherif F El-Khamisy
Journal:  Nucleic Acids Res       Date:  2012-06-26       Impact factor: 16.971

10.  Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.

Authors:  Ke Shi; Kayo Kurahashi; Rui Gao; Susan E Tsutakawa; John A Tainer; Yves Pommier; Hideki Aihara
Journal:  Nat Struct Mol Biol       Date:  2012-10-28       Impact factor: 15.369
View more
  10 in total

Review 1.  Nonhomologous end joining: a good solution for bad ends.

Authors:  Crystal A Waters; Natasha T Strande; David W Wyatt; John M Pryor; Dale A Ramsden
Journal:  DNA Repair (Amst)       Date:  2014-03-14

2.  Synthesis and structure-activity relationship of furoquinolinediones as inhibitors of Tyrosyl-DNA phosphodiesterase 2 (TDP2).

Authors:  Le-Mao Yu; Zhu Hu; Yu Chen; Azhar Ravji; Sophia Lopez; Caroline B Plescia; Qian Yu; Hui Yang; Monica Abdelmalak; Sourav Saha; Keli Agama; Evgeny Kiselev; Christophe Marchand; Yves Pommier; Lin-Kun An
Journal:  Eur J Med Chem       Date:  2018-04-12       Impact factor: 6.514

3.  Discovery of selective inhibitors of tyrosyl-DNA phosphodiesterase 2 by targeting the enzyme DNA-binding cleft.

Authors:  Bradley R Kossmann; Monica Abdelmalak; Sophia Lopez; Gabrielle Tender; Chunli Yan; Yves Pommier; Christophe Marchand; Ivaylo Ivanov
Journal:  Bioorg Med Chem Lett       Date:  2016-05-24       Impact factor: 2.823

4.  Involvement of the host DNA-repair enzyme TDP2 in formation of the covalently closed circular DNA persistence reservoir of hepatitis B viruses.

Authors:  Christian Königer; Ida Wingert; Moritz Marsmann; Christine Rösler; Jürgen Beck; Michael Nassal
Journal:  Proc Natl Acad Sci U S A       Date:  2014-09-08       Impact factor: 11.205

5.  Differential and common DNA repair pathways for topoisomerase I- and II-targeted drugs in a genetic DT40 repair cell screen panel.

Authors:  Yuko Maede; Hiroyasu Shimizu; Toru Fukushima; Toshiaki Kogame; Terukazu Nakamura; Tsuneharu Miki; Shunichi Takeda; Yves Pommier; Junko Murai
Journal:  Mol Cancer Ther       Date:  2013-10-15       Impact factor: 6.261

6.  TDP2 suppresses chromosomal translocations induced by DNA topoisomerase II during gene transcription.

Authors:  Fernando Gómez-Herreros; Guido Zagnoli-Vieira; Ioanna Ntai; María Isabel Martínez-Macías; Rhona M Anderson; Andrés Herrero-Ruíz; Keith W Caldecott
Journal:  Nat Commun       Date:  2017-08-10       Impact factor: 14.919

Review 7.  Tyrosyl-DNA Phosphodiesterase I N-Terminal Domain Modifications and Interactions Regulate Cellular Function.

Authors:  Evan J Brettrager; Isaac A Segura; Robert C A M van Waardenburg
Journal:  Genes (Basel)       Date:  2019-11-06       Impact factor: 4.096

Review 8.  DNA Double Strand Breaks and Chromosomal Translocations Induced by DNA Topoisomerase II.

Authors:  Fernando Gómez-Herreros
Journal:  Front Mol Biosci       Date:  2019-12-10

9.  GCNA Interacts with Spartan and Topoisomerase II to Regulate Genome Stability.

Authors:  Gregoriy A Dokshin; Gregory M Davis; Ashley D Sawle; Matthew D Eldridge; Peter K Nicholls; Taylin E Gourley; Katherine A Romer; Luke W Molesworth; Hannah R Tatnell; Ahmet R Ozturk; Dirk G de Rooij; Gregory J Hannon; David C Page; Craig C Mello; Michelle A Carmell
Journal:  Dev Cell       Date:  2019-12-12       Impact factor: 12.270

10.  Isoeugenol is a selective potentiator of camptothecin cytotoxicity in vertebrate cells lacking TDP1.

Authors:  Waheba Elsayed; Lamia El-Shafie; Mohamed K Hassan; Mohamed A Farag; Sherif F El-Khamisy
Journal:  Sci Rep       Date:  2016-05-25       Impact factor: 4.379
  10 in total

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