Literature DB >> 23208618

Core-shell hydrogel microcapsules for improved islets encapsulation.

Minglin Ma1, Alan Chiu, Gaurav Sahay, Joshua C Doloff, Nimit Dholakia, Raj Thakrar, Joshua Cohen, Arturo Vegas, Delai Chen, Kaitlin M Bratlie, Tram Dang, Roger L York, Jennifer Hollister-Lock, Gordon C Weir, Daniel G Anderson.   

Abstract

Islets microencapsulation holds great promise to treat type 1 diabetes. Currently used alginate microcapsules often have islets protruding outside capsules, leading to inadequate immuno-protection. A novel design of microcapsules with core-shell structures using a two-fluid co-axial electro-jetting is reported. Improved encapsulation and diabetes correction is achieved in a single step by simply confining the islets in the core region of the capsules.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2012        PMID： 23208618      PMCID： PMC3814167          DOI： 10.1002/adhm.201200341

Source DB:  PubMed          Journal:  Adv Healthc Mater        ISSN： 2192-2640            Impact factor:   9.933


  44 in total

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Journal:  Nat Med       Date:  2003-01       Impact factor: 53.440

Review 2.  Microfluidic encapsulation of cells in polymer microgels.

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Journal:  Small       Date:  2012-03-29       Impact factor: 13.281

3.  Microencapsulated pancreatic islet allografts into nonimmunosuppressed patients with type 1 diabetes: first two cases.

Authors:  Riccardo Calafiore; Giuseppe Basta; Giovanni Luca; Angelo Lemmi; M Pia Montanucci; Giuseppe Calabrese; Leda Racanicchi; Francesca Mancuso; Paolo Brunetti
Journal:  Diabetes Care       Date:  2006-01       Impact factor: 19.112

Review 4.  Alginate-based microcapsules for immunoisolation of pancreatic islets.

Authors:  Paul de Vos; Marijke M Faas; Berit Strand; Ricardo Calafiore
Journal:  Biomaterials       Date:  2006-08-01       Impact factor: 12.479

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7.  Live encapsulated porcine islets from a type 1 diabetic patient 9.5 yr after xenotransplantation.

Authors:  Robert B Elliott; Livia Escobar; Paul L J Tan; Maria Muzina; Sahar Zwain; Christina Buchanan
Journal:  Xenotransplantation       Date:  2007-03       Impact factor: 3.907

8.  Normalization of diabetes in spontaneously diabetic cynomologus monkeys by xenografts of microencapsulated porcine islets without immunosuppression.

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9.  Continuous concentric lamellar block copolymer nanofibers with long range order.

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  35 in total

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2.  Designing hydrogels for controlled drug delivery.

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Review 3.  Bioprinting an Artificial Pancreas for Type 1 Diabetes.

Authors:  Juewan Kim; Kyungwon Kang; Christopher J Drogemuller; Gordon G Wallace; P Toby Coates
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Review 4.  Generation and manipulation of hydrogel microcapsules by droplet-based microfluidics for mammalian cell culture.

Authors:  Haishui Huang; Yin Yu; Yong Hu; Xiaoming He; O Berk Usta; Martin L Yarmush
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Review 5.  Nanotechnology in cell replacement therapies for type 1 diabetes.

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6.  One-step microfluidic generation of pre-hatching embryo-like core-shell microcapsules for miniaturized 3D culture of pluripotent stem cells.

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7.  Microscale Biomaterials with Bioinspired Complexity of Early Embryo Development and in the Ovary for Tissue Engineering and Regenerative Medicine.

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Journal:  ACS Biomater Sci Eng       Date:  2016-12-01

8.  Electrohydrodynamic atomization: A two-decade effort to produce and process micro-/nanoparticulate materials.

Authors:  Jingwei Xie; Jiang Jiang; Pooya Davoodi; M P Srinivasan; Chi-Hwa Wang
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9.  Hydrogel Encapsulation Facilitates Rapid-Cooling Cryopreservation of Stem Cell-Laden Core-Shell Microcapsules as Cell-Biomaterial Constructs.

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Journal:  Adv Healthc Mater       Date:  2017-11-27       Impact factor: 9.933

Review 10.  Granular hydrogels: emergent properties of jammed hydrogel microparticles and their applications in tissue repair and regeneration.

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