Literature DB >> 23192002

Enhanced cellular uptake and gene delivery of glioblastoma with deferoxamine-coated nanoparticle/plasmid DNA/branched polyethylenimine composites.

Ken Cham-Fai Leung1, Chun-Pong Chak, Siu-Fung Lee, Josie M Y Lai, Xiao-Ming Zhu, Yi-Xiang J Wang, Kathy W Y Sham, Christopher H K Cheng.   

Abstract

Ternary composite nanomaterials based on deferoxamine-coated superparamagnetic iron oxide nanoparticles (8-10 nm), circular plasmid DNA (~4 kb) with fluorescent/luminescent reporter group, and branched polyethylenimine (25 kDa, PDI = 2.5) were prepared and compared in terms of their efficiencies in transfecting brain tumor cells at low concentration.

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Year:  2012        PMID： 23192002     DOI： 10.1039/c2cc36663k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

1.  Ternary hybrid nanocomposites for gene delivery and magnetic resonance imaging of hepatocellular carcinoma cells.

Authors:  Ken Cham-Fai Leung; Chi-Hin Wong; Xiao-Ming Zhu; Siu-Fung Lee; Kathy W Y Sham; Josie M Y Lai; Chun-Pong Chak; Yi-Xiang J Wang; Christopher H K Cheng
Journal:  Quant Imaging Med Surg       Date:  2013-12

2.  Evaluation of biocompatible alginate- and deferoxamine-coated ternary composites for magnetic resonance imaging and gene delivery into glioblastoma cells.

Authors:  Ken Cham-Fai Leung; Kathy W Y Sham; Chun-Pong Chak; Josie M Y Lai; Siu-Fung Lee; Yì-Xiáng J Wáng; Christopher H K Cheng
Journal:  Quant Imaging Med Surg       Date:  2015-06

3.  Coating barium titanate nanoparticles with polyethylenimine improves cellular uptake and allows for coupled imaging and gene delivery.

Authors:  Christopher Dempsey; Isac Lee; Katie R Cowan; Junghae Suh
Journal:  Colloids Surf B Biointerfaces       Date:  2013-08-01       Impact factor: 5.268

4.  High-Throughput Screening Platform for Nanoparticle-Mediated Alterations of DNA Repair Capacity.

Authors:  Sneh M Toprani; Dimitrios Bitounis; Qiansheng Huang; Nathalia Oliveira; Kee Woei Ng; Chor Yong Tay; Zachary D Nagel; Philip Demokritou
Journal:  ACS Nano       Date:  2021-03-12       Impact factor: 15.881

Review 5.  Molecular Imaging with MRI: Potential Application in Pancreatic Cancer.

Authors:  Chen Chen; Chang Qiang Wu; Tian Wu Chen; Meng Yue Tang; Xiao Ming Zhang
Journal:  Biomed Res Int       Date:  2015-10-22       Impact factor: 3.411
  5 in total

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