Literature DB >> 23175246

Rhodium-catalyzed cysteine modification with diazo reagents.

Rituparna Kundu1, Zachary T Ball.   

Abstract

A simple rhodium(II) complex catalyzes cysteine modification with diazo reagents. The reaction is marked by clean cysteine selectivity and mild reaction conditions. The resulting linkage is significantly more stable in human plasma serum, when compared to common maleimide reagents.

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Year:  2012        PMID: 23175246     DOI: 10.1039/c2cc37323h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  3 in total

1.  Optimized diazo scaffold for protein esterification.

Authors:  Kalie A Mix; Ronald T Raines
Journal:  Org Lett       Date:  2015-05-04       Impact factor: 6.005

Review 2.  Organometallic catalysis in aqueous and biological environments: harnessing the power of metal carbenes.

Authors:  Sara Gutiérrez; María Tomás-Gamasa; José Luis Mascareñas
Journal:  Chem Sci       Date:  2022-05-16       Impact factor: 9.969

3.  Convenient analysis of protein modification by chemical blotting with fluorogenic "click" reagents.

Authors:  Jun Ohata; Farrukh Vohidov; Zachary T Ball
Journal:  Mol Biosyst       Date:  2015-11
  3 in total

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